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Data-driven cell tracking and segmentation methods in biomedical imaging require diverse and information-rich training data. In cases where the number of training samples is limited, synthetic computer-generated data sets can be used to…

Computer Vision and Pattern Recognition · Computer Science 2023-10-16 David Wiesner , Julian Suk , Sven Dummer , Tereza Nečasová , Vladimír Ulman , David Svoboda , Jelmer M. Wolterink

Deep learning-based 3-dimensional (3D) shape reconstruction from 2-dimensional (2D) magnetic resonance imaging (MRI) has become increasingly important in medical disease diagnosis, treatment planning, and computational modeling. This review…

Machine Learning · Computer Science 2025-10-03 Emma McMillian , Abhirup Banerjee , Alfonso Bueno-Orovio

Predicting the future development of an anatomical shape from a single baseline observation is a challenging task. But it can be essential for clinical decision-making. Research has shown that it should be tackled in curved shape spaces, as…

Computer Vision and Pattern Recognition · Computer Science 2024-02-23 Doğa Türkseven , Islem Rekik , Christoph von Tycowicz , Martin Hanik

Recent advances in deep learning have significantly transformed the field of 3D shape generation, enabling the synthesis of complex, diverse, and semantically meaningful 3D objects. This survey provides a comprehensive overview of the…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Nicolas Caytuiro , Ivan Sipiran

In real-world clinical practice, overlooking unanticipated findings can result in serious consequences. However, supervised learning, which is the foundation for the current success of deep learning, only encourages models to identify…

The emergence of explainability methods has enabled a better comprehension of how deep neural networks operate through concepts that are easily understood and implemented by the end user. While most explainability methods have been designed…

Neurons and Cognition · Quantitative Biology 2022-03-17 Fernanda L. Ribeiro , Steffen Bollmann , Ross Cunnington , Alexander M. Puckett

Alzheimer disease (AD) diagnosis and prognosis increasingly rely on machine learning (ML) models. Although these models provide good results, clinical adoption is limited by the need for technical expertise and the lack of trustworthy and…

Machine Learning · Computer Science 2026-03-11 Pablo Guillén , Enrique Frias-Martinez

The emergence of deep learning networks raises a need for explainable AI so that users and domain experts can be confident applying them to high-risk decisions. In this paper, we leverage data from the latent space induced by deep learning…

Machine Learning · Computer Science 2019-09-10 Alan H. Gee , Diego Garcia-Olano , Joydeep Ghosh , David Paydarfar

Medical image classification is one of the most critical problems in the image recognition area. One of the major challenges in this field is the scarcity of labelled training data. Additionally, there is often class imbalance in datasets…

Image and Video Processing · Electrical Eng. & Systems 2022-09-29 Khushboo Mehra , Hassan Soliman , Soumya Ranjan Sahoo

While objects from different categories can be reliably decoded from fMRI brain response patterns, it has proved more difficult to distinguish visually similar inputs, such as different instances of the same category. Here, we apply a…

Human-Computer Interaction · Computer Science 2021-02-23 Rufin VanRullen , Leila Reddy

Accurate segmentation of tissue in histopathological images can be very beneficial for defining regions of interest (ROI) for streamline of diagnostic and prognostic tasks. Still, adapting to different domains is essential for…

Image and Video Processing · Electrical Eng. & Systems 2023-03-10 Saul Fuster , Farbod Khoraminia , Trygve Eftestøl , Tahlita C. M. Zuiverloon , Kjersti Engan

Pulmonary diseases rank prominently among the principal causes of death worldwide. Curing them will require, among other things, a better understanding of the complex 3D tree-shaped structures within the pulmonary system, such as airways,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-21 Kangxian Xie , Jiancheng Yang , Donglai Wei , Ziqiao Weng , Pascal Fua

The proliferation of high-dimensional datasets in fields such as genomics, healthcare, and finance has created an urgent need for machine learning models that are both highly accurate and inherently interpretable. While traditional deep…

Machine Learning · Computer Science 2025-10-28 Rekha R Nair , Tina Babu , Alavikunhu Panthakkan , Hussain Al-Ahmad , Balamurugan Balusamy

Previous approaches to generate shapes in a 3D setting train a GAN on the latent space of an autoencoder (AE). Even though this produces convincing results, it has two major shortcomings. As the GAN is limited to reproduce the dataset the…

Computer Vision and Pattern Recognition · Computer Science 2021-07-23 Moritz Ibing , Isaak Lim , Leif Kobbelt

Despite the impact of psychiatric disorders on clinical health, early-stage diagnosis remains a challenge. Machine learning studies have shown that classifiers tend to be overly narrow in the diagnosis prediction task. The overlap between…

Current deep learning based detection models tackle detection and segmentation tasks by casting them to pixel or patch-wise classification. To automate the initial mass lesion detection and segmentation on the whole mammographic images and…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Azam Hamidinekoo , Erika Denton , Reyer Zwiggelaar

We develop three efficient approaches for generating visual explanations from 3D convolutional neural networks (3D-CNNs) for Alzheimer's disease classification. One approach conducts sensitivity analysis on hierarchical 3D image…

Computer Vision and Pattern Recognition · Computer Science 2018-07-09 Chengliang Yang , Anand Rangarajan , Sanjay Ranka

Explainable AI aims to render model behavior understandable by humans, which can be seen as an intermediate step in extracting causal relations from correlative patterns. Due to the high risk of possible fatal decisions in image-based…

Computer Vision and Pattern Recognition · Computer Science 2023-06-16 Lukas Klein , João B. S. Carvalho , Mennatallah El-Assady , Paolo Penna , Joachim M. Buhmann , Paul F. Jaeger

While imaging-genetics holds great promise for unraveling the complex interplay between brain structure and genetic variation in neurological disorders, traditional methods are limited to simplistic linear models or to black-box techniques…

Recent successes of Deep Neural Networks (DNNs) in a variety of research tasks, however, heavily rely on the large amounts of labeled samples. This may require considerable annotation cost in real-world applications. Fortunately, active…

Machine Learning · Computer Science 2020-09-08 Qiang Liu , Zhaocheng Liu , Xiaofang Zhu , Yeliang Xiu
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