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This work introduces the Burdened Bayesian Logistic Regression Model (BBLRM), an enhancement of the Bayesian Logistic Regression Model (BLRM) for dose-finding in phase I oncology trials. The BLRM determines the maximum tolerated dose (MTD)…

Methodology · Statistics 2025-08-18 Andrea Nizzardo , Luca Genetti , Marco Pergher

Control Barrier Functions (CBFs) provide a powerful framework for ensuring safety in dynamical systems. However, their application typically relies on full state information, which is often violated in real-world due to the availability of…

Systems and Control · Electrical Eng. & Systems 2026-05-19 Vaishnavi Jagabathula , Ahan Basu , Pushpak Jagtap

Sampling-based motion planning methods for manipulators in crowded environments often suffer from expensive collision checking and high sampling complexity, which make them difficult to use in real time. To address this issue, we propose a…

Robotics · Computer Science 2024-04-02 Mingxin Yu , Chenning Yu , M-Mahdi Naddaf-Sh , Devesh Upadhyay , Sicun Gao , Chuchu Fan

RDD (Regression discontinuity design) is a widely used framework for identifying and estimating causal effects at the cutoff of a single running variable. In practice, however, decision-making often involves multiple thresholds and…

The problem of placing or selecting sensors and control nodes plays a pivotal role in the operation of dynamic networks. This paper proposes optimal algorithms and heuristics to solve the simultaneous sensor and actuator selection problem…

Optimization and Control · Mathematics 2019-03-11 Sebastian A. Nugroho , Ahmad F. Taha , Nikolaos Gatsis , Tyler H. Summers , Ram Krishnan

This work presents a new method for online selection of multiple penalty parameters for the alternating direction method of multipliers (ADMM) algorithm applied to optimization problems with multiple constraints or functionals with block…

Image and Video Processing · Electrical Eng. & Systems 2026-04-21 Luke Lozenski , Michael T. McCann , Brendt Wohlberg

This paper proposes a new logic optimization paradigm based on circuit simulation, which reduces the need for Boolean computations such as SAT-solving or constructing BDDs. The paper develops a Boolean resubstitution framework to…

Logic in Computer Science · Computer Science 2020-07-07 Siang-Yun Lee , Heinz Riener , Alan Mishchenko , Robert K. Brayton , Giovanni De Micheli

Background. Designing trials to reduce treatment duration is important in several therapeutic areas, including TB and antibiotics. We recently proposed a new randomised trial design to overcome some of the limitations of standard two-arm…

Minimum Bayes risk (MBR) decoding is a decision rule of text generation, which selects the hypothesis that maximizes the expected utility and robustly generates higher-quality texts than maximum a posteriori (MAP) decoding. However, it…

Computation and Language · Computer Science 2025-09-17 Hiroyuki Deguchi , Masaaki Nagata

The histogram is an analysis tool in widespread use within many sciences, with high energy physics as a prime example. However, there exists an inherent bias in the choice of binning for the histogram, with different choices potentially…

Data Analysis, Statistics and Probability · Physics 2014-05-21 Abram Krislock , Nathan Krislock

We consider the problem of multiple hypothesis testing with generic side information: for each hypothesis $H_i$ we observe both a p-value $p_i$ and some predictor $x_i$ encoding contextual information about the hypothesis. For large-scale…

Methodology · Statistics 2018-07-26 Lihua Lei , William Fithian

When deploying autonomous agents in unstructured environments over sustained periods of time, adaptability and robustness oftentimes outweigh optimality as a primary consideration. In other words, safety and survivability constraints play a…

Systems and Control · Electrical Eng. & Systems 2021-04-08 Motoya Ohnishi , Gennaro Notomista , Masashi Sugiyama , Magnus Egerstedt

We propose a control design method for linear time-invariant systems that iteratively learns to satisfy unknown polyhedral state constraints. At each iteration of a repetitive task, the method constructs an estimate of the unknown…

Systems and Control · Electrical Eng. & Systems 2023-06-13 Monimoy Bujarbaruah , Charlott Vallon , Francesco Borrelli

Time delays in feedback control loops can cause controllers to respond too late, and with excessively large corrective actions, leading to unsafe behavior (violation of state constraints) and controller infeasibility (violation of input…

Systems and Control · Electrical Eng. & Systems 2026-03-26 Adam K. Kiss , Ersin Das , Tamas G. Molnar , Aaron D. Ames

Factor graphs have demonstrated remarkable efficiency for robotic perception tasks, particularly in localization and mapping applications. However, their application to optimal control problems -- especially Model Predictive Control (MPC)…

Robotics · Computer Science 2025-06-18 Anas Abdelkarim , Holger Voos , Daniel Görges

The barrier function method for safety control typically assumes the availability of full state information. Unfortunately, in many scenarios involving uncertain dynamical systems, full state information is often unavailable. In this paper,…

Systems and Control · Electrical Eng. & Systems 2023-08-02 Binghan He , Takashi Tanaka

Bayesian optimal experimental design (OED) seeks to conduct the most informative experiment under budget constraints to update the prior knowledge of a system to its posterior from the experimental data in a Bayesian framework. Such…

Machine Learning · Computer Science 2024-02-29 Rafael Orozco , Felix J. Herrmann , Peng Chen

A binary string of length $2^k$ induces the Boolean function of $k$ variables whose Shannon expansion is the given binary string. This Boolean function then is representable via a unique reduced ordered binary decision diagram (ROBDD). The…

Information Theory · Computer Science 2011-11-08 J. Kieffer , P. Flajolet , E. -h. Yang

Distributed Lag Models (DLMs) and similar regression approaches such as MIDAS have been used for many decades in econometrics and more recently to investigate how poor air quality adversely affects human health. In this paper we describe…

Methodology · Statistics 2025-01-30 Daniel Dempsey , Jason Wyse

Combinatorial interaction testing has been addressed as an effective software testing technique recently. It shows its ability to reduce the number of test cases that have to be considered for software-under-test by taking the combinations…

Software Engineering · Computer Science 2019-05-17 Bestoun S. Ahmed
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