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This series presents an approach to mathematical biology which makes precise the function of biological molecules. Because biological systems compute, the theory is a general purpose computer language. I build a language for efficiently…

Molecular Networks · Quantitative Biology 2007-05-23 Ron Maimon

Human-centred systems require an understanding of human actions in the physical world. Temporally extended sequences of actions are intentional and structured, yet existing methods for recognising what actions are performed often do not…

Artificial Intelligence · Computer Science 2026-04-21 Rimvydas Rubavicius , Manisha Dubey , N. Siddharth , Subramanian Ramamoorthy

Due to the scarcity of quantitative details about biological phenomena, quantitative modeling in systems biology can be compromised, especially at the subcellular scale. One way to get around this is qualitative modeling because it requires…

Molecular Networks · Quantitative Biology 2019-03-22 Arnaud Poret , Claudio Monteiro Sousa , Jean-Pierre Boissel

Information exchange is a critical process in all communication systems, including biological ones. The concept of retroactivity represents the loads that downstream modules apply to their upstream systems in biological circuits. This paper…

Emerging Technologies · Computer Science 2021-08-13 Francesca Ratti , Maurizio Magarini , Domitilla Del Vecchio

Although models are built on the basis of some observations of reality, the concepts that derive theoretically from their definitions as well as from their characteristics and properties are not necessarily direct consequences of these…

Discrete Mathematics · Computer Science 2011-11-11 Mathilde Noual , Sylvain Sené

The control of Biomedical Systems in Physical Human-Robot Interaction (pHRI) plays a pivotal role in achieving the desired behavior by ensuring the intended transfer function and stability of subsystems within the overall system.…

Logic in Computer Science · Computer Science 2025-01-03 Adnan Rashid , Sa'ed Abed , Osman Hasan

The paper describes multistage design of composite (modular) systems (i.e., design of a system trajectory). This design process consists of the following: (i) definition of a set of time/logical points; (ii) modular design of the system for…

Artificial Intelligence · Computer Science 2013-06-20 Mark Sh. Levin

Explanations of model behavior are commonly evaluated via proxy properties weakly tied to the purposes explanations serve in practice. We contribute a decision theoretic framework that treats explanations as information signals valued by…

Artificial Intelligence · Computer Science 2026-02-24 Ziyang Guo , Berk Ustun , Jessica Hullman

We propose a method of classifying the operation of a system into finitely many modes. Each mode has its own objectives for the system's behaviour and its own mathematical models and algorithms designed to accomplish its objectives. A…

Logic in Computer Science · Computer Science 2021-07-14 Edwin Beggs , John V. Tucker

Understanding the mechanisms of interactions within cells, tissues, and organisms is crucial to driving developments across biology and medicine. Mathematical modeling is an essential tool for simulating biological systems and revealing…

Molecular Networks · Quantitative Biology 2024-08-13 Lingxia Qiao , Ali Khalilimeybodi , Nathaniel J Linden-Santangeli , Padmini Rangamani

Identifying and understanding modular organizations is centrally important in the study of complex systems. Several approaches to this problem have been advanced, many framed in information-theoretic terms. Our treatment starts from the…

Adaptation and Self-Organizing Systems · Physics 2015-01-19 Artemy Kolchinsky , Luis M. Rocha

We present work on behavioral specifications of OSGi components. Our behavioral specifications are based on finite automata like formalisms. Behavioral specifications can be used to find appropriate components to interact with, detect…

Software Engineering · Computer Science 2013-02-22 Jan Olaf Blech

Complex robot behaviour typically requires the integration of multiple robotic and Artificial Intelligence (AI) techniques and components. Integrating such disparate components into a coherent system, while also ensuring global properties…

Artificial Intelligence · Computer Science 2023-10-20 Bernhard Hengst , Maurice Pagnucco , David Rajaratnam , Claude Sammut , Michael Thielscher

This paper is a first step to chase the ambitious objective of developing a mathmatical theory of living systems. The contents refer modeling large systems of interacting living entities with the aim of describing their collective behaviors…

This paper focuses on the identification of dynamical systems with tailor-made model structures, where neural networks are used to approximate uncertain components and domain knowledge is retained, if available. These model structures are…

Machine Learning · Computer Science 2021-10-29 Marco Forgione , Dario Piga

Metabolic networks consist of linked functional components, or modules. The mechanism underlying metabolic network modularity is of great interest not only to researchers of basic science but also to those in fields of engineering. Previous…

Molecular Networks · Quantitative Biology 2012-09-14 Kazuhiro Takemoto

In this paper an efficient model based diagnostic process is described for systems whose components possess a causal relation between their inputs and their outputs. In this diagnostic process, firstly, a set of focuses on likely broken…

Artificial Intelligence · Computer Science 2022-09-21 Nico Roos

The ubiquity of modules in biological networks may result from an evolutionary benefit of a modular organization. For instance, modularity may increase the rate of adaptive evolution, because modules can be easily combined into new…

Molecular Networks · Quantitative Biology 2011-08-26 Areejit Samal , Andreas Wagner , Olivier C. Martin

Enterprise modeling deals with the increasing complexity of processes and systems by operationalizing model content and by linking complementary models and languages, thus amplifying the model-value beyond mere comprehensible pictures. To…

Software Engineering · Computer Science 2022-03-29 Victoria Döller

We propose a methodology for verifying security properties of network protocols at design level. It can be separated in two main parts: context and requirements analysis and informal verification; and formal representation and procedural…

Cryptography and Security · Computer Science 2013-10-29 Jesus Diaz , David Arroyo , Francisco B. Rodriguez
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