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Related papers: Multilevel models for continuous outcomes

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Cluster-level dynamic treatment regimens can be used to guide sequential, intervention or treatment decision-making at the cluster level in order to improve outcomes at the individual or patient-level. In a cluster-level DTR, the…

Methodology · Statistics 2016-07-15 Timothy NeCamp , Amy Kilbourne , Daniel Almirall

Usually in Latent Class Analysis (LCA), external predictors are taken to be cluster conditional probability predictors (LC models with covariates), and/or score conditional probability predictors (LC regression models). In such cases, their…

Methodology · Statistics 2018-01-08 Roberto Di Mari , Antonio Punzo , Zsuzsa Bakk

Traditionally, spline or kernel approaches in combination with parametric estimation are used to infer the linear coefficient (fixed effects) in a partially linear mixed-effects model for repeated measurements. Using machine learning…

Methodology · Statistics 2023-04-03 Corinne Emmenegger , Peter Bühlmann

In classical study designs, the aim is often to learn about the effects of a treatment or intervention on a single outcome; in many modern studies, however, data on multiple outcomes are collected and it is of interest to explore effects on…

Methodology · Statistics 2017-06-15 Edward H. Kennedy , Shreya Kangovi , Nandita Mitra

This article concerns a class of generalized linear mixed models for clustered data, where the random effects are mapped uniquely onto the grouping structure and are independent between groups. We derive necessary and sufficient conditions…

Methodology · Statistics 2017-09-20 Jarod Y. L. Lee , Peter J. Green , Louise M. Ryan

Education systems around the world increasingly rely on school value-added models to hold schools to account. These models typically focus on a limited number of academic outcomes, failing to recognise the broader range of non-academic…

Applications · Statistics 2020-01-08 Lucy Prior , Harvey Goldstein , George Leckie

We present a domain-general account of causation that applies to settings in which macro-level causal relations between two systems are of interest, but the relevant causal features are poorly understood and have to be aggregated from vast…

Machine Learning · Statistics 2015-12-29 Krzysztof Chalupka , Pietro Perona , Frederick Eberhardt

Longitudinal studies of a binary outcome are common in the health, social, and behavioral sciences. In general, a feature of random effects logistic regression models for longitudinal binary data is that the marginal functional form, when…

Forecasting with longitudinal data has been rarely studied. Most of the available studies are for continuous response and all of them are for univariate response. In this study, we consider forecasting multivariate longitudinal binary data.…

Applications · Statistics 2014-03-13 Ozgur Asar , Ozlem Ilk

Multivariate regression model is a natural generalization of the classical univari- ate regression model for fitting multiple responses. In this paper, we propose a high- dimensional multivariate conditional regression model for…

Machine Learning · Statistics 2016-11-26 Junhui Wang

Heterogeneity is a hallmark of complex diseases. Regression-based heterogeneity analysis, which is directly concerned with outcome-feature relationships, has led to a deeper understanding of disease biology. Such an analysis identifies the…

Methodology · Statistics 2022-11-29 Ziye Luo , Xinyue Yao , Yifan Sun , Xinyan Fan

Recent studies increasingly adopt simulation-based machine learning (ML) models to analyze critical infrastructure system resilience. For realistic applications, these ML models consider the component-level characteristics that influence…

Machine Learning · Computer Science 2022-05-09 Srijith Balakrishnan , Beatrice Cassottana , Arun Verma

Cluster-weighted factor analyzers (CWFA) are a versatile class of mixture models designed to estimate the joint distribution of a random vector that includes a response variable along with a set of explanatory variables. They are…

Methodology · Statistics 2024-11-07 Xiaoke Qin , Francesca Martella , Sanjeena Subedi

This tutorial demonstrates the estimation and interpretation of the Multilevel Social Relations Model for dyadic data. The Social Relations Model is appropriate for data structures in which individuals appear multiple times as both the…

Applications · Statistics 2019-08-01 Jeremy Koster , George Leckie , Brandy Aven , Christopher Charlton

An extension of the latent class model is presented for clustering categorical data by relaxing the classical "class conditional independence assumption" of variables. This model consists in grouping the variables into inter-independent and…

Computation · Statistics 2015-10-01 Matthieu Marbac , Christophe Biernacki , Vincent Vandewalle

This paper focuses on the substantive application of multilevel LCA to the evolution of citizenship norms in a diverse array of democratic countries. To do so, we present a two-stage approach to fit multilevel latent class models: in the…

Methodology · Statistics 2023-07-21 Roberto Di Mari , Zsuzsa Bakk , Jennifer Oser , Jouni Kuha

Clustering is commonly performed as an initial analysis step for uncovering structure in 'omics datasets, e.g. to discover molecular subtypes of disease. The high-throughput, high-dimensional nature of these datasets means that they provide…

Methodology · Statistics 2023-03-02 Paul D. W. Kirk , Filippo Pagani , Sylvia Richardson

Dynamic prediction of time-to-event outcomes using longitudinal data is highly useful in clinical research and practice. A common strategy is the joint modeling of longitudinal and time-to-event data. The shared random effect model has been…

Methodology · Statistics 2025-05-27 Wenhao Li , Zhe Yin , Liang Li

In recent years, the growing availability of biomedical datasets featuring numerous longitudinal covariates has motivated the development of several multi-step methods for the dynamic prediction of survival outcomes. These methods employ…

Methodology · Statistics 2026-01-14 Mirko Signorelli , Sophie Retif

Growth mixture models are an important tool for detecting group structure in repeated measures data. Unlike traditional clustering methods, they explicitly model the repeat measurements on observations, and the statistical framework they…

Methodology · Statistics 2017-10-20 Abby Flynt , Nema Dean