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The interpretation of medical images is a challenging task, often complicated by the presence of artifacts, occlusions, limited contrast and more. Most notable is the case of chest radiography, where there is a high inter-rater variability…

Chest radiography is the most common radiographic examination performed in daily clinical practice for the detection of various heart and lung abnormalities. The large amount of data to be read and reported, with more than 100 studies per…

Computer Vision and Pattern Recognition · Computer Science 2021-04-22 Sebastian Gündel , Arnaud A. A. Setio , Florin C. Ghesu , Sasa Grbic , Bogdan Georgescu , Andreas Maier , Dorin Comaniciu

Chest X-ray (CXR) is the most common X-ray examination performed in daily clinical practice for the diagnosis of various heart and lung abnormalities. The large amount of data to be read and reported, with 100+ studies per day for a single…

Computer Vision and Pattern Recognition · Computer Science 2019-05-17 Sebastian Guendel , Florin C. Ghesu , Sasa Grbic , Eli Gibson , Bogdan Georgescu , Andreas Maier , Dorin Comaniciu

Machine learning models for radiology benefit from large-scale data sets with high quality labels for abnormalities. We curated and analyzed a chest computed tomography (CT) data set of 36,316 volumes from 19,993 unique patients. This is…

Image and Video Processing · Electrical Eng. & Systems 2020-10-14 Rachel Lea Draelos , David Dov , Maciej A. Mazurowski , Joseph Y. Lo , Ricardo Henao , Geoffrey D. Rubin , Lawrence Carin

Chest x-rays are the most common radiology studies for diagnosing lung and heart disease. Hence, a system for automated pre-reporting of pathologic findings on chest x-rays would greatly enhance radiologists' productivity. To this end, we…

Image and Video Processing · Electrical Eng. & Systems 2020-06-15 Adora M. DSouza , Anas Z. Abidin , Axel Wismüller

A major obstacle to the integration of deep learning models for chest x-ray interpretation into clinical settings is the lack of understanding of their failure modes. In this work, we first investigate whether there are patient subgroups…

Computer Vision and Pattern Recognition · Computer Science 2021-07-21 Emma Chen , Andy Kim , Rayan Krishnan , Jin Long , Andrew Y. Ng , Pranav Rajpurkar

Overconfidence in deep learning models poses a significant risk in high-stakes medical imaging tasks, particularly in multi-label classification of chest X-rays, where multiple co-occurring pathologies must be detected simultaneously. This…

Image and Video Processing · Electrical Eng. & Systems 2025-09-15 Yehudit Aperstein , Amit Tzahar , Alon Gottlib , Tal Verber , Ravit Shagan Damti , Alexander Apartsin

Automating chest radiograph interpretation using Deep Learning (DL) models has the potential to significantly improve clinical workflows, decision-making, and large-scale health screening. However, in medical settings, merely optimising…

Computation and Language · Computer Science 2025-05-08 Gianluca Manzo , Julia Ive

Chest radiography is one of the most common types of diagnostic radiology exams, which is critical for screening and diagnosis of many different thoracic diseases. Specialized algorithms have been developed to detect several specific…

Image and Video Processing · Electrical Eng. & Systems 2020-06-15 Hieu H. Pham , Tung T. Le , Dat Q. Tran , Dat T. Ngo , Ha Q. Nguyen

Background: Chest X-rays are the most commonly performed, cost-effective diagnostic imaging tests ordered by physicians. A clinically validated AI system that can reliably separate normals from abnormals can be invaluble particularly in…

Objectives To develop and validate a deep learning-based diagnostic model incorporating uncertainty estimation so as to facilitate radiologists in the preoperative differentiation of the pathological subtypes of renal cell carcinoma (RCC)…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Ni Yao , Hang Hu , Kaicong Chen , Chen Zhao , Yuan Guo , Boya Li , Jiaofen Nan , Yanting Li , Chuang Han , Fubao Zhu , Weihua Zhou , Li Tian

Reliable uncertainty quantification is crucial for trustworthy decision-making and the deployment of AI models in medical imaging. While prior work has explored the ability of neural networks to quantify predictive, epistemic, and aleatoric…

Machine Learning · Statistics 2025-08-07 Simon Baur , Wojciech Samek , Jackie Ma

The chest X-rays (CXRs) is one of the views most commonly ordered by radiologists (NHS),which is critical for diagnosis of many different thoracic diseases. Accurately detecting thepresence of multiple diseases from CXRs is still a…

Computer Vision and Pattern Recognition · Computer Science 2020-05-27 Hieu H. Pham , Tung T. Le , Dat T. Ngo , Dat Q. Tran , Ha Q. Nguyen

With the development of deep learning-based methods, automated classification of electrocardiograms (ECGs) has recently gained much attention. Although the effectiveness of deep neural networks has been encouraging, the lack of information…

Signal Processing · Electrical Eng. & Systems 2022-03-02 Wenrui Zhang , Xinxin Di , Guodong Wei , Shijia Geng , Zhaoji Fu , Shenda Hong

Large, labeled datasets have driven deep learning methods to achieve expert-level performance on a variety of medical imaging tasks. We present CheXpert, a large dataset that contains 224,316 chest radiographs of 65,240 patients. We design…

Prediction uncertainty estimation has clinical significance as it can potentially quantify prediction reliability. Clinicians may trust 'blackbox' models more if robust reliability information is available, which may lead to more models…

Machine Learning · Computer Science 2022-10-04 Michael Dohopolski , Kai Wang , Biling Wang , Ti Bai , Dan Nguyen , David Sher , Steve Jiang , Jing Wang

Patients undergoing chest X-rays (CXR) often endure multiple lung diseases. When evaluating a patient's condition, due to the complex pathologies, subtle texture changes of different lung lesions in images, and patient condition…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Mengliang Zhang , Xinyue Hu , Lin Gu , Liangchen Liu , Kazuma Kobayashi , Tatsuya Harada , Ronald M. Summers , Yingying Zhu

We propose a novel deep neural network architecture for normalcy detection in chest X-ray images. This architecture treats the problem as fine-grained binary classification in which the normal cases are well-defined as a class while leaving…

The precision of contouring target structures and organs-at-risk (OAR) in radiotherapy planning is crucial for ensuring treatment efficacy and patient safety. Recent advancements in deep learning (DL) have significantly improved OAR…

Image and Video Processing · Electrical Eng. & Systems 2024-09-30 Marvin Tom Teichmann , Manasi Datar , Lisa Kratzke , Fernando Vega , Florin C. Ghesu

We propose an automated method based on deep learning to compute the cardiothoracic ratio and detect the presence of cardiomegaly from chest radiographs. We develop two separate models to demarcate the heart and chest regions in an X-ray…

Image and Video Processing · Electrical Eng. & Systems 2021-01-20 Tanveer Gupte , Mrunmai Niljikar , Manish Gawali , Viraj Kulkarni , Amit Kharat , Aniruddha Pant
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