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The instance segmentation can be considered an extension of the object detection problem where bounding boxes are replaced by object contours. Strictly speaking the problem requires to identify each pixel instance and class independently of…

Computer Vision and Pattern Recognition · Computer Science 2017-11-27 Thomio Watanabe , Denis Wolf

Nucleus segmentation and classification are the prerequisites in the workflow of digital pathology processing. However, it is very challenging due to its high-level heterogeneity and wide variations. This work proposes a deep neural network…

Image and Video Processing · Electrical Eng. & Systems 2022-12-07 Sen Yang , Jinxi Xiang , Xiyue Wang

Nuclei segmentation is both an important and in some ways ideal task for modern computer vision methods, e.g. convolutional neural networks. While recent developments in theory and open-source software have made these tools easier to…

Computer Vision and Pattern Recognition · Computer Science 2019-01-30 Aarno Oskar Vuola , Saad Ullah Akram , Juho Kannala

Every year millions of people die due to disease of Cancer. Due to its invasive nature it is very complex to cure even in primary stages. Hence, only method to survive this disease completely is via forecasting by analyzing the early…

Computer Vision and Pattern Recognition · Computer Science 2018-08-24 Shivam Singh , Stuti Pathak

Automatic segmentation of microscopy images is an important task in medical image processing and analysis. Nucleus detection is an important example of this task. Mask-RCNN is a recently proposed state-of-the-art algorithm for object…

Computer Vision and Pattern Recognition · Computer Science 2021-04-01 Jeremiah W. Johnson

Nuclear segmentation in histology images is a challenging task due to significant variations in the shape and appearance of nuclei. One of the main hurdles in nuclear instance segmentation is overlapping nuclei where a smart algorithm is…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Navid Alemi Koohbanani , Mostafa Jahanifar , Ali Gooya , Nasir Rajpoot

Quantitative analysis of cell nuclei in microscopic images is an essential yet challenging source of biological and pathological information. The major challenge is accurate detection and segmentation of densely packed nuclei in images…

Quantitative Methods · Quantitative Biology 2019-11-14 Linqing Feng , Jun Ho Song , Jiwon Kim , Soomin Jeong , Jin Sung Park , Jinhyun Kim

Microscopy structure segmentation, such as detecting cells or nuclei, generally requires a human to draw a ground truth contour around each instance. Weakly supervised approaches (e.g. consisting of only single point labels) have the…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 James Willoughby , Irina Voiculescu

In computational pathology, nuclear instance segmentation is a fundamental task with many downstream clinical applications. With the advent of deep learning, many approaches, including convolutional neural networks (CNNs) and vision…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Amirreza Mahbod , Ramona Woitek , Jeanne Shen

Deep learning-based methods are gaining traction in digital pathology, with an increasing number of publications and challenges that aim at easing the work of systematically and exhaustively analyzing tissue slides. These methods often…

Image and Video Processing · Electrical Eng. & Systems 2020-06-25 Ting-An Yen , Hung-Chun Hsu , Pushpak Pati , Maria Gabrani , Antonio Foncubierta-Rodríguez , Pau-Choo Chung

Nuclei instance segmentation on histopathology images is of great clinical value for disease analysis. Generally, fully-supervised algorithms for this task require pixel-wise manual annotations, which is especially time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Yang Zhou , Yongjian Wu , Zihua Wang , Bingzheng Wei , Maode Lai , Jianzhong Shou , Yubo Fan , Yan Xu

Nuclear segmentation is an important step for profiling aberrant regions of histology sections. However, segmentation is a complex problem as a result of variations in nuclear geometry (e.g., size, shape), nuclear type (e.g., epithelial,…

Computer Vision and Pattern Recognition · Computer Science 2018-02-16 Mina Khoshdeli , Bahram Parvin

Separating and labeling each instance of a nucleus (instance-aware segmentation) is the key challenge in segmenting single cell nuclei on fluorescence microscopy images. Deep Neural Networks can learn the implicit transformation of a…

Computer Vision and Pattern Recognition · Computer Science 2021-08-11 Florian Kromp , Lukas Fischer , Eva Bozsaky , Inge Ambros , Wolfgang Doerr , Sabine Taschner-Mandl , Peter Ambros , Allan Hanbury

We propose an approach to instance-level image segmentation that is built on top of category-level segmentation. Specifically, for each pixel in a semantic category mask, its corresponding instance bounding box is predicted using a deep…

Computer Vision and Pattern Recognition · Computer Science 2016-05-24 Zifeng Wu , Chunhua Shen , Anton van den Hengel

Pre-trained on a large and diverse dataset, the segment anything model (SAM) is the first promptable foundation model in computer vision aiming at object segmentation tasks. In this work, we evaluate SAM for the task of nuclear instance…

Image and Video Processing · Electrical Eng. & Systems 2024-01-26 Kesi Xu , Lea Goetz , Nasir Rajpoot

Weakly supervised nuclei segmentation is a critical problem for pathological image analysis and greatly benefits the community due to the significant reduction of labeling cost. Adopting point annotations, previous methods mostly rely on…

Image and Video Processing · Electrical Eng. & Systems 2022-02-14 Weizhen Liu , Qian He , Xuming He

Nuclei segmentation is a fundamental task in digital pathology analysis and can be automated by deep learning-based methods. However, the development of such an automated method requires a large amount of data with precisely annotated masks…

Computer Vision and Pattern Recognition · Computer Science 2021-11-25 Jiangbo Shi , Chang Jia , Zeyu Gao , Tieliang Gong , Chunbao Wang , Chen Li

In this paper, we focus on improving binary 2D instance segmentation to assist humans in labeling ground truth datasets with polygons. Humans labeler just have to draw boxes around objects, and polygons are generated automatically. To be…

Computer Vision and Pattern Recognition · Computer Science 2022-08-25 Darshan Ganganna Ravindra , Laslo Dinges , Al-Hamadi Ayoub , Vasili Baranau

Automatic instance segmentation is a problem that occurs in many biomedical applications. State-of-the-art approaches either perform semantic segmentation or refine object bounding boxes obtained from detection methods. Both suffer from…

Computer Vision and Pattern Recognition · Computer Science 2020-04-22 Long Chen , Martin Strauch , Dorit Merhof

A major obstacle in instance segmentation is that existing methods often need many per-pixel labels in order to be effective. These labels require large human effort and for certain applications, such labels are not readily available. To…

Computer Vision and Pattern Recognition · Computer Science 2019-07-03 Issam H. Laradji , David Vazquez , Mark Schmidt
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