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A large number of surface-based analyses on brain imaging data adopt some specific brain atlases to better assess structural and functional changes in one or more brain regions. In these analyses, it is necessary to obtain an anatomically…

Image and Video Processing · Electrical Eng. & Systems 2019-10-01 Wen Zhang , Yalin Wang

Neuronal cell bodies mostly reside in the cerebral cortex. The study of this thin and highly convoluted surface is essential for understanding how the brain works. The analysis of surface data is, however, challenging due to the high…

Computer Vision and Pattern Recognition · Computer Science 2018-03-29 Karthik Gopinath , Christian Desrosiers , Herve Lombaert

The reconstruction of cerebral cortex surfaces from brain MRI scans is instrumental for the analysis of brain morphology and the detection of cortical thinning in neurodegenerative diseases like Alzheimer's disease (AD). Moreover, for a…

Neurons and Cognition · Quantitative Biology 2022-10-05 Anne-Marie Rickmann , Fabian Bongratz , Sebastian Pölsterl , Ignacio Sarasua , Christian Wachinger

Cortical surface registration is a fundamental tool for neuroimaging analysis that has been shown to improve the alignment of functional regions relative to volumetric approaches. Classically, image registration is performed by optimizing a…

Computer Vision and Pattern Recognition · Computer Science 2022-03-25 Mohamed A. Suliman , Logan Z. J. Williams , Abdulah Fawaz , Emma C. Robinson

The analysis of the brain surface modeled as a graph mesh is a challenging task. Conventional deep learning approaches often rely on data lying in the Euclidean space. As an extension to irregular graphs, convolution operations are defined…

Image and Video Processing · Electrical Eng. & Systems 2019-11-25 Ran He , Karthik Gopinath , Christian Desrosiers , Herve Lombaert

Non-rigid cortical registration is an important and challenging task due to the geometric complexity of the human cortex and the high degree of inter-subject variability. A conventional solution is to use a spherical representation of…

Image and Video Processing · Electrical Eng. & Systems 2020-07-28 Jieyu Cheng , Adrian V. Dalca , Bruce Fischl , Lilla Zollei

We present a hybrid method that performs the complete parcellation of the cerebral cortex of an individual, based on the connectivity information of the white matter fibers from a whole-brain tractography dataset. The method consists of…

Neurons and Cognition · Quantitative Biology 2020-02-24 Narciso López-López , Andrea Vázquez , Cyril Poupon , Jean-François Mangin , Pamela Guevara

Microscopic analysis of histological sections is considered the "gold standard" to verify structural parcellations in the human brain. Its high resolution allows the study of laminar and columnar patterns of cell distributions, which build…

Computer Vision and Pattern Recognition · Computer Science 2017-08-01 Hannah Spitzer , Katrin Amunts , Stefan Harmeling , Timo Dickscheid

Convolutional Neural Networks (CNNs) have been providing the state-of-the-art performance for learning-related problems involving 2D/3D images in Euclidean space. However, unlike in the Euclidean space, the shapes of many structures in…

Computer Vision and Pattern Recognition · Computer Science 2019-04-02 Fenqiang Zhao , Shunren Xia , Zhengwang Wu , Dingna Duan , Li Wang , Weili Lin , John H Gilmore , Dinggang Shen , Gang Li

Currently, cortical surface registration techniques based on classical methods have been well developed. However, a key issue with classical methods is that for each pair of images to be registered, it is necessary to search for the optimal…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Ruoyu Zhang , Lihui Wang , Kun Tang , Jingwen Xu , Hongjiang Wei

Cortical surface parcellation is a fundamental task in both basic neuroscience research and clinical applications, enabling more accurate mapping of brain regions. Model-based and learning-based approaches for automated parcellation…

Neurons and Cognition · Quantitative Biology 2025-12-30 Jian Li , Karthik Gopinath , Brian L. Edlow , Adrian V. Dalca , Bruce Fischl

In this thesis, we present robust and fully-automated methods for the subdivision of the entire human cerebral cortex based on connectivity information. Our contributions are four-fold: First, we propose a clustering approach to delineate a…

Neurons and Cognition · Quantitative Biology 2018-02-21 Salim Arslan

The task of automatically segmenting 3-D surfaces representing boundaries of objects is important for quantitative analysis of volumetric images, and plays a vital role in biomedical image analysis. Recently, graph-based methods with a…

Computer Vision and Pattern Recognition · Computer Science 2018-01-10 Abhay Shah , Michael Abramoff , Xiaodong Wu

Deep convolutional neural networks are powerful tools for learning visual representations from images. However, designing efficient deep architectures to analyse volumetric medical images remains challenging. This work investigates…

Computer Vision and Pattern Recognition · Computer Science 2017-07-10 Wenqi Li , Guotai Wang , Lucas Fidon , Sebastien Ourselin , M. Jorge Cardoso , Tom Vercauteren

One of the primary objectives of human brain mapping is the division of the cortical surface into functionally distinct regions, i.e. parcellation. While it is generally agreed that at macro-scale different regions of the cortex have…

Neurons and Cognition · Quantitative Biology 2017-03-06 Daniel Moyer , Boris A Gutman , Neda Jahanshad , Paul M. Thompson

Surface analysis of the cortex is ubiquitous in human neuroimaging with MRI, e.g., for cortical registration, parcellation, or thickness estimation. The convoluted cortical geometry requires isotropic scans (e.g., 1mm MPRAGEs) and good…

Image and Video Processing · Electrical Eng. & Systems 2023-05-04 Karthik Gopinath , Douglas N. Greve , Sudeshna Das , Steve Arnold , Colin Magdamo , Juan Eugenio Iglesias

Cortical surface reconstruction (CSR) from MRI is key to investigating brain structure and function. While recent deep learning approaches have significantly improved the speed of CSR, a substantial amount of runtime is still needed to map…

Image and Video Processing · Electrical Eng. & Systems 2023-12-12 Xiaoyang Chen , Junjie Zhao , Siyuan Liu , Sahar Ahmad , Pew-Thian Yap

Brain surface analysis is essential to neuroscience, however, the complex geometry of the brain cortex hinders computational methods for this task. The difficulty arises from a discrepancy between 3D imaging data, which is represented in…

Computer Vision and Pattern Recognition · Computer Science 2019-11-25 Karthik Gopinath , Christian Desrosiers , Herve Lombaert

Charting cortical growth trajectories is of paramount importance for understanding brain development. However, such analysis necessitates the collection of longitudinal data, which can be challenging due to subject dropouts and failed…

Computer Vision and Pattern Recognition · Computer Science 2020-09-15 Peirong Liu , Zhengwang Wu , Gang Li , Pew-Thian Yap , Dinggang Shen

Fetal cortical plate segmentation is essential in quantitative analysis of fetal brain maturation and cortical folding. Manual segmentation of the cortical plate, or manual refinement of automatic segmentations is tedious and…

Computer Vision and Pattern Recognition · Computer Science 2021-04-05 Haoran Dou , Davood Karimi , Caitlin K. Rollins , Cynthia M. Ortinau , Lana Vasung , Clemente Velasco-Annis , Abdelhakim Ouaalam , Xin Yang , Dong Ni , Ali Gholipour
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