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The condition of the Glomeruli, or filter sacks, in renal Direct Immunofluorescence (DIF) specimens is a critical indicator for diagnosing kidney diseases. A digital pathology system which digitizes a glass histology slide into a Whole…

Wireless Capsule Endoscopy is one of the most advanced non-invasive methods for the examination of gastrointestinal tracts. An intelligent computer-aided diagnostic system for detecting gastrointestinal abnormalities like polyp, bleeding,…

Convolutional neural networks (CNNs) are a standard tool for computer vision tasks such as image classification. However, typical model architectures may result in the loss of topological information. In specific domains such as…

In recent years, the incidence of vision-threatening eye diseases has risen dramatically, necessitating scalable and accurate screening solutions. This paper presents a comprehensive study on deep learning architectures for the automated…

Hepatocellular carcinoma (HCC) is a common type of liver cancer whose early-stage diagnosis is a common challenge, mainly due to the manual assessment of hematoxylin and eosin-stained whole slide images, which is a time-consuming process…

Accurate diagnostics of a skin lesion is a critical task in classification dermoscopic images. In this research, we form a new type of image features, called hybrid features, which has stronger discrimination ability than single method…

The performance of machine learning algorithms, when used for segmenting 3D biomedical images, does not reach the level expected based on results achieved with 2D photos. This may be explained by the comparative lack of high-volume,…

Fine-grained classification of cervical cells into different abnormality levels is of great clinical importance but remains very challenging. Contrary to traditional classification methods that rely on hand-crafted or engineered features,…

Computer Tomography (CT) images have become quite important to diagnose diseases. CT scan slice contains a vast amount of data that may not be properly examined with the requisite precision and speed using normal visual inspection. A…

Glaucoma is an irreversible ocular disease and is the second leading cause of visual disability worldwide. Slow vision loss and the asymptomatic nature of the disease make its diagnosis challenging. Early detection is crucial for preventing…

Segmentation of white matter lesions and deep grey matter structures is an important task in the quantification of magnetic resonance imaging in multiple sclerosis. In this paper we explore segmentation solutions based on convolutional…

Endoscopy plays a major role in identifying any underlying abnormalities within the gastrointestinal (GI) tract. There are multiple GI tract diseases that are life-threatening, such as precancerous lesions and other intestinal cancers. In…

While deep learning methods are increasingly being applied to tasks such as computer-aided diagnosis, these models are difficult to interpret, do not incorporate prior domain knowledge, and are often considered as a "black-box." The lack of…

Breast cancer is a relatively common cancer among gynecological cancers. Its diagnosis often relies on the pathology of cells in the lesion. The pathological diagnosis of breast cancer not only requires professionals and time, but also…

Breast cancer is one of the main causes of cancer death worldwide. Early diagnostics significantly increases the chances of correct treatment and survival, but this process is tedious and often leads to a disagreement between pathologists.…

Several Deep Learning (DL) methods have recently been proposed for an automated identification of kidney stones during an ureteroscopy to enable rapid therapeutic decisions. Even if these DL approaches led to promising results, they are…

We explore the problem of classification within a medical image data-set based on a feature vector extracted from the deepest layer of pre-trained Convolution Neural Networks. We have used feature vectors from several pre-trained…

Deep learning, as a promising new area of machine learning, has attracted a rapidly increasing attention in the field of medical imaging. Compared to the conventional machine learning methods, deep learning requires no hand-tuned feature…

There has been a long pursuit for precise and reproducible glomerular quantification on renal pathology to leverage both research and practice. When digitizing the biopsy tissue samples using whole slide imaging (WSI), a set of serial…

A kidney transplant can improve the life expectancy and quality of life of patients with end-stage renal failure. Even more patients could be helped with a transplant if the rate of kidneys that are discarded and not transplanted could be…