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Recent progress on molecular theories of hydration of nonpolar solutes in aqueous solution has led to new ways of thinking about the old issue of free, or "available," volume in liquids. This article surveys the principal new results with…

Chemical Physics · Physics 2007-05-23 Lawrence R. Pratt , Shekhar Garde , Gerhard Hummer

The hydrophobic interaction, often combined with the hydrophilic or ionic interactions, makes the behavior of aqueous solutions very rich and plays an important role in biological systems. Theoretical and computer simulation studies haven…

Soft Condensed Matter · Physics 2024-11-05 Hidefumi Naito , Tomonari Sumi , Kenichiro Koga

The strength of hydrogen bonding in water is stronger than that of van der waals interaction, therefore water may play an important role in the process of hydrophobic effects. When a hydrophobic solute is dissolved into water, an interface…

Chemical Physics · Physics 2017-03-08 Qiang Sun

The thermodynamics of hydration changes gradually from entropic for small solutes to enthalpic for large ones. The small-to-large crossover lengthscale of hydrophobic hydration depends on the thermodynamic conditions of the solvent such as…

Soft Condensed Matter · Physics 2015-06-15 Yuri S. Djikaev , Eli Ruckenstein

We investigate the curvature-dependence of water dynamics in the vicinity of hydrophobic spherical solutes using molecular dynamics simulations. For both, the lateral and perpendicular diffusivity as well as for H-bond kinetics of water in…

Soft Condensed Matter · Physics 2016-01-22 R. Gregor Weiß , Matthias Heyden , Joachim Dzubiella

Interfaces are a most common motif in complex systems. To understand how the presence of interfaces affect hydrophobic phenomena, we use molecular simulations and theory to study hydration of solutes at interfaces. The solutes range in size…

Soft Condensed Matter · Physics 2014-09-05 Amish J. Patel , Patrick Varilly , Sumanth N. Jamadagni , Hari Acharya , Shekhar Garde , David Chandler

Based on our recent study on physical origin of hydrophobic effects, this is applied to investigate the dependence of hydrophobic interactions on the solute size. As two same hydrophobic solutes are dissolved into water, the hydration free…

Soft Condensed Matter · Physics 2018-03-07 Qiang Sun

Hydrophobic hydration at metal/water interfaces actively contributes to the energetics of electrochemical reactions, e.g. CO$_2$ and N$_2$ reduction, where small hydrophobic molecules are involved. In this work, constant applied potential…

Chemical Physics · Physics 2021-09-03 Alessandra Serva , Mathieu Salanne , Martina Havenith , Simone Pezzotti

The hydration free energies of ions exhibit an approximately quadratic dependence on the ionic charge, as predicted by the Born model. We analyze this behavior using second-order perturbation theory. This provides effective methods to…

chem-ph · Physics 2008-02-03 Gerhard Hummer , Lawrence R. Pratt , Angel E. Garcia

We present a probabilistic approach to water-water hydrogen bonding that allows one to obtain an analytic expression for the number of bonds per water molecule as a function of both its distance to a hydrophobic particle and hydrophobe…

Soft Condensed Matter · Physics 2013-03-20 Yuri S. Djikaev , Eli Ruckenstein

The hydration free energy of a macromolecule is the central property of interest for understanding its distribution over conformations and its state of aggregation. Calculating the hydration free energy of a macromolecule in all-atom…

Soft Condensed Matter · Physics 2022-06-22 Rohan S. Adhikari , Arjun Valiya Parambathu , Walter G. Chapman , Dilipkumar N. Asthagiri

A theoretical model for the effect of water hydrogen bonding on the thermodynamics of hydrophobic hydration is proposed as a combination of the classical density functional theory with the recently developed probabilistic approach to water…

Statistical Mechanics · Physics 2011-06-16 Yuri S. Djikaev

We consider the theoretical description of a fluid adsorbed in a nanopore. Hysteresis and discontinuities in the isotherms in general hampers the determination of equilibrium thermodynamic properties, even in computer simulations. A…

Soft Condensed Matter · Physics 2015-06-18 Joël Puibasset , Edouard Kierlik , Gilles Tarjus

Biological cells use droplets to separate components and spatially control their interior. Experiments demonstrate that the complex, crowded cellular environment affects the droplet arrangement and their sizes. To understand this behavior,…

Soft Condensed Matter · Physics 2021-10-27 Estefania Vidal-Henriquez , David Zwicker

Water shapes and defines the properties of biological systems. Therefore, understanding the nature of the mutual interaction between water and biological systems is of primary importance for a proper assessment of biological activity and…

Soft Condensed Matter · Physics 2021-01-18 Fausto Martelli , Carles Calero , Giancarlo Fanzese

By using large-scale molecular dynamics simulations, the dynamics of two-dimensional (2D) supercooled liquids turns out to be dependent on the system size, while the size dependence is not pronounced in three dimensional (3D) systems. It is…

Statistical Mechanics · Physics 2016-12-07 Hayato Shiba , Yasunori Yamada , Takeshi Kawasaki , Kang Kim

Solvent plays an important role in the relative motion of nanoscopic bodies, and the study of such phenomena can help elucidate the mechanism of hydrophobic assembly, as well as the influence of solvent-mediated effects on in vivo motion in…

Statistical Mechanics · Physics 2011-12-12 Joseph A. Morrone , Jingyuan Li , B. J. Berne

In recent experiments, small, thick-walled vesicles with a narrow size distribution were formed from copolymers where the degree of polymerisation of the hydrophobic block, N_B, was significantly greater than that of the hydrophilic block,…

Soft Condensed Matter · Physics 2017-09-12 M. J. Greenall

We study an autocatalytic system consisting of several interacting chemical species. We observe a strong dependence of the concentrations of the chemicals on the size of the system. This dependence is caused by the discrete nature of the…

Biological Physics · Physics 2007-05-23 Yuichi Togashi , Kunihiko Kaneko

The thermodynamics for a system with given temperature, density, and volume is described by the Canonical ensemble. The thermodynamics for a corresponding system with the same temperature, volume, and average density is described by the…

Statistical Mechanics · Physics 2016-01-12 Debajit Chakraborty , James Dufty , Valentin V. Karasiev
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