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We propose a novel approach to generate samples from the conditional distribution of patient-specific cardiovascular models given a clinically aquired image volume. A convolutional neural network architecture with dropout layers is first…

Quantitative Methods · Quantitative Biology 2021-09-01 Gabriel Maher , Casey Fleeter , Daniele Schiavazzi , Alison Marsden

Spatiotemporal graph represents a crucial data structure where the nodes and edges are embedded in a geometric space and can evolve dynamically over time. Nowadays, spatiotemporal graph data is becoming increasingly popular and important,…

Machine Learning · Computer Science 2022-03-02 Yuanqi Du , Xiaojie Guo , Hengning Cao , Yanfang Ye , Liang Zhao

High-fidelity computational models of cardiac mechanics provide mechanistic insight into the heart function but are computationally prohibitive for routine clinical use. Surrogate models can accelerate simulations, but generalization across…

Machine Learning · Computer Science 2026-02-25 Davide Carrara , Marc Hirschvogel , Francesca Bonizzoni , Stefano Pagani , Simone Pezzuto , Francesco Regazzoni

Deep learning (DL) methods where interpretability is intrinsically considered as part of the model are required to better understand the relationship of clinical and imaging-based attributes with DL outcomes, thus facilitating their use in…

Image and Video Processing · Electrical Eng. & Systems 2022-12-13 Irem Cetin , Maialen Stephens , Oscar Camara , Miguel Angel Gonzalez Ballester

Personalized cardiac mechanics modeling is a powerful tool for understanding the biomechanics of cardiac function in health and disease and assisting in treatment planning. However, current models are limited to using medical images…

Medical Physics · Physics 2024-04-09 Lei Shi , Ian Chen , Hiroo Takayama , Vijay Vedula

Graph-structured combinatorial problems in complex networks are prevalent in many domains, and are computationally demanding due to their complexity and non-linear nature. Traditional evolutionary algorithms (EAs), while robust, often face…

Neural and Evolutionary Computing · Computer Science 2025-09-16 Jie Zhao , Kang Hao Cheong

The interpretation of the electrocardiogram (ECG) gives clinical information and helps in assessing heart function. There are distinct ECG patterns associated with a specific class of arrythmia. The convolutional neural network is currently…

Signal Processing · Electrical Eng. & Systems 2022-01-31 Zeineb Fki , Boudour Ammar , Mounir Ben Ayed

In end-to-end optimized learned image compression, it is standard practice to use a convolutional variational autoencoder with generalized divisive normalization (GDN) to transform images into a latent space. Recently, Operational Neural…

Image and Video Processing · Electrical Eng. & Systems 2021-05-31 M. Akın Yılmaz , Onur Keleş , Hilal Güven , A. Murat Tekalp , Junaid Malik , Serkan Kıranyaz

As deep Variational Auto-Encoder (VAE) frameworks become more widely used for modeling biomolecular simulation data, we emphasize the capability of the VAE architecture to concurrently maximize the timescale of the latent space while…

Chemical Physics · Physics 2021-12-08 Hannah K. Wayment-Steele , Vijay S. Pande

Density estimation, compression and data generation are crucial tasks in artificial intelligence. Variational Auto-Encoders (VAEs) constitute a single framework to achieve these goals. Here, we present a novel class of generative models,…

Machine Learning · Statistics 2021-07-07 Ioannis Gatopoulos , Jakub M. Tomczak

Generative modeling of 3D brain MRIs presents difficulties in achieving high visual fidelity while ensuring sufficient coverage of the data distribution. In this work, we propose to address this challenge with composable, multiscale…

Image and Video Processing · Electrical Eng. & Systems 2023-01-12 Jaivardhan Kapoor , Jakob H. Macke , Christian F. Baumgartner

Variational autoencdoers (VAE) are a popular approach to generative modelling. However, exploiting the capabilities of VAEs in practice can be difficult. Recent work on regularised and entropic autoencoders have begun to explore the…

Machine Learning · Computer Science 2022-03-02 Gregory A. Daly , Jonathan E. Fieldsend , Gavin Tabor

Graph convolutional neural networks (GCNN) have been successfully applied to many different graph based learning tasks including node and graph classification, matrix completion, and learning of node embeddings. Despite their impressive…

Machine Learning · Computer Science 2019-10-29 Soumyasundar Pal , Florence Regol , Mark Coates

The variational auto-encoder (VAE) is a popular method for learning a generative model and embeddings of the data. Many real datasets are hierarchically structured. However, traditional VAEs map data in a Euclidean latent space which cannot…

Machine Learning · Statistics 2019-11-27 Emile Mathieu , Charline Le Lan , Chris J. Maddison , Ryota Tomioka , Yee Whye Teh

While unsupervised variational autoencoders (VAE) have become a powerful tool in neuroimage analysis, their application to supervised learning is under-explored. We aim to close this gap by proposing a unified probabilistic model for…

Machine Learning · Computer Science 2019-07-15 Qingyu Zhao , Ehsan Adeli , Nicolas Honnorat , Tuo Leng , Kilian M. Pohl

The ability to extract generative parameters from high-dimensional fields of data in an unsupervised manner is a highly desirable yet unrealized goal in computational physics. This work explores the use of variational autoencoders (VAEs)…

Computational Physics · Physics 2021-11-16 Christian Jacobsen , Karthik Duraisamy

In recent years Variation Autoencoders have become one of the most popular unsupervised learning of complicated distributions.Variational Autoencoder (VAE) provides more efficient reconstructive performance over a traditional autoencoder.…

Machine Learning · Statistics 2017-07-12 Gautam Ramachandra

Graph simulation has recently received a surge of attention in graph processing and analytics. In real-life applications, e.g. social science, biology, and chemistry, many graphs are composed of a series of evolving graphs (i.e., temporal…

Machine Learning · Computer Science 2025-10-08 Sheng Xiang , Chenhao Xu , Dawei Cheng , Xiaoyang Wang , Ying Zhang

Extracting meaningful information from high-dimensional data poses a formidable modeling challenge, particularly when the data is obscured by noise or represented through different modalities. This research proposes a novel non-parametric…

Machine Learning · Computer Science 2024-08-27 Navid Ziaei , Behzad Nazari , Uri T. Eden , Alik Widge , Ali Yousefi

Learning low-dimensional representations of single-cell transcriptomics has become instrumental to its downstream analysis. The state of the art is currently represented by neural network models such as variational autoencoders (VAEs) which…

Machine Learning · Computer Science 2024-02-01 Viktoria Schuster , Anders Krogh