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It is a challenging task to accurately perform semantic segmentation due to the complexity of real picture scenes. Many semantic segmentation methods based on traditional deep learning insufficiently captured the semantic and appearance…

Computer Vision and Pattern Recognition · Computer Science 2024-03-13 Haitong Tang , Shuang He , Mengduo Yang , Xia Lu , Qin Yu , Kaiyue Liu , Hongjie Yan , Nizhuan Wang

Proteins are the major building blocks of life, and actuators of almost all chemical and biophysical events in living organisms. Their native structures in turn enable their biological functions which have a fundamental role in drug design.…

In Proteomics, only the de novo peptide sequencing approach allows a partial amino acid sequence of a peptide to be found from a MS/MS spectrum. In this article a preliminary work is presented to discover a complete protein sequence from…

Quantitative Methods · Quantitative Biology 2008-12-18 Jean-Charles Boisson , Laetitia Jourdan , El-Ghazali Talbi , Christian Rolando

For most deep learning practitioners, sequence modeling is synonymous with recurrent networks. Yet recent results indicate that convolutional architectures can outperform recurrent networks on tasks such as audio synthesis and machine…

Machine Learning · Computer Science 2018-04-20 Shaojie Bai , J. Zico Kolter , Vladlen Koltun

Despite exceptional predictive performance of Deep sequence models (DSMs), the main concern of their deployment centers around the lack of uncertainty awareness. In contrast, probabilistic models quantify the uncertainty associated with…

Machine Learning · Computer Science 2026-03-03 Wenlong Chen

Neural Architecture Search (NAS) methods are widely used in various industries to obtain high quality taskspecific solutions with minimal human intervention. Event Sequences find widespread use in various industrial applications including…

Proteins are sequences of amino acids that serve as the basic building blocks of living organisms. Despite rapidly growing databases documenting structural and functional information for various protein sequences, our understanding of…

Biomolecules · Quantitative Biology 2025-01-06 Weihang Dai

Numerous machine learning (ML) models employed in protein function and structure prediction depend on evolutionary information, which is captured through multiple-sequence alignments (MSA) or position-specific scoring matrices (PSSM) as…

Computational Engineering, Finance, and Science · Computer Science 2024-01-17 Issar Arab

Single-cell RNA sequencing (scRNA-seq) has revolutionized our ability to analyze gene expression at the cellular level. By providing data on gene expression for each individual cell, scRNA-seq generates large datasets with thousands of…

Computational Complexity · Computer Science 2025-02-11 Md Romizul Islam , Swakkhar Shatabda

Protein secondary structure (SS) prediction is important for studying protein structure and function. When only the sequence (profile) information is used as input feature, currently the best predictors can obtain ~80% Q3 accuracy, which…

Biomolecules · Quantitative Biology 2015-12-14 Sheng Wang , Jian Peng , Jianzhu Ma , Jinbo Xu

Spatial proteomics maps protein distributions in tissues, providing transformative insights for life sciences. However, current sequencing-based technologies suffer from low spatial resolution, and substantial inter-tissue variability in…

Quantitative Methods · Quantitative Biology 2025-08-26 Bokai Zhao , Weiyang Shi , Hanqing Chao , Zijiang Yang , Yiyang Zhang , Ming Song , Tianzi Jiang

Sequence labeling (SL) is a fundamental research problem encompassing a variety of tasks, e.g., part-of-speech (POS) tagging, named entity recognition (NER), text chunking, etc. Though prevalent and effective in many downstream applications…

Computation and Language · Computer Science 2020-11-16 Zhiyong He , Zanbo Wang , Wei Wei , Shanshan Feng , Xianling Mao , Sheng Jiang

Recently, automated medical image segmentation methods based on deep learning have achieved great success. However, they heavily rely on large annotated datasets, which are costly and time-consuming to acquire. Few-shot learning aims to…

Artificial Intelligence · Computer Science 2024-08-20 Jiayu Huo , Ruiqiang Xiao , Haotian Zheng , Yang Liu , Sebastien Ourselin , Rachel Sparks

Representation learning is an important step in the machine learning pipeline. Given the current biological sequencing data volume, learning an explicit representation is prohibitive due to the dimensionality of the resulting feature…

Machine Learning · Computer Science 2023-04-04 Sarwan Ali , Usama Sardar , Murray Patterson , Imdad Ullah Khan

Protein sequence classification involves feature selection for accurate classification. Popular protein sequence classification techniques involve extraction of specific features from the sequences. Researchers apply some well-known…

Computational Engineering, Finance, and Science · Computer Science 2012-11-21 Suprativ Saha , Rituparna Chaki

The capability of accurate prediction of protein functions and properties is essential in the biotechnology industry, e.g. drug development and artificial protein synthesis, etc. The main challenges of protein function prediction are the…

Quantitative Methods · Quantitative Biology 2021-12-02 Wei-Cheng Tseng , Po-Han Chi , Jia-Hua Wu , Min Sun

Deep learning methodologies have been employed in several different fields, with an outstanding success in image recognition applications, such as material quality control, medical imaging, autonomous driving, etc. Deep learning models rely…

Computer Vision and Pattern Recognition · Computer Science 2022-03-11 Saul Calderon-Ramirez , Shengxiang Yang , David Elizondo

Understanding sequential information is a fundamental task for artificial intelligence. Current neural networks attempt to learn spatial and temporal information as a whole, limited their abilities to represent large scale spatial…

Computer Vision and Pattern Recognition · Computer Science 2020-06-02 Bo Pang , Kaiwen Zha , Hanwen Cao , Jiajun Tang , Minghui Yu , Cewu Lu

Prototype-based interpretability methods provide intuitive explanations of model prediction by comparing samples to a reference set of memorized exemplars or typical representatives in terms of similarity. In the field of sequential data…

Machine Learning · Computer Science 2023-03-20 Yifei Zhang , Neng Gao , Cunqing Ma

Recently proposed neural network architectures like PointNet [QSMG16] and PointNet++ [QYSG17] have made it possible to apply Deep Learning to 3D point sets. The feature representations of shapes learned by these two networks enabled…

Computer Vision and Pattern Recognition · Computer Science 2025-05-21 Abhimanyu Talwar , Julien Laasri
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