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We present multiscale models of cancer tumor invasion with components at the molecular, cellular, and tissue levels. We provide biological justifications for the model components, present computational results from the model, and discuss…

Quantitative Methods · Quantitative Biology 2023-02-14 Bruce P. Ayati , Glenn F. Webb , Alexander R. A. Anderson

In this work, we investigate a fractional-order tumor growth model aimed at capturing memory effects and nonlocal temporal dynamics inherent to tumor evolution. The model is formulated using Caputo fractional derivatives and incorporates…

Medical Physics · Physics 2026-03-17 Karen Escutia , Carlos Islas , Pablo Padilla

This research presents a machine-learning approach for tumor detection in medical images using convolutional neural networks (CNNs). The study focuses on preprocessing techniques to enhance image features relevant to tumor detection,…

Image and Video Processing · Electrical Eng. & Systems 2024-03-01 Ha Anh Vu

We investigate the evolution of tumor growth relying on a nonlinear model of partial differential equations which incorporates mechanical laws for tissue compression combined with rules for nutrients availability and drug application.…

Numerical Analysis · Mathematics 2016-02-23 Konstantina Trivisa , Franziska Weber

Glioblastoma are known to infiltrate the brain parenchyma instead of forming a solid tumor mass with a defined boundary. Only the part of the tumor with high tumor cell density can be localized through imaging directly. In contrast, brain…

In the clinical diagnosis and treatment of brain tumors, manual image reading consumes a lot of energy and time. In recent years, the automatic tumor classification technology based on deep learning has entered people's field of vision.…

Image and Video Processing · Electrical Eng. & Systems 2021-04-07 Yuhao Zhang , Shuhang Wang , Haoxiang Wu , Kejia Hu , Shufan Ji

In this work we present a flexible tool for tumor progression, which simulates the evolutionary dynamics of cancer. Tumor progression implements a multi-type branching process where the key parameters are the fitness landscape, the mutation…

Populations and Evolution · Quantitative Biology 2013-03-22 Johannes G. Reiter , Ivana Bozic , Krishnendu Chatterjee , Martin A. Nowak

Automatic brain tumor segmentation plays an important role for diagnosis, surgical planning and treatment assessment of brain tumors. Deep convolutional neural networks (CNNs) have been widely used for this task. Due to the relatively small…

Computer Vision and Pattern Recognition · Computer Science 2019-02-26 Guotai Wang , Wenqi Li , Sebastien Ourselin , Tom Vercauteren

State-of-the-art brain tumor segmentation is based on deep learning models applied to multi-modal MRIs. Currently, these models are trained on images after a preprocessing stage that involves registration, interpolation, brain extraction…

Image and Video Processing · Electrical Eng. & Systems 2022-12-29 Bruno Machado Pacheco , Guilherme de Souza e Cassia , Danilo Silva

Advances in computing technology have allowed researchers across many fields of endeavor to collect and maintain vast amounts of observational statistical data such as clinical data, biological patient data, data regarding access of web…

Computer Vision and Pattern Recognition · Computer Science 2014-01-24 Narkhede Sachin G , Vaishali Khairnar

During the last decades, medical observations and multiscale data concerning tumor growth are mounting. At the same time, contemporary imaging techniques well established in clinical practice, provide a variety of information on real-time,…

Tissues and Organs · Quantitative Biology 2017-12-11 Markos Antonopoulos , Georgios Stamatakos

The ability to estimate how a tumor might evolve in the future could have tremendous clinical benefits, from improved treatment decisions to better dose distribution in radiation therapy. Recent work has approached the glioma growth…

This study explores the application of deep learning techniques in the automated detection and segmentation of brain tumors from MRI scans. We employ several machine learning models, including basic logistic regression, Convolutional Neural…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Jack Krolik , Jake Lynn , John Henry Rudden , Dmytro Vremenko

We explore encoding brain symmetry into a neural network for a brain tumor segmentation task. A healthy human brain is symmetric at a high level of abstraction, and the high-level asymmetric parts are more likely to be tumor regions. Paying…

Computer Vision and Pattern Recognition · Computer Science 2017-11-20 Hejia Zhang , Xia Zhu , Theodore L. Willke

In this paper, we conduct a thorough mathematical analysis of a tumor growth model with treatments. The model is a system describing the evolution of metastatic tumors and the number of cells present in a primary tumor. The former evolution…

Analysis of PDEs · Mathematics 2022-05-25 Slah Eddin Ben Abdeljalil , Atef Ben Essid , Saloua Mani Aouadi

The brain tumor is the most aggressive kind of tumor and can cause low life expectancy if diagnosed at the later stages. Manual identification of brain tumors is tedious and prone to errors. Misdiagnosis can lead to false treatment and thus…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Dmytro Filatov , Ghulam Nabi Ahmad Hassan Yar

Accurate tumor classification is essential for selecting effective treatments, but current methods have limitations. Standard tumor grading, which categorizes tumors based on cell differentiation, is not recommended as a stand-alone…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Marianne Abémgnigni Njifon , Tobias Weber , Viktor Bezborodov , Tyll Krueger , Dominic Schuhmacher

Five different threshold segmentation based approaches have been reviewed and compared over here to extract the tumor from set of brain images. This research focuses on the analysis of image segmentation methods, a comparison of five…

Computer Vision and Pattern Recognition · Computer Science 2015-03-10 Muhammad Ali Qadar , Yan Zhaowen

One of the most important tasks in medical image processing is the brain's whole tumor segmentation. It assists in quicker clinical assessment and early detection of brain tumors, which is crucial for lifesaving treatment procedures of…

Computer Vision and Pattern Recognition · Computer Science 2020-09-15 Apurva Pandya , Catherine Samuel , Nisargkumar Patel , Vaibhavkumar Patel , Thangarajah Akilan

In this paper, we present a fully automatic brain tumor segmentation and classification model using a Deep Convolutional Neural Network that includes a multiscale approach. One of the differences of our proposal with respect to previous…

Image and Video Processing · Electrical Eng. & Systems 2024-02-12 Francisco Javier Díaz-Pernas , Mario Martínez-Zarzuela , Míriam Antón-Rodríguez , David González-Ortega