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Random-effects meta-analyses have been widely applied in evidence synthesis for various types of medical studies. However, standard inference methods (e.g. restricted maximum likelihood estimation) usually underestimate statistical errors…

Methodology · Statistics 2019-05-13 Shonosuke Sugasawa , Hisashi Noma

Network meta-analysis of diagnostic test accuracy (NMA-DTA) is a relatively new field, involving combining evidence across studies to evaluate and compare the accuracy of different tests for a given condition. However, the methods proposed…

Methodology · Statistics 2026-04-23 Efthymia Derezea , Gabriel Rogers , Nicky J Welton , Hayley E Jones

Multivariate meta-analysis is gaining prominence in evidence synthesis research because it enables simultaneous synthesis of multiple correlated outcome data, and random-effects models have generally been used for addressing between-studies…

Methodology · Statistics 2021-07-14 Hisashi Noma , Kengo Nagashima , Toshi A. Furukawa

Confidence region prediction is a practically useful extension to the commonly studied pattern recognition problem. Instead of predicting a single label, the constraint is relaxed to allow prediction of a subset of labels given a desired…

Machine Learning · Computer Science 2024-05-27 David Lindsay , Sian Lindsay

In diagnostic test accuracy meta-analysis (DTA-MA), standard inference methods using bivariate random-effects models for jointly synthesizing sensitivity and specificity can be sensitive to outlying studies and may yield misleading…

Methodology · Statistics 2026-05-01 Kotaro Sasaki , Hisashi Noma , Theodoros Evrenoglou

Background: Subgroup analyses and meta-regression are commonly used to investigate heterogeneity in diagnostic test accuracy (DTA) meta-analyses (MA), but adherence to methodological guidance is unclear. This methodological review…

Introduction: Despite their applicability, statistical models used for the meta-analysis of test accuracy require specialised knowledge to implement, with the necessary level of expertise having recently increased. This is due to the…

Applications · Statistics 2022-11-16 Enzo Cerullo , Alex J. Sutton , Hayley E. Jones , Olivia Wu , Terry J. Quinn , Nicola J. Cooper

We propose a methodology for constructing confidence regions with partially identified models of general form. The region is obtained by inverting a test of internal consistency of the econometric structure. We develop a dilation bootstrap…

Econometrics · Economics 2021-02-10 Alfred Galichon , Marc Henry

We propose a new inferential framework for constructing confidence regions and testing hypotheses in statistical models specified by a system of high dimensional estimating equations. We construct an influence function by projecting the…

Statistics Theory · Mathematics 2016-06-24 Matey Neykov , Yang Ning , Jun S. Liu , Han Liu

Conventional test-time adaptation (TTA) approaches typically adapt the model using only a small fraction of test samples, often those with low-entropy predictions, thereby failing to fully leverage the available information in the test…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Nam Nguyen Phuong , Duc Nguyen The Minh , Phi Le Nguyen , Ehsan Abbasnejad , Minh Hoai

Meta-analyses of diagnostic test accuracy (DTA) studies have been gaining prominence in research in clinical epidemiology and health technology development. In these DTA meta-analyses, some studies may have markedly different…

Methodology · Statistics 2021-07-14 Yuki Matsushima , Hisashi Noma , Tomohide Yamada , Toshi A. Furukawa

Wild Test-Time Adaptation (WTTA) is proposed to adapt a source model to unseen domains under extreme data scarcity and multiple shifts. Previous approaches mainly focused on sample selection strategies, while overlooking the fundamental…

Computer Vision and Pattern Recognition · Computer Science 2025-06-05 Zixuan Hu , Yichun Hu , Xiaotong Li , Shixiang Tang , Ling-Yu Duan

In this study, we introduce an intelligent Test Time Augmentation (TTA) algorithm designed to enhance the robustness and accuracy of image classification models against viewpoint variations. Unlike traditional TTA methods that…

Image and Video Processing · Electrical Eng. & Systems 2024-06-14 Efe Ozturk , Mohit Prabhushankar , Ghassan AlRegib

Meta-analysis can be formulated as combining $p$-values across studies into a joint $p$-value function, from which point estimates and confidence intervals can be derived. We extend the meta-analytic estimation framework based on combined…

Methodology · Statistics 2025-10-21 David Kronthaler , Leonhard Held

Test-time adaptation (TTA) seeks to tackle potential distribution shifts between training and test data by adapting a given model w.r.t. any test sample. Although recent TTA has shown promising performance, we still face two key challenges:…

Machine Learning · Computer Science 2025-08-27 Mingkui Tan , Guohao Chen , Jiaxiang Wu , Yifan Zhang , Yaofo Chen , Peilin Zhao , Shuaicheng Niu

We propose a novel statistical method for testing the results of anomaly detection (AD) under domain adaptation (DA), which we call CAD-DA -- controllable AD under DA. The distinct advantage of the CAD-DA lies in its ability to control the…

Machine Learning · Statistics 2023-10-24 Vo Nguyen Le Duy , Hsuan-Tien Lin , Ichiro Takeuchi

There have been reports of correlation between estimates of prevalence and test accuracy across studies included in diagnostic meta-analyses. It has been hypothesized that this unexpected association arises because of certain biases…

Methodology · Statistics 2025-08-15 Yang Lu , Robert Platt , Nandini Dendukuri

Diagnostic accuracy studies assess sensitivity and specificity of a new index test in relation to an established comparator or the reference standard. The development and selection of the index test is usually assumed to be conducted prior…

Methodology · Statistics 2022-08-30 Max Westphal , Antonia Zapf

The present study investigates the performance of several statistical tests to detect publication bias in diagnostic meta-analysis by means of simulation. While bivariate models should be used to pool data from primary studies in diagnostic…

Methodology · Statistics 2022-11-24 Paul-Christian Bürkner , Philipp Doebler

The area under the curve (AUC) of summary receiver operating characteristic (SROC) curve is a primary statistical outcome for meta-analysis of diagnostic test accuracy studies (DTA). However, its confidence interval has not been reported in…

Applications · Statistics 2022-08-02 Hisashi Noma , Yuki Matsushima , Ryota Ishii
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