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Many of the cell membrane vital functions are achieved by the self-organization of the proteins and biopolymers embedded in it. The protein dynamics are in part determined by its drag. A large number of these proteins can polymerize to form…

Fluid Dynamics · Physics 2023-09-13 Wenzheng Shi , Moslem Moradi , Ehssan Nazockdast

Reparameterized diffusion models (RDMs) have recently matched autoregressive methods in protein generation, motivating their use for challenging tasks such as designing membrane proteins, which possess interleaved soluble and transmembrane…

Biomolecules · Quantitative Biology 2025-09-30 Shrey Goel , Peregrine M. Schray , Yinuo Zhang , Sophia Vincoff , Huong T. Kratochvil , Pranam Chatterjee

The introduction of 'twist' or relative rotation between two atomically thin van der Waals (vdW) membranes gives rise to periodic Moire potential, leading to a substantial altercation of the band structure of the planar assembly. While most…

Mesoscale and Nanoscale Physics · Physics 2020-12-30 Phanibhusan S Mahapatra , Bhaskar Ghawri , Kenji Watanabe , Takashi Taniguchi , Subroto Mukerjee , Arindam Ghosh

Lipid vesicles consist of aqueous cores surrounded by a bilayer of phospholipids. Hybrid polymer-lipid vesicles incorporate both polymers and lipids, offering promising properties for developing pharmaceuticals, biosensors, and artificial…

The interplay of membrane proteins is vital for many biological processes, such as cellular transport, cell division, and signal transduction between nerve cells. Theoretical considerations have led to the idea that the membrane itself…

Soft Condensed Matter · Physics 2016-11-28 Casper van der Wel , Afshin Vahid , Anđela Šarić , Timon Idema , Doris Heinrich , Daniela J. Kraft

We present a novel laboratory setup for studying the fluid dynamics in liquid metal batteries (LMBs). LMBs are a promising technology suited for grid-scale energy storage, but flows remain a confounding factor in determining their…

Fluid Dynamics · Physics 2022-11-09 Jonathan S Cheng , Bitong Wang , Ibrahim Mohammad , Jarod M Forer , Douglas H Kelley

Biomembranes, primarily composed of lipid bilayers, are not merely passive barriers but dynamic and complex materials whose shapes are governed by the principles of soft matter physics. This review explores the shape problem in biomembranes…

Computational Physics · Physics 2026-05-05 Zhong-Can Ou-Yang , Tao Xu

Cholesterol plays an essential role in biological membranes and is crucial for maintaining their stability and functionality. It is necessary for a variety of membranes, including planar bilayers, liposomes, curved bilayers, nanodiscs, and…

Biomolecules · Quantitative Biology 2025-04-09 Ehsaneh Khodadadi , Ehsan Khodadadi , Parth Chaturvedi , Mahmoud Moradi

Blebs are balloon-shaped membrane protrusions that form during many physiological processes. Using computer simulation of a particle-based model for self-assembled lipid bilayers coupled to an elastic meshwork, we investigated the phase…

Biological Physics · Physics 2015-05-30 Eric J. Spangler , Cameron W. Harvey , Joel D. Revalee , P. B. Sunil Kumar , Mohamed Laradji

Thin cylindrical tethers are common lipid bilayer membrane structures, arising in situations ranging from micromanipulation experiments on artificial vesicles to the dynamic structure of the Golgi apparatus. We study the shape and formation…

Soft Condensed Matter · Physics 2009-11-07 Thomas R. Powers , Greg Huber , Raymond E. Goldstein

The fabrication of polyelectrolyte multilayer films (PEMs) using the Layer-by-Layer (LbL) method is one of the most versatile approaches for manufacturing functional surfaces. This is the result of the possibility to control the assembly…

Soft Condensed Matter · Physics 2024-02-08 Eduardo Guzman , Ramon G. Rubio , Francisco Ortega

We demonstrate by experiments and numerical simulations that the low-temperature current-voltage characteristics in diffusive bilayer graphene (BLG) exhibit a strong superlinearity at finite bias voltages. The superlinearity is weakly…

Mesoscale and Nanoscale Physics · Physics 2011-05-24 J. K. Viljas , A. Fay , M. Wiesner , P. J. Hakonen

We address the problem of antimicrobial peptides that create pores in lipid bilayers, focusing on voltage-temperature dependence of pore opening. Two novel experiments (voltage-clamp with alamethicin as an emblematic representative of these…

Soft Condensed Matter · Physics 2013-07-17 G. C. Fadda , D. Lairez , Z. Guennouni , A. Koutsioubas

We theoretically investigate a folded bilayer graphene structure as an experimentally realizable platform to produce the one-dimensional topological zero-line modes. We demonstrate that the folded bilayer graphene under an external gate…

Mesoscale and Nanoscale Physics · Physics 2018-12-26 Tao Hou , Guanghui Chen , Wang-Kong Tse , Changgan Zeng , Zhenhua Qiao

We use computer simulations and a simple free energy model to study the response of a bilayer membrane to the application of a negative (compressive) mechanical tension. Such a tension destabilizes the long wavelength undulation modes of…

Soft Condensed Matter · Physics 2015-06-24 Yotam Y. Avital , Oded Farago

Membrane bending is an extensively studied problem from both modeling and experimental perspectives because of the wide implications of curvature generation in cell biology. Many of the curvature generating aspects in membranes can be…

Soft Condensed Matter · Physics 2021-07-21 Arijit Mahapatra , David Saintillan , Padmini Rangamani

A mesoscopic coarse-grain model for computationally-efficient simulations of biomembranes is presented. It combines molecular dynamics simulations for the lipids, modeled as elastic chains of beads, with multiparticle collision dynamics for…

Soft Condensed Matter · Physics 2015-06-04 Mu-Jie Huang , Raymond Kapral , Alexander S. Mikhailov , Hsuan-Yi Chen

We present real-time observations by confocal microscopy of the dynamic behavior of multilamellar vesicles (MLVs), composed of charged synthetic lipids, when put in contact with oppositely charged polyelectrolyte (PE) molecules. We find…

Soft Condensed Matter · Physics 2007-10-01 Yuxia Luan , Laurence Ramos

We propose theoretical and numerical analyses of smart bending deformation of a dielectric-elastic bilayer in response to a voltage, based on the nonlinear theory of electro-elasticity and the associated linearized incremental field theory.…

Soft Condensed Matter · Physics 2019-07-30 Yipin Su , Bin Wu , Weiqiu Chen , Michel Destrade

We theoretically investigate the dynamics of a floating lipid bilayer membrane coupled with a two-dimensional cytoskeleton network, taking into explicitly account the intermonolayer friction, the discrete lattice structure of the…

Soft Condensed Matter · Physics 2017-08-02 Ryuichi Okamoto , Shigeyuki Komura , Jean-Baptiste Fournier
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