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Early estimates of the transmission potential of emerging and re-emerging infections are increasingly used to inform public health authorities on the level of risk posed by outbreaks. Existing methods to estimate the reproduction number…

Quantitative Methods · Quantitative Biology 2016-10-10 Gerardo Chowell , Cécile Viboud , Lone Simonsen , Seyed Moghadas

We present a novel model that describes the within-host evolutionary dynamics of parasites undergoing antigenic variation. The approach uses a multi-type branching process with two types of entities defined according to their relationship…

Populations and Evolution · Quantitative Biology 2013-11-18 Gustavo Guerberoff , Fernando Alvarez-Valin

During infectious disease epidemics, pathogen transmission occurs in host populations made up of interacting subpopulations. Using stochastic simulation and analytical approximations, we examine how outbreak sizes in networked populations…

Populations and Evolution · Quantitative Biology 2026-01-21 Makoto Ueki , Robin N. Thompson , Murad Banaji

Understanding dynamics of an infectious disease helps in designing appropriate strategies for containing its spread in a population. Recent mathematical models are aimed at studying dynamics of some specific types of infectious diseases. In…

Dynamical Systems · Mathematics 2015-02-05 P. Raja Sekhara Rao , M. Naresh Kumar

Mathematical disease modelling has long operated under the assumption that any one infectious disease is caused by one transmissible pathogen spreading among a population. This paradigm has been useful in simplifying the biological reality…

Populations and Evolution · Quantitative Biology 2021-06-02 Blake J. M. Williams , Guillaume St-Onge , Laurent Hébert-Dufresne

We formulate a compartmental model for the propagation of a respiratory disease in a patchy environment. The patches are connected through the mobility of individuals, and we assume that disease transmission and recovery are possible during…

Populations and Evolution · Quantitative Biology 2021-10-11 Indrajit Ghosh , Sk Shahid Nadim , Soumyendu Raha , Debnath Pal

We introduce a generalized version of the frog model to describe the invasion of a parasite population in a spatially structured immobile host population with host immunity on the integer line. Parasites move according to simple symmetric…

Probability · Mathematics 2025-02-17 Sascha Franck , Cornelia Pokalyuk

We are interested in modeling some two-level population dynamics, resulting from the interplay of ecological interactions and phenotypic variation of individuals (or hosts) and the evolution of cells (or parasites) of two types living in…

Probability · Mathematics 2011-01-21 Sylvie Méléard , Sylvie Roelly

Most previous studies of epidemic dynamics on complex networks suppose that the disease will eventually stabilize at either a disease-free state or an endemic one. In reality, however, some epidemics always exhibit sporadic and recurrent…

Physics and Society · Physics 2013-11-19 Xiao-Long Peng , Michael Small , Xin-Jian Xu , Xinchu Fu

In this work we develop a discrete model of competing species affected by a common parasite. We analyze the influence of the fast development of the shared disease on the community dynamics. The model is presented under the form of a two…

Dynamical Systems · Mathematics 2024-02-07 Rafael Bravo de La Parra , Luis Sanz

Mathematical modeling of disease outbreaks can infer the future trajectory of an epidemic, which can inform policy decisions. Another task is inferring the origin of a disease, which is relatively difficult with current mathematical models.…

Physics and Society · Physics 2022-08-31 Mehrad Ansari , David Soriano-Paños , Gourab Ghoshal , Andrew D. White

We study a mosquito-borne epidemic model where the vector population is distinct in aquatic and adult stages and a saturating effect of disease transmission is assumed to ocurr when the number of infectious (humans and mosquitoes) becomes…

Populations and Evolution · Quantitative Biology 2014-02-10 E. Avila-Vales , B. Buonomo , N. Chan-Chi

Interactions among multiple infectious agents are increasingly recognized as a fundamental issue in the understanding of key questions in public health, regarding pathogen emergence, maintenance, and evolution. The full description of…

Populations and Evolution · Quantitative Biology 2013-08-21 Chiara Poletto , Sandro Meloni , Vittoria Colizza , Yamir Moreno , Alessandro Vespignani

Insect-borne diseases are diseases carried by insects affecting humans, animals or plants. They have the potential to generate massive outbreaks such as the Zika epidemic in 2015-2016 mostly distributed in the Americas, the Pacific and…

Analysis of PDEs · Mathematics 2020-02-19 Olivier Martin , Yasmil Fernandez-Diclo , Jerome Coville , Samuel Soubeyrand

We investigate a model for spatial epidemics explicitly taking into account bi-directional movements between base and destination locations on individual mobility networks. We provide a systematic analysis of generic dynamical features of…

Physics and Society · Physics 2012-03-07 Vitaly Belik , Theo Geisel , Dirk Brockmann

This paper introduces a new optimal control model to describe and control the dynamics of infectious diseases. In the present model, the average time of isolation (i.e. hospitalization) of infectious population is the main time-dependent…

Optimization and Control · Mathematics 2015-05-06 Robin J. Evans , Musa Mammadov

Tuberculosis (TB) remains a formidable global health challenge, driven by complex spatiotemporal transmission dynamics and influenced by factors such as population mobility and behavioral changes. We propose an Epidemic-Guided Deep Learning…

Machine Learning · Computer Science 2025-10-29 Madhab Barman , Madhurima Panja , Nachiketa Mishra , Tanujit Chakraborty

Mathematical modelling of epidemiological and coevolutionary dynamics is widely being used to improve disease management strategies of infectious diseases. Many diseases present some form of intra-host quiescent stage, also known as covert…

Populations and Evolution · Quantitative Biology 2022-05-26 Usman Sanusi , Sona John , Johannes Mueller , Aurélien Tellier

Transmission dynamics of infectious diseases are often studied using compartmental mathematical models, which are commonly represented as systems of autonomous ordinary differential equations. A key step in the analysis of such models is to…

Populations and Evolution · Quantitative Biology 2025-12-15 David J. D. Earn , C. Connell McCluskey

Stochasticity and spatial heterogeneity are of great interest recently in studying the spread of an infectious disease. The presented method solves an inverse problem to discover the effectively decisive topology of a heterogeneous network…

Artificial Intelligence · Computer Science 2015-03-13 Yoshiharu Maeno