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This work presents a new multiphase SPH model that includes the shifting algorithm and a variable smoothing length formalism to simulate multi-phase flows with accuracy and proper interphase management. The implementation was performed in…

This technical note introduces parametric dynamic causal modelling, a method for inferring slow changes in biophysical parameters that control fluctuations of fast neuronal states. The application domain we have in mind is inferring slow…

Quantitative Methods · Quantitative Biology 2020-08-27 Amirhossein Jafarian , Peter Zeidman , Rob. C Wykes , Matthew Walker , Karl J. Friston

Computational fluid dynamics (CFD) is increasingly used to study blood flows in patient-specific arteries for understanding certain cardiovascular diseases. The techniques work quite well for relatively simple problems, but need…

Computational Physics · Physics 2018-10-11 Fande Kong , Vitaly Kheyfets , Ender Finol , Xiao-Chuan Cai

We develop a mixed finite element method for the coupled problem arising in the interaction between a free fluid governed by the Stokes equations and flow in deformable porous medium modeled by the Biot system of poroelasticity. Mass…

Numerical Analysis · Mathematics 2021-12-16 Tongtong Li , Ivan Yotov

Lipid vesicles appear ubiquitously in biological systems. Understanding how the mechanical and intermolecular interations deform vesicle membrane is a fundamental question in biophysics. In this article we developed a fast algorithm to…

Numerical Analysis · Mathematics 2014-11-17 Michael Mikucki , Y. C. Zhou

The automation of ab initio simulations is essential in view of performing high-throughput (HT) computational screenings oriented to the discovery of novel materials with desired physical properties. In this work, we propose algorithms and…

The inherent behavioral variability exhibited by stochastic biochemical systems makes it a challenging task for human experts to manually analyze them. Computational modeling of such systems helps in investigating and predicting the…

Quantitative Methods · Quantitative Biology 2020-01-14 Arfeen Khalid

We propose an efficient simulation algorithm based on the dissipative particle dynamics (DPD) method for studying electrohydrodynamic phenomena in electrolyte fluids. The fluid flow is mimicked with DPD particles while the evolution of the…

Computational Physics · Physics 2015-06-23 Stefan Medina , Jiajia Zhou , Zhen-Gang Wang , Friederike Schmid

This work presents a finite element method for a modified Poisson-Nernst-Planck/Navier-Stokes (PNP/NS) model under the mechanical equilibrium, developed for compressible electrolytes. Another key contribution of this work is the reduction…

Numerical Analysis · Mathematics 2026-01-27 Ankur , Ram Jiwari , Satyvir Singh

In the study of micro-swimmers, both artificial and biological ones, many-query problems arise naturally. Even with the use of advanced high performance computing (HPC), it is not possible to solve this kind of problems in an acceptable…

Numerical Analysis · Mathematics 2020-08-04 Nicola Giuliani , Martin W. Hess , Antonio DeSimone , Gianluigi Rozza

A comprehensive mathematical model of the multiphysics flow of blood and Cerebrospinal Fluid (CSF) in the brain can be expressed as the coupling of a poromechanics system and Stokes' equations: the first describes fluids filtration through…

Numerical Analysis · Mathematics 2023-11-03 Ivan Fumagalli , Mattia Corti , Nicola Parolini , Paola F. Antonietti

The efficient optimization of actuated soft structures, particularly under complex nonlinear forces, remains a critical challenge in advancing robotics. Simulations of nonlinear structures, such as soft-bodied robots modeled using the…

Robotics · Computer Science 2026-02-17 Mathieu Dubied , Paolo Tiso , Robert K. Katzschmann

We study a finite element computational model for solving the coupled problem arising in the interaction between a free fluid and a fluid in a poroelastic medium. The free fluid is governed by the Stokes equations, while the flow in the…

Numerical Analysis · Mathematics 2017-10-19 Ilona Ambartsumyan , Eldar Khattatov , Ivan Yotov , Paolo Zunino

A physics-informed neural network is presented for poroelastic problems with coupled flow and deformation processes. The governing equilibrium and mass balance equations are discussed and specific derivations for two-dimensional cases are…

Computational Engineering, Finance, and Science · Computer Science 2020-10-30 Yared W. Bekele

Neuroscientists fit morphologically and biophysically detailed neuron simulations to physiological data, often using evolutionary algorithms. However, such gradient-free approaches are computationally expensive, making convergence slow when…

Neurons and Cognition · Quantitative Biology 2024-07-23 Ilenna Simone Jones , Konrad Paul Kording

In this paper, we present and analyze a new mixed finite element formulation of a general family of quasi-static multiple-network poroelasticity (MPET) equations. The MPET equations describe flow and deformation in an elastic porous medium…

Numerical Analysis · Mathematics 2018-04-23 Jeonghun J. Lee , Eleonora Piersanti , Kent-Andre Mardal , Marie E. Rognes

In this paper, we present a 2D numerical model developed to simulate the dynamics of soft, deformable particles. To accommodate significant particle deformations, the particle surface is represented as a narrow shell composed of mass points…

Computational Physics · Physics 2025-04-01 Yohann Trivino , Vincent Richefeu , Farhang Radjai , Komlanvi Lampoh , Jean-Yves Delenne

Imaging the bio-impedance distribution of a biological sample can provide understandings about the sample's electrical properties which is an important indicator of physiological status. This paper presents a multi-frequency electromagnetic…

Applied Physics · Physics 2020-07-29 Jinxi Xiang , Zhou Chen , Yonggui Dong , Yunjie Yang

Accurate compensation of brain deformation is a critical challenge for reliable image-guided neurosurgery, as surgical manipulation and tumor resection induce tissue motion that misaligns preoperative planning images with intraoperative…

Physics-informed neural network architectures have emerged as a powerful tool for developing flexible PDE solvers which easily assimilate data, but face challenges related to the PDE discretization underpinning them. By instead adapting a…

Numerical Analysis · Mathematics 2020-12-11 Ravi G. Patel , Indu Manickam , Nathaniel A. Trask , Mitchell A. Wood , Myoungkyu Lee , Ignacio Tomas , Eric C. Cyr
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