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Quantitative tissue information, like the light scattering properties, is considered as a key player in the detection of cancerous cells in medical diagnosis. A promising method to obtain these data is optical coherence tomography (OCT). In…

Numerical Analysis · Mathematics 2023-06-21 Leopold Veselka , Peter Elbau , Leonidas Mindrinos , Lisa Krainz , Wolfgang Drexler

In this work we consider the inverse problem of reconstructing the optical properties of a layered medium from an elastography measurement where optical coherence tomography is used as the imaging method. We hereby model the sample as a…

Numerical Analysis · Mathematics 2024-02-23 Peter Elbau , Leonidas Mindrinos , Leopold Veselka

In this work, an inverse problem in the fractional diffusion equation with random source is considered. The measurements used are the statistical moments of the realizations of single point data $u(x_0,t,\omega).$ We build the…

Analysis of PDEs · Mathematics 2020-04-09 Shubin Fu , Zhidong Zhang

In this chapter a general mathematical model of Optical Coherence Tomography (OCT) is presented on the basis of the electromagnetic theory. OCT produces high resolution images of the inner structure of biological tissues. Images are…

Numerical Analysis · Mathematics 2016-04-19 Peter Elbau , Leonidas Mindrinos , Otmar Scherzer

We propose a multiscale approach for a nonlinear Helmholtz problem with possible oscillations in the Kerr coefficient, the refractive index, and the diffusion coefficient. The method does not rely on structural assumptions on the…

Numerical Analysis · Mathematics 2021-12-10 Roland Maier , Barbara Verfürth

In this work, we investigate an inverse problem of recovering multiple orders in a time-fractional diffusion model from the data observed at one single point on the boundary. We prove the unique recovery of the orders together with their…

Numerical Analysis · Mathematics 2021-11-17 Bangti Jin , Yavar Kian

We consider the inverse scattering problem of retrieving the structural parameters of a stratified medium consisting of dispersive materials, given knowledge of the complex reflection coefficient in a finite frequency range. It is shown…

Optics · Physics 2012-08-23 Johannes Skaar , Magnus W. Haakestad

This paper explores the reconstruction of a space-dependent parameter in inverse diffusion problems, proposing a shape-optimization-based approach. We consider a Robin boundary condition, physically motivated in diffuse optical tomography…

Numerical Analysis · Mathematics 2026-01-27 Manabu Machida , Hirofumi Notsu , Julius Fergy Tiongson Rabago

In the paper, we discuss the reconstruction of scalar parameters in a linear diffusion equation with fractional in time differential operators and with additional nonlocal (convolution) terms, which incorporate memory effects in models.…

Analysis of PDEs · Mathematics 2026-03-30 Sergii V. Siryk , Lidiia Tereshchenko , Nataliya Vasylyeva

In this paper we provide a mathematical model for imaging an anisotropic, orthotropic medium with Polarization-Sensitive Optical Coherence Tomography (PS-OCT). The imaging problem is formulated as an inverse scattering problem in three…

Analysis of PDEs · Mathematics 2018-10-22 Peter Elbau , Leonidas Mindrinos , Otmar Scherzer

Optical coherence tomography (OCT) is a widely used imaging technique in the micrometer regime, which gained accelerating interest in medical imaging in the last twenty years. In up-to-date OCT literature [5,6] certain simplifying…

Medical Physics · Physics 2024-02-23 Leopold Veselka , Lisa Krainz , Leonidas Mindrinos , Wolfgang Drexler , Peter Elbau

In the paper, we propose an analytical and numerical approach to identify scalar parameters (coefficients, orders of fractional derivatives) in the multi-term fractional differential operator in time, $\mathbf{D}_t$. To this end, we analyze…

Analysis of PDEs · Mathematics 2026-04-07 Andrii Hulianytskyi , Sergei Pereverzyev , Sergii Siryk , Nataliya Vasylyeva

This paper concerns the reconstruction of multiple elastic parameters (Lam\'e parameters and density) of an inhomogeneous medium embedded in an infinite homogeneous isotropic background in $\mathbb{R}^2$. The direct scattering problem is…

Numerical Analysis · Mathematics 2019-02-13 Gang Bao , Tao Yin , Fang Zeng

We consider the two dimensional quantitative imaging problem of recovering a radiative source inside an absorbing and scattering medium from knowledge of the outgoing radiation measured at the boundary. The medium has an anisotropic…

Numerical Analysis · Mathematics 2021-01-21 Hiroshi Fujiwara , Kamran Sadiq , Alexandru Tamasan

The aim of this paper is to discuss potential advances in PET kinetic models and direct reconstruction of kinetic parameters. As a prominent example we focus on a typical task in perfusion imaging and derive a system of…

Optimization and Control · Mathematics 2014-11-20 Louise Reips , Martin Burger , Ralf Engbers

Inverse scattering in optical coherence tomography (OCT) seeks to recover both structural images and intrinsic tissue optical properties, including refractive index, scattering coefficient, and anisotropy. This inverse problem is…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Jinglun Yu , Yaning Wang , Wenhan Guo , Yuan Gao , Yu Sun , Jin U. Kang

The article deals with a classical inverse problem: the computation of the refractive index of a medium from ultrasound time-of-flight (TOF) measurements. This problem is very popular in seismics but also for tomographic problems in…

Numerical Analysis · Mathematics 2016-08-03 Udo Schroeder , Thomas Schuster

In this paper, we study the mathematical imaging problem of optical diffraction tomography (ODT) for the scenario of a microscopic rigid particle rotating in a trap created, for instance, by acoustic or optical forces. Under the influence…

We consider the imaging problem of the reconstruction of a three-dimensional object via optical diffraction tomography under the assumptions of the Born approximation. Our focus lies in the situation that a rigid object performs an…

Numerical Analysis · Mathematics 2024-07-11 Robert Beinert , Michael Quellmalz

Optical coherence tomography (OCT) captures cross-sectional data and is used for the screening, monitoring, and treatment planning of retinal diseases. Technological developments to increase the speed of acquisition often results in systems…

Image and Video Processing · Electrical Eng. & Systems 2023-01-03 Timothy T. Yu , Da Ma , Jayden Cole , Myeong Jin Ju , Mirza F. Beg , Marinko V. Sarunic
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