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Simulation of the dynamics of physical systems is essential to the development of both science and engineering. Recently there is an increasing interest in learning to simulate the dynamics of physical systems using neural networks.…

Machine Learning · Computer Science 2022-01-31 Ce Yang , Weihao Gao , Di Wu , Chong Wang

Optimizing chemical properties is a challenging task due to the vastness and complexity of chemical space. Here, we present a generative energy-based architecture for implicit chemical property optimization, designed to efficiently generate…

Biomolecules · Quantitative Biology 2025-06-19 Luca Miglior , Lorenzo Simone , Marco Podda , Davide Bacciu

This study proposes an approach toward the first principles electronic structure calculation with the aid of symbolic-numeric solving. The symbolic computation enables us to express the Hartree-Fock-Roothaan equation and the molecular…

Symbolic Computation · Computer Science 2013-02-26 Akihito Kikuchi

Shapley-related techniques have gained attention as both global and local interpretation tools because of their desirable properties. However, their computation using conditional expectations is computationally expensive. Approximation…

Machine Learning · Statistics 2022-07-13 Zhipu Zhou , Jie Chen , Linwei Hu

Determining the proper level of details to develop and solve physical models is usually difficult when one encounters new engineering problems. Such difficulty comes from how to balance the time (simulation cost) and accuracy for the…

Artificial Intelligence · Computer Science 2022-02-03 Randi Wang , Morad Behandish

Global optimisation problems in high-dimensional and infinite dimensional spaces arise in various real-world applications such as engineering, economics, geophysics, biology, machine learning, optimal control, etc. Among stochastic…

Optimization and Control · Mathematics 2021-01-06 Andrew Yu. Morozov , Oleg Kuzenkov , Simran K. Sandhu

A novel design optimization approach (ActivO) that employs an ensemble of machine learning algorithms is presented. The proposed approach is a surrogate-based scheme, where the predictions of a weak leaner and a strong learner are utilized…

Machine Learning · Computer Science 2021-01-06 Opeoluwa Owoyele , Pinaki Pal

Graph Masked Autoencoders (GMAEs) have emerged as a notable self-supervised learning approach for graph-structured data. Existing GMAE models primarily focus on reconstructing node-level information, categorizing them as single-scale GMAEs.…

Machine Learning · Computer Science 2026-03-19 Chuang Liu , Zelin Yao , Xueqi Ma , Mukun Chen , Luzhi Wang , Jia Wu , Wenbin Hu

Stochastic, iterative search methods such as Evolutionary Algorithms (EAs) are proven to be efficient optimizers. However, they require evaluation of the candidate solutions which may be prohibitively expensive in many real world…

Neural and Evolutionary Computing · Computer Science 2013-03-12 Maumita Bhattacharya

Both experimental and computational methods for the exploration of structure, functionality, and properties of materials often necessitate the search across broad parameter spaces to discover optimal experimental conditions and regions of…

Computational Physics · Physics 2021-08-31 Maxim Ziatdinov , Ayana Ghosh , Sergei V. Kalinin

Structure learning of Bayesian networks has always been a challenging problem. Nowadays, massive-size networks with thousands or more of nodes but fewer samples frequently appear in many areas. We develop a divide-and-conquer framework,…

Machine Learning · Statistics 2020-09-24 Jiaying Gu , Qing Zhou

This manuscript proposes an optimization framework to find the tailor-made functionally graded material (FGM) profiles for thermoelastic applications. This optimization framework consists of (1) a random profile generation scheme, (2) deep…

Computational Engineering, Finance, and Science · Computer Science 2024-08-27 Piyush Agrawal , Ihina Mahajan , Shivam Choubey , Manish Agrawal

A surrogate model approximates the outputs of a solver of Partial Differential Equations (PDEs) with a low computational cost. In this article, we propose a method to build learning-based surrogates in the context of parameterized PDEs,…

Machine Learning · Computer Science 2024-06-28 Alejandro Ribés , Nawfal Benchekroun , Théo Delagnes

Exploring molecular energy landscapes and identifying ground-state conformations are central challenges in computational chemistry. However, generating diverse low-energy conformers from molecular graphs remains expensive with traditional…

Machine Learning · Computer Science 2026-05-25 Guikun Xu , Xiaohan Yi , Ziqiao Meng , Peilin Zhao , Yatao Bian

Inverse design optimization aims to infer system parameters from observed solutions, posing critical challenges across domains such as semiconductor manufacturing, structural engineering, materials science, and fluid dynamics. The lack of…

Artificial Intelligence · Computer Science 2025-10-16 Haoyu Yang , Kamyar Azizzadenesheli , Haoxing Ren

Disordered materials such as glasses, unlike crystals, lack long range atomic order and have no periodic unit cells, yielding a high dimensional configuration space with widely varying properties. The complexity not only increases…

Computational Engineering, Finance, and Science · Computer Science 2025-11-12 Qiyuan Chen , Ajay Annamareddy , Ying-Fei Li , Dane Morgan , Bu Wang

The optimal power flow (OPF) problem, as a critical component of power system operations, becomes increasingly difficult to solve due to the variability, intermittency, and unpredictability of renewable energy brought to the power system.…

Machine Learning · Computer Science 2024-01-18 Yuxuan Li , Chaoyue Zhao , Chenang Liu

Numerical homogenization and multiscale finite element methods construct effective properties on a coarse grid by solving local problems and extracting the average effective properties from these local solutions. In some cases, the…

Numerical Analysis · Mathematics 2016-06-21 Eric T. Chung , Yalchin Efendiev , Wing Tat Leung , Maria Vasilyeva

The configuration of graphene (GE) sheet conforming to the spherical surface substrate is studied through theoretical model and molecular simulations. Two basic configurations are observed: fully conformation and wrinkling. The final…

Mesoscale and Nanoscale Physics · Physics 2015-12-15 Yanguang Zhou , Yuli Chen , Bin Liu , Zhenyu Yang , Ming Hu , Shengtao Wang , Zeshuai Yuan

An enhanced geothermal system is essential to provide sustainable and long-term geothermal energy supplies and reduce carbon emissions. Optimal well-control scheme for effective heat extraction and improved heat sweep efficiency plays a…

Neural and Evolutionary Computing · Computer Science 2022-12-20 Guodong Chen , Xin Luo , Chuanyin Jiang , Jiu Jimmy Jiao
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