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Related papers: Aggregating Knockoffs for False Discovery Rate Con…

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The knockoff filter, recently developed by Barber and Candes, is an effective procedure to perform variable selection with a controlled false discovery rate (FDR). We propose a private version of the knockoff filter by incorporating…

Machine Learning · Statistics 2022-02-01 Mehrdad Pournaderi , Yu Xiang

A key assumption in most existing works on FL algorithms' convergence analysis is that the noise in stochastic first-order information has a finite variance. Although this assumption covers all light-tailed (i.e., sub-exponential) and some…

Machine Learning · Computer Science 2022-12-27 Haibo Yang , Peiwen Qiu , Jia Liu

Extracting associations that recur across multiple studies while controlling the false discovery rate is a fundamental challenge. Here, we consider an extension of Efron's single-study two-groups model to allow joint analysis of multiple…

Methodology · Statistics 2019-01-14 David Amar , Ron Shamir , Daniel Yekutieli

Estimating local false discovery rates (fdr) is central to large-scale multiple hypothesis testing, yet different methods often produce divergent results, and there is little guidance for selecting among them. Because ground truth…

Methodology · Statistics 2025-09-17 Jenna M. Landy , Giovanni Parmigiani

Motivated by the gene co-expression pattern analysis, we propose a novel sample quantile-based contingency (squac) statistic to infer quantile associations conditioning on covariates. It features enhanced flexibility in handling variables…

Methodology · Statistics 2018-08-27 Jichun Xie , Ruosha Li

The family-wise error rate (FWER) has been widely used in genome-wide association studies. With the increasing availability of functional genomics data, it is possible to increase the detection power by leveraging these genomic functional…

Methodology · Statistics 2020-12-25 Huijuan Zhou , Xianyang Zhang , Jun Chen

We run stochastic simulations of the spatial version of the rock-paper-scissors game, considering that individuals use sensory abilities to scan the environment to detect the presence of enemies. If the local dangerousness level is above a…

Populations and Evolution · Quantitative Biology 2023-05-04 J. Menezes , E. Rangel

Consider the problem of testing multiple null hypotheses. A classical approach to dealing with the multiplicity problem is to restrict attention to procedures that control the familywise error rate ($FWER$), the probability of even one…

Statistics Theory · Mathematics 2007-06-13 Joseph P. Romano , Azeem M. Shaikh

Genome-wide association studies (GWAS) have led to the discovery of numerous single nucleotide polymorphisms (SNPs) associated with various phenotypes and complex diseases. However, the identified genetic variants do not fully explain the…

Methodology · Statistics 2025-07-09 Dayeon Jung , Yewon Kim , Junyong Park

We present a new method based on Functional Data Analysis (FDA) for detecting associations between one or more scalar covariates and a longitudinal response, while correcting for other variables. Our methods exploit the temporal structure…

Applications · Statistics 2014-04-30 Matthew Reimherr , Dan Nicolae

Feature selection prepares the AI-readiness of data by eliminating redundant features. Prior research falls into two primary categories: i) Supervised Feature Selection, which identifies the optimal feature subset based on their relevance…

Machine Learning · Computer Science 2024-03-08 Xinyuan Wang , Dongjie Wang , Wangyang Ying , Rui Xie , Haifeng Chen , Yanjie Fu

For large-scale testing with graph-associated data, we present an empirical Bayes mixture technique to score local false discovery rates. Compared to empirical Bayes procedures that ignore the graph, the proposed method gains power in…

Methodology · Statistics 2019-11-26 TIen Vo , Vamsi Ithapu , Vikas Singh , Michael A. Newton

Consider the multiple testing problem of testing null hypotheses $H_1,...,H_s$. A classical approach to dealing with the multiplicity problem is to restrict attention to procedures that control the familywise error rate ($\mathit{FWER}$),…

Statistics Theory · Mathematics 2007-06-13 Joseph P. Romano , Azeem M. Shaikh

In this paper, we present novel methodologies that incorporate auxiliary variables for multiple hypotheses testing related to the main point of interest while effectively controlling the false discovery rate. When dealing with multiple…

Methodology · Statistics 2026-02-23 Seohwa Hwang , Mark Louie Ramos , DoHwan Park , Junyong Park , Johan Lim , Erin Green

Factor-adjusted multiple testing is used for handling strong correlated tests. Since most of previous works control the false discovery rate under sparse alternatives, we develop a two-step method, namely the AdaFAT, for any true false…

Statistics Theory · Mathematics 2020-11-03 Mengkun Du , Lan Wu

This paper introduces a novel Knockoff-guided compressive sensing framework, referred to as \TheName{}, which enhances signal recovery by leveraging precise false discovery rate (FDR) control during the support identification phase. Unlike…

Machine Learning · Statistics 2025-06-02 Xiaochen Zhang , Haoyi Xiong

In this article, we propose a novel strategy for conducting variable selection without prior model topology knowledge using the knockoff method with boosted tree models. Our method is inspired by the original knockoff method, where the…

Methodology · Statistics 2020-02-24 Tao Jiang , Yuanyuan Li , Alison A. Motsinger-Reif

Microbiota profiles measure the structure of microbial communities in a defined environment (known as microbiomes). In the past decade, microbiome research has focused on health applications as a result of which the gut microbiome has been…

Quantitative Methods · Quantitative Biology 2021-05-11 Benjamin Wingfield , Sonya Coleman , T. M. McGinnity , Anthony J. Bjourson

Obesity is a critical global health issue driven by dietary, physiological, and environmental factors, and is strongly associated with chronic diseases such as diabetes, cardiovascular disorders, and cancer. Machine learning has emerged as…

Machine Learning · Computer Science 2026-05-11 Towhidul Islam , Md Sumon Ali

Current backdoor attacks against federated learning (FL) strongly rely on universal triggers or semantic patterns, which can be easily detected and filtered by certain defense mechanisms such as norm clipping, comparing parameter…

Machine Learning · Computer Science 2023-10-02 Yanqi Qiao , Dazhuang Liu , Congwen Chen , Rui Wang , Kaitai Liang