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Advances in spatially-resolved transcriptomics (SRT) technologies have propelled the development of new computational analysis methods to unlock biological insights. As the cost of generating these data decreases, these technologies provide…
With nearly one million new cases diagnosed worldwide in 2020, head \& neck cancer is a deadly and common malignity. There are challenges to decision making and treatment of such cancer, due to lesions in multiple locations and outcome…
Quantitative Magnetic Resonance Imaging (qMRI) provides researchers insight into pathological and physiological alterations of living tissue, with the help of which researchers hope to predict (local) therapeutic efficacy early and…
A novel multi-focus image fusion algorithm performed in spatial domain based on similarity characteristics is proposed incorporating with region segmentation. In this paper, a new similarity measure is developed based on the structural…
In medical imaging, radiological scans of different modalities serve to enhance different sets of features for clinical diagnosis and treatment planning. This variety enriches the source information that could be used for outcome…
Central nervous system (CNS) tumors come with the vastly heterogeneous histologic, molecular and radiographic landscape, rendering their precise characterization challenging. The rapidly growing fields of biophysical modeling and radiomics…
Objectives: Analyze the types of studies and algorithms that are most applied, Identify the anatomical regions treated. Determine the application of parallel techniques used in studies carried out between 2010 and 2022 in research on noise…
Perfusion MRI (pMRI) offers valuable insights into tumor vascularity and promises to predict tumor genotypes, thus benefiting prognosis for glioma patients, yet effective models tailored to 4D pMRI are still lacking. This study presents the…
Background and Purpose: Voxel-based analysis (VBA) helps to identify dose-sensitive regions by aligning individual dose distributions within a common coordinate system (CCS). Accurate deformable image registration (DIR) is essential for…
Contemporary interventional imaging lacks the real-time 3D guidance needed for the precise localization of mobile thoracic targets. While Cone-Beam CT (CBCT) provides 3D data, it is often too slow for dynamic motion tracking. Deep learning…
Radiation therapy (RT) is essential in treating head and neck cancer (HNC), with magnetic resonance imaging(MRI)-guided RT offering superior soft tissue contrast and functional imaging. However, manual tumor segmentation is time-consuming…
Purpose: Tumor-associated vasculature differs from healthy blood vessels by its chaotic architecture and twistedness, which promotes treatment resistance. Measurable differences in these attributes may help stratify patients by likely…
Objective: Gadolinium-based contrast agents (GBCAs) are commonly used in MRI scans of patients with gliomas to enhance brain tumor characterization using T1-weighted (T1W) MRI. However, there is growing concern about GBCA toxicity. This…
Diagnosis of liver infection at preliminary stage is important for better treatment. In todays scenario devices like sensors are used for detection of infections. Accurate classification techniques are required for automatic identification…
Randomized Controlled Trials (RCTs) are the gold standard for comparing the effectiveness of a new treatment to the current one (the control). Most RCTs allocate the patients to the treatment group and the control group by uniform…
Head and neck squamous cell carcinoma (HNSCC) presents significant challenges in clinical oncology due to its heterogeneity and high mortality rates. This study aims to leverage clinical data and machine learning (ML) principles to predict…
Head and Neck (H\&N) organ-at-risk (OAR) and tumor segmentations are essential components of radiation therapy planning. The varying anatomic locations and dimensions of H\&N nodal Gross Tumor Volumes (GTVn) and H\&N primary gross tumor…
The variability introduced by differences in MRI scanner models, acquisition protocols, and imaging sites hinders consistent analysis and generalizability across multicenter studies. We present a novel image-based harmonization framework…
During and after a course of therapy, imaging is routinely used to monitor the disease progression and assess the treatment responses. Despite of its significance, reliably capturing and predicting the spatial-temporal anatomic changes from…
Epidemiology characterizes the influence of causes to disease and health conditions of defined populations. Cohort studies are population-based studies involving usually large numbers of randomly selected individuals and comprising numerous…