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Molecular knowledge resides within three different modalities of information sources: molecular structures, biomedical documents, and knowledge bases. Effective incorporation of molecular knowledge from these modalities holds paramount…

Biomolecules · Quantitative Biology 2023-07-24 Yizhen Luo , Kai Yang , Massimo Hong , Xing Yi Liu , Zaiqing Nie

Quantum Monte Carlo is an efficient technique for finding the ground-state energy and related properties of small molecules. A major challenge remains in accurate determination of a molecule's geometry, i.e. the optimal location of its…

Computational Physics · Physics 2017-04-12 Jan Vrbik

In this paper, we address the challenge of obtaining a comprehensive and symmetric representation of point particle groups, such as atoms in a molecule, which is crucial in physics and theoretical chemistry. The problem has become even more…

Chemical Physics · Physics 2024-02-13 Jigyasa Nigam , Sergey N. Pozdnyakov , Kevin K. Huguenin-Dumittan , Michele Ceriotti

Interactions govern the flow of information and the formation of correlations in quantum systems, dictating the phases of matter found in nature and the forms of entanglement generated in the laboratory. Typical interactions decay with…

This library (collection of subroutines) is presented for calculating standard quantities in the decomposition of many-electron matrix elements in atomic structure theory. These quantities include the coefficients of fractional parentage,…

Atomic Physics · Physics 2007-05-23 G. Gaigalas

Knowledge in materials science is widely dispersed across extensive scientific literature, posing significant challenges to the efficient discovery and integration of new materials. Traditional methods, often reliant on costly and…

Computation and Language · Computer Science 2025-05-16 Yanpeng Ye , Jie Ren , Shaozhou Wang , Yuwei Wan , Imran Razzak , Bram Hoex , Haofen Wang , Tong Xie , Wenjie Zhang

PACKMOL is a widely utilized molecular modeling tool within the computational chemistry community. However, its perceivable advantages have been impeded by the long-standing lack of a robust open-source graphical user interface (GUI) that…

Chemical Physics · Physics 2024-08-26 Jian Huang , Chenchen Wu , Xiner Yang , Zaixing Yang , Shengtang Liu , Gang Yu

Real-space refinement of atomic models in macromolecular crystallography or in cryo electron microscopy fits a model to a map obtained experimentally. This requires generating model maps of a limited resolution which moreover may vary from…

Computational Engineering, Finance, and Science · Computer Science 2022-06-22 Ludmila Urzhumtseva , Vladimir Y. Lunin , Alexandre Urzhumtsev

Genetic algorithms, as implemented in optimal control strategies, are currently successfully exploited in a wide range of problems in molecular physics. In this context, laser control of molecular alignment and orientation remains a very…

Chemical Physics · Physics 2007-05-23 O. Atabek , C. M. Dion

Geometrical Volume-of-Fluid (VoF) methods mainly support structured meshes, and only a small number of contributions in the scientific literature report results with unstructured meshes and three spatial dimensions. Unstructured meshes are…

Computational Physics · Physics 2024-02-07 Tomislav Maric , Douglas B. Kothe , Dieter Bothe

Graphs are central to the chemical sciences, providing a natural language to describe molecules, proteins, reactions, and industrial processes. They capture interactions and structures that underpin materials, biology, and medicine. This…

The computational prediction of atomistic structure is a long-standing problem in physics, chemistry, materials, and biology. Within conventional force-field or {\em ab initio} calculations, structure is determined through energy…

Chemical Physics · Physics 2021-09-15 Dominik Lemm , Guido Falk von Rudorff , O. Anatole von Lilienfeld

Contemporary graph learning algorithms are not well-defined for large molecules since they do not consider the hierarchical interactions among the atoms, which are essential to determine the molecular properties of macromolecules. In this…

Machine Learning · Computer Science 2023-08-02 Nhat Khang Ngo , Truong Son Hy , Risi Kondor

Many fundamental questions in theoretical computer science are naturally expressed as special cases of the following problem: Let $G$ be a complex reductive group, let $V$ be a $G$-module, and let $v,w$ be elements of $V$. Determine if $w$…

Algebraic Geometry · Mathematics 2021-08-16 J. M. Landsberg

We describe a method for modeling the geometry of porous materials. The approach enables the independent selection of crucial parameters, including porosity, pore size distribution, pore shape, and connectivity. Consequently, it can…

Materials Science · Physics 2024-04-19 Felix Buchele , Patric Müller , Michael Blank , Thorsten Pöschel

Formal methods for verification of programs are extended to testing of programs. Their combination is intended to lead to benefits in reliable program development, testing, and evolution. Our geometric theory of testing is intended to serve…

Software Engineering · Computer Science 2022-06-07 Bernhard Moller , Tony Hoare , Zhe Hou , Jin Song Dong

Recent advances in spatial omics technologies have revolutionized our ability to study biological systems with unprecedented resolution. By preserving the spatial context of molecular measurements, these methods enable comprehensive mapping…

Quantitative Methods · Quantitative Biology 2025-09-18 Zhiwei Fan , Tiangang Wang , Kexin Huang , Binwu Ying , Xiaobo Zhou

Computer-aided molecular design (CAMD) studies quantitative structure-property relationships and discovers desired molecules using optimization algorithms. With the emergence of machine learning models, CAMD score functions may be replaced…

Computational Engineering, Finance, and Science · Computer Science 2023-12-07 Shiqiang Zhang , Juan S. Campos , Christian Feldmann , Frederik Sandfort , Miriam Mathea , Ruth Misener

Multimodal normal incestual systems are investigated in terms of multiple categories. The different sorted composition of operators are exhibited as 2-cells in multiple categories built up from 2-categories giving rise to different axioms.…

Category Theory · Mathematics 2015-08-11 Joaquín Díaz Boils

In the first work of this series [physics/0204035] it was shown that the conformational space of a molecule could be described to a fair degree of accuracy by means of a central hyperplane arrangement. The hyperplanes divide the espace into…

Computational Physics · Physics 2008-12-13 Jacques Gabarro-Arpa