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We present a physics-informed deep learning framework to address common limitations in Confocal Laser Scanning Microscopy (CLSM), such as diffraction limited resolution, noise, and undersampling due to low laser power conditions. The…

Materials Science · Physics 2025-01-27 Zaheer Ahmad , Junaid Shabeer , Usman Saleem , Tahir Qadeer , Abdul Sami , Zahira El Khalidi , Saad Mehmood

We present a simple and effective approach for non-blind image deblurring, combining classical techniques and deep learning. In contrast to existing methods that deblur the image directly in the standard image space, we propose to perform…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Jiangxin Dong , Stefan Roth , Bernt Schiele

Fluorescence microscopy images usually show severe anisotropy in axial versus lateral resolution. This hampers downstream processing, i.e. the automatic extraction of quantitative biological data. While deconvolution methods and other…

Computer Vision and Pattern Recognition · Computer Science 2017-04-06 Martin Weigert , Loic Royer , Florian Jug , Gene Myers

Anisoplanatic effects can cause significant systematic photometric uncertainty in the analysis of dense stellar fields observed with adaptive optics. Program packages have been developed for a spatially variable PSF, but they require that a…

Instrumentation and Methods for Astrophysics · Physics 2009-12-08 R. Schoedel

Light-field microscopy (LFM) enables rapid volumetric imaging through single-frame acquisition and fast 3D reconstruction algorithms. The high speed and low phototoxicity of LFM make it highly suitable for real-time 3D fluorescence imaging,…

Optics · Physics 2025-02-24 Bohan Qu , Zhouyu Jin , You Zhou , Bo Xiong , Xun Cao

In this paper, we address the task of aberration-aware depth-from-defocus (DfD), which takes account of spatially variant point spread functions (PSFs) of a real camera. To effectively obtain the spatially variant PSFs of a real camera…

Computer Vision and Pattern Recognition · Computer Science 2024-02-29 Zhuofeng Wu , Yusuke Monno , Masatoshi Okutomi

Deep neural networks have been applied to improve the image quality of fluorescence microscopy imaging. Previous methods are based on convolutional neural networks (CNNs) which generally require more time-consuming training of separate…

Point-spread function (PSF) estimation in spatially undersampled images is challenging because large pixels average fine-scale spatial information. This is problematic when fine-resolution details are necessary, as in optimal photometry…

Instrumentation and Methods for Astrophysics · Physics 2021-02-03 Teresa Symons , Michael Zemcov , James Bock , Yun-Ting Cheng , Brendan Crill , Christopher Hirata , Stephanie Venuto

Pre-trained vision foundation models (VFMs) provide strong semantic representations, yet their patch-level features are inherently coarse, limiting their effectiveness on tasks requiring fine-grained localization, dense prediction, and…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Wentong Li , Zhiyuan Qi , Zichen Zhao , Kai Zhang , Lei Zhang

We present a variational Bayesian method of joint image reconstruction and point spread function (PSF) estimation when the PSF of the imaging device is only partially known. To solve this semi-blind deconvolution problem, prior…

Data Analysis, Statistics and Probability · Physics 2013-03-18 Se Un Park , Nicolas Dobigeon , Alfred O. Hero

Recycled and recirculated books, such as ancient texts and reused textbooks, hold significant value in the second-hand goods market, with their worth largely dependent on surface preservation. However, accurately assessing surface defects…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Jun Yu , WenJian Wang

Image super-resolution is a challenging task and has attracted increasing attention in research and industrial communities. In this paper, we propose a novel end-to-end Attention-based DenseNet with Residual Deconvolution named as ADRD. In…

Computer Vision and Pattern Recognition · Computer Science 2019-07-12 Zhuangzi Li

This paper demonstrates a practical method that can correct spatial varying blur from a set of images of the same object. The algorithm jointly estimates the object and local point spread functions~(PSF). The method prioritizes sections…

Image and Video Processing · Electrical Eng. & Systems 2020-11-04 Wouter van de Ketterij , Oleg Soloviev , Michel Verhaegen

Purpose: To develop an algorithm for robust partial Fourier (PF) reconstruction applicable to diffusion-weighted (DW) images with non-smooth phase variations. Methods: Based on an unrolled proximal splitting algorithm, a neural network…

Image and Video Processing · Electrical Eng. & Systems 2022-01-11 Fasil Gadjimuradov , Thomas Benkert , Marcel Dominik Nickel , Andreas Maier

Majority of deep learning methods utilize vanilla convolution for enhancing underwater images. While vanilla convolution excels in capturing local features and learning the spatial hierarchical structure of images, it tends to smooth input…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Song Zhang , Daoliang Li , Ran Zhao

To leverage deep learning for image aesthetics assessment, one critical but unsolved issue is how to seamlessly incorporate the information of image aspect ratios to learn more robust models. In this paper, an adaptive fractional dilated…

Computer Vision and Pattern Recognition · Computer Science 2020-04-08 Qiuyu Chen , Wei Zhang , Ning Zhou , Peng Lei , Yi Xu , Yu Zheng , Jianping Fan

One of the major limitations of adaptive optics (AO) corrected image post-processing is the lack of knowledge on the system point spread function (PSF). The PSF is not always available as a direct imaging on isolated point like objects such…

Instrumentation and Methods for Astrophysics · Physics 2020-07-22 Romain Fétick , Laurent Mugnier , Thierry Fusco , Benoit Neichel

Removing the aberrations introduced by the Point Spread Function (PSF) is a fundamental aspect of astronomical image processing. The presence of noise in observed images makes deconvolution a nontrivial task that necessitates the use of…

Instrumentation and Methods for Astrophysics · Physics 2017-05-03 Samuel Farrens , Jean-Luc Starck , Fred Maurice Ngolè Mboula

For conventional computed tomography (CT) image reconstruction tasks, the most popular method is the so-called filtered-back-projection (FBP) algorithm. In it, the acquired Radon projections are usually filtered first by a ramp kernel…

Medical Physics · Physics 2018-07-06 Yongshuai Ge , Qiyang Zhang , Zhanli Hu , Jianwei Chen , Wei Shi , Hairong Zheng , Dong Liang

Existing shape from focus (SFF) techniques cannot preserve depth edges and fine structural details from a sequence of multi-focus images. Moreover, noise in the sequence of multi-focus images affects the accuracy of the depth map. In this…

Computer Vision and Pattern Recognition · Computer Science 2022-01-19 Yuwen Li , Zhengguo Li , Chaobing Zheng , Shiqian Wu