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Mild cognitive impairment(MCI) is a precursor of Alzheimer's disease(AD), and the detection of MCI is of great clinical significance. Analyzing the structural brain networks of patients is vital for the recognition of MCI. However, the…
Alzheimer's disease (AD) is a progressive and incurable neurodegenerative disease which destroys brain cells and causes loss to patient's memory. An early detection can prevent the patient from further damage of the brain cells and hence…
Even as deep neural networks (DNNs) have achieved remarkable success on vision-related tasks, their performance is brittle to transformations in the input. Of particular interest are semantic transformations that model changes that have a…
Deep Neural Networks (DNNs) are computationally and memory intensive, which makes their hardware implementation a challenging task especially for resource constrained devices such as IoT nodes. To address this challenge, this paper…
Image denoising is a critical task in various scientific fields such as medical imaging and material characterization, where the accurate recovery of underlying structures from noisy data is essential. Although supervised denoising…
MRI-based brain age estimation models aim to assess a subject's biological brain age based on information, such as neuroanatomical features. Various factors, including neurodegenerative diseases, can accelerate brain aging and measuring…
Adversarial attacks have been shown to be highly effective at degrading the performance of deep neural networks (DNNs). The most prominent defense is adversarial training, a method for learning a robust model. Nevertheless, adversarial…
Multiple different approaches of generating adversarial examples have been proposed to attack deep neural networks. These approaches involve either directly computing gradients with respect to the image pixels, or directly solving an…
Age-Related Macular Degeneration (AMD) is an asymptomatic retinal disease which may result in loss of vision. There is limited access to high-quality relevant retinal images and poor understanding of the features defining sub-classes of…
Recent advances in Generative Adversarial Learning allow for new modalities of image super-resolution by learning low to high resolution mappings. In this paper we present our work using Generative Adversarial Networks (GANs) with…
Affine image registration is a cornerstone of medical image analysis. While classical algorithms can achieve excellent accuracy, they solve a time-consuming optimization for every image pair. Deep-learning (DL) methods learn a function that…
The ability to predict the future trajectory of a patient is a key step toward the development of therapeutics for complex diseases such as Alzheimer's disease (AD). However, most machine learning approaches developed for prediction of…
This paper proposes a set of new error criteria and learning approaches, Adaptive Normalized Risk-Averting Training (ANRAT), to attack the non-convex optimization problem in training deep neural networks (DNNs). Theoretically, we…
Volume change measures derived from longitudinal MRI (e.g. hippocampal atrophy) are a well-studied biomarker of disease progression in Alzheimer's Disease (AD) and are used in clinical trials to track the therapeutic efficacy of…
In recent years, deep generative models, such as Generative Adversarial Network (GAN), has grabbed significant attention in the field of computer vision. This project focuses on the application of GAN in image deblurring with the aim of…
In open data sets of functional magnetic resonance imaging (fMRI), the heterogeneity of the data is typically attributed to a combination of factors, including differences in scanning procedures, the presence of confounding effects, and…
Deep learning techniques have led to state-of-the-art image super resolution with natural images. Normally, pairs of high-resolution and low-resolution images are used to train the deep learning models. These techniques have also been…
Researchers have developed excellent feed-forward models that learn to map images to desired outputs, such as to the images' latent factors, or to other images, using supervised learning. Learning such mappings from unlabelled data, or…
Simulating prospective magnetic resonance imaging (MRI) scans from a given individual brain image is challenging, as it requires accounting for canonical changes in aging and/or disease progression while also considering the individual…
We propose a deep neural network for supervised learning on neuroanatomical shapes. The network directly operates on raw point clouds without the need for mesh processing or the identification of point correspondences, as spatial…