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In molecular communication (MC), molecules are released from the transmitter to convey information. This paper considers a realistic molecule shift keying (MoSK) scenario with two species of molecule in two reservoirs, where the molecules…

Information Theory · Computer Science 2024-04-04 Dongliang Jing , Lin Lin , Andrew W. Eckford

In this paper, we design matched filters for diffusive molecular communication systems taking into account the following impairments: signal-dependent diffusion noise, inter-symbol interference (ISI), and external interfering molecules. The…

Information Theory · Computer Science 2017-05-05 Vahid Jamali , Arman Ahmadzadeh , Robert Schober

Diffusive molecular communications (DiMC) have recently gained attention as a candidate for nano- to micro- and macro-scale communications due to its simplicity and energy efficiency. As signal propagation is solely enabled by Brownian…

Information Theory · Computer Science 2021-01-11 Mustafa Can Gursoy , Masoumeh Nasiri-Kenari , Urbashi Mitra

We consider channels affected by intersymbol interference with reduced-complexity, mutual information optimized, channel-shortening detection. For such settings, we optimize the transmit filter, taking into consideration the reduced…

Information Theory · Computer Science 2013-10-24 Andrea Modenini , Fredrik Rusek , Giulio Colavolpe

This paper focuses on molecular communication (MC) systems using two types of signaling molecules which may participate in a reversible bimolecular reaction in the channel. The motivation for studying these MC systems is that they can…

Information Theory · Computer Science 2019-07-25 Vahid Jamali , Nariman Farsad , Robert Schober , Andrea Goldsmith

This paper focuses on molecular communication (MC) systems where the signaling molecules may participate in a reversible bimolecular reaction in the channel. The motivation for studying these MC systems is that they can realize the concept…

Information Theory · Computer Science 2017-11-02 Vahid Jamali , Nariman Farsad , Robert Schober , Andrea Goldsmith

Intercellular signaling has an important role in organism development, but not all communication occurs using the same mechanism. Here, we analyze the energy efficiency of intercellular signaling by two canonical mechanisms: diffusion of…

Quantitative Methods · Quantitative Biology 2022-11-30 Hyunjoong Kim , Yoichiro Mori , Joshua B. Plotkin

In diffusion-based molecular communication, information is transferred from a transmitter to a receiver using molecular carriers. The low achievable data rate is the main disadvantage of diffusion-based molecular over radio-based…

Emerging Technologies · Computer Science 2018-09-18 Tayyebeh Jahani-Nezhad , Foroogh S. Tabataba

Nano-scale molecular communication is a viable way of exchanging information between nano-machines. In this letter, a low-complexity and non-coherent signal detection technique is proposed to mitigate the inter-symbol-interference (ISI) and…

Emerging Technologies · Computer Science 2015-08-31 Bin Li , Mengwei Sun , Siyi Wang , Weisi Guo , Chenglin Zhao

In molecular communications, the direct detection of signaling molecules may be challenging due to a lack of suitable sensors and interference in the environment. Motivated by research in molecular biology, we investigate an indirect…

Information Theory · Computer Science 2022-04-25 Trang Ngoc Cao , Vahid Jamali , Wayan Wicke , Phee Lep Yeoh , Nikola Zlatanov , Jamie S Evans , Robert Schober

This paper studies the capacity of molecular communications in fluid media, where the information is encoded in the number of transmitted molecules in a time-slot (amplitude shift keying). The propagation of molecules is governed by random…

Information Theory · Computer Science 2016-04-29 Siavash Ghavami , Raviraj Adve , Farshad Lahouti

In diffusion-based communication, as for molecular systems, the achievable data rate is low due to the stochastic nature of diffusion which exhibits a severe inter-symbol-interference (ISI). Multiple-Input Multiple-Output (MIMO)…

Information Theory · Computer Science 2019-04-26 S. M. Reza Rouzegar , Umberto Spagnolini

Inter-symbol interference (ISI) with heteroscedastic, or state-dependent, noise is a defining feature of molecular communication via diffusion (MCvD). However, such noise variance dependency across ISI states has not been systematically…

Information Theory · Computer Science 2026-03-09 Erencem Ozbey , H. Birkan Yilmaz , Chan-Byoung Chae

Iterative message passing detection based on expectation propagation(EP) has demonstrated near-optimum performance in many signal processing and communication scenarios. The method remains feasible even for channel impulse responses (CIRs),…

Information Theory · Computer Science 2025-09-23 Jannis Clausius , Luca Schmid , Laurent Schmalen , Stephan ten Brink

This letter introduces a novel algorithm for generating codebooks in molecular communications (MC). The proposed algorithm utilizes character entropy to effectively mitigate inter-symbol interference (ISI) during MC via diffusion. Based on…

Information Theory · Computer Science 2023-06-07 Haewoong Hyun Changmin Lee , Miaowen Wen , Sang-Hyo Kim , Chan-Byoung Chae

A diffusion-based molecular communication system has two major components: the diffusion in the medium, and the ligand-reception. Information bits, encoded in the time variations of the concentration of molecules, are conveyed to the…

Information Theory · Computer Science 2012-05-23 Arash Einolghozati , Mohsen Sardari , Faramarz Fekri

In the transmission of digital data at a relatively high rate over a particular band limited channel, it is normally necessary to employ an equalizer at the receiver in order to correct the signal distortion introduced by the channel .ISI…

Information Theory · Computer Science 2014-03-18 Laith Awda Kadhim , Salih Mohammed , Osamah Saad

In this paper, we apply dimensional analysis to study a diffusive molecular communication system that uses diffusing enzymes in the propagation environment to mitigate intersymbol interference. The enzymes bind to information molecules and…

Information Theory · Computer Science 2013-11-21 Adam Noel , Karen C. Cheung , Robert Schober

Bistatic Integrated Sensing and Communication (ISAC) is poised to become a cornerstone technology in next-generation communication networks, such as Beyond 5G (B5G) and 6G, by enabling the concurrent execution of sensing and communication…

Signal Processing · Electrical Eng. & Systems 2025-07-15 Yi Wang , Keke Zu , Luping Xiang , Martin Haardt , Chaochao Wang , Xianchao Zhang , Kun Yang

Directional chemosensing is ubiquitous in cell biology, but some cells such as mating yeast paradoxically degrade the signal they aim to detect. While the data processing inequality suggests that such signal modification cannot increase the…

Biological Physics · Physics 2023-10-04 Ryan LeFebre , Joseph A. Landsittel , David E. Stone , Andrew Mugler