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Causal inference in modern largescale systems faces growing challenges, including highdimensional covariates, multi-valued treatments, massive observational (OBS) data, and limited randomized controlled trial (RCT) samples due to cost…

Methodology · Statistics 2026-02-27 Yuxi Du , Zhiheng Zhang , Haoxuan Li , Cong Fang , Jixing Xu , Peng Zhen , Jiecheng Guo

I argue that regularizing terms in standard regression methods not only help against overfitting finite data, but sometimes also yield better causal models in the infinite sample regime. I first consider a multi-dimensional variable…

Machine Learning · Statistics 2019-07-01 Dominik Janzing

In this paper we demonstrate that two common problems in Machine Learning---imbalanced and overlapping data distributions---do not have independent effects on the performance of SVM classifiers. This result is notable since it shows that a…

Artificial Intelligence · Computer Science 2011-09-19 Misha Denil , Thomas Trappenberg

Purpose: Development of a novel interactive visualization approach for the exploration of radiotherapy treatment plans with a focus on overlap volumes with the aim of healthy tissue sparing. Methods: We propose a visualization approach to…

Human-Computer Interaction · Computer Science 2023-10-03 Matthias Schlachter , Samuel Peters , Daniel Camenisch , Paul Martin Putora , Katja Bühler

We study optimal procedures for estimating a linear functional based on observational data. In many problems of this kind, a widely used assumption is strict overlap, i.e., uniform boundedness of the importance ratio, which measures how…

Statistics Theory · Mathematics 2023-01-18 Wenlong Mou , Peng Ding , Martin J. Wainwright , Peter L. Bartlett

Inferring causal effects from an observational study is challenging because participants are not randomized to treatment. Observational studies in infectious disease research present the additional challenge that one participant's treatment…

Methodology · Statistics 2020-12-25 Brian G. Barkley , Michael G. Hudgens , John D. Clemens , Mohammad Ali , Michael E. Emch

The first step in evaluating a potential diagnostic biomarker is to examine the variation in its values across different disease groups. In a three-class disease setting, the volume under the receiver operating characteristic surface and…

Methodology · Statistics 2025-04-18 Zhaoxi Zhang , Vanda Inacio , Miguel de Carvalho

Over the past ten years, propensity score methods have made an important contribution to improving generalizations from studies that do not select samples randomly from a population of inference. However, these methods require assumptions…

Methodology · Statistics 2021-01-26 Wendy Chan

In this paper we study the problems of estimating heterogeneity in causal effects in experimental or observational studies and conducting inference about the magnitude of the differences in treatment effects across subsets of the…

Machine Learning · Statistics 2022-06-08 Susan Athey , Guido Imbens

We consider a causal inference model in which individuals interact in a social network and they may not comply with the assigned treatments. In particular, we suppose that the form of network interference is unknown to researchers. To…

Methodology · Statistics 2023-10-24 Tadao Hoshino , Takahide Yanagi

The identification of causal effects in observational studies typically relies on two standard assumptions: unconfoundedness and overlap. However, both assumptions are often questionable in practice: unconfoundedness is inherently…

Methodology · Statistics 2025-09-17 Han Cui , Xinran Li

Subword tokenizers trained on multilingual corpora naturally produce overlapping tokens across languages. Does token overlap facilitate cross-lingual transfer or instead introduce interference between languages? Prior work offers mixed…

Computation and Language · Computer Science 2025-09-26 Julie Kallini , Dan Jurafsky , Christopher Potts , Martijn Bartelds

This paper deals with the problem of evaluating the causal effect using observational data in the presence of an unobserved exposure/ outcome variable, when cause-effect relationships between variables can be described as a directed acyclic…

Methodology · Statistics 2012-06-18 Manabu Kuroki , Zhihong Cai

Researchers are often challenged with assessing the impact of an intervention on an outcome of interest in situations where the intervention is non-randomised, the intervention is only applied to one or few units, the intervention is…

Estimating causal effects is vital for decision making. In standard causal effect estimation, treatments are usually binary- or continuous-valued. However, in many important real-world settings, treatments can be structured,…

Machine Learning · Statistics 2024-12-02 Oriol Corcoll Andreu , Athanasios Vlontzos , Michael O'Riordan , Ciaran M. Gilligan-Lee

A treatment benefit predictor (TBP) is a function that maps patient characteristics to an estimate of the treatment benefit for that patient. Such predictors support optimizing individualized treatment decisions, which are central to…

Methodology · Statistics 2025-09-30 Yuan Xia , Mohsen Sadatsafavi , Paul Gustafson

In this paper we present a new measure for the overlap of two density functions which provides motivation and interpretation currently lacking with benchmark measures based on the proportion of similar response, also known as the overlap…

Methodology · Statistics 2021-06-08 Stephen G Walker

When assessing causal effects, determining the target population to which the results are intended to generalize is a critical decision. Randomized and observational studies each have strengths and limitations for estimating causal effects…

Methodology · Statistics 2022-10-21 Irina Degtiar , Sherri Rose

This paper proposes an easy-to-compute upper bound for the overlap index between two probability distributions without requiring any knowledge of the distribution models. The computation of our bound is time-efficient and memory-efficient…

Machine Learning · Computer Science 2024-12-02 Hao Fu , Prashanth Krishnamurthy , Siddharth Garg , Farshad Khorrami

Observational studies of causal effects require adjustment for confounding factors. In the tabular setting, where these factors are well-defined, separate random variables, the effect of confounding is well understood. However, in public…

Machine Learning · Computer Science 2023-02-16 Connor T. Jerzak , Fredrik Johansson , Adel Daoud