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Recent studies have demonstrated the advantages of fractional-order calculus tools for probing the viscoelastic properties of collagenous tissue, characterizing the arterial blood flow and red cell membrane mechanics, and modeling the…

Systems and Control · Electrical Eng. & Systems 2020-10-21 Mohamed A. Bahloul , Taous-Meriem Laleg Kirati

The automatic analysis of ultrasound sequences can substantially improve the efficiency of clinical diagnosis. In this work we present our attempt to automate the challenging task of measuring the vascular diameter of the fetal abdominal…

Computer Vision and Pattern Recognition · Computer Science 2018-07-12 Nicolo' Savioli , Silvia Visentin , Erich Cosmi , Enrico Grisan , Pablo Lamata , Giovanni Montana

Purpose: To introduce and evaluate TrueLung, an automated pipeline for computation and analysis of free-breathing and contrast-agent free pulmonary functional MRI. Material and Methods: time-resolved ultra-fast bSSFP acquisitions are…

The brain perfusion ROI detection being a preliminary step, designed to exclude non-brain tissues from analyzed DSC perfusion MR images. Its accuracy is considered as the key factor for delivering correct results of perfusion data analysis.…

Medical Physics · Physics 2024-05-15 Svitlana Alkhimova , Svitlana Sliusar

Background and Objective: This proof of concept study investigates mathematical modelling of blood flow and oxygen transport in cerebral microcirculation, focusing on understanding hemodynamic responses. By coupling oxygen transport models…

Numerical Analysis · Mathematics 2024-11-19 Maryam Samavaki , Santtu Söderholm , Arash Zarrin Nia , Sampsa Pursiainen

Near infrared spectroscopy (NIRS) is an imaging-based diagnostic tool that provides non-invasive and continuous evaluation of regional tissue oxygenation in real-time. In recent years, NIRS has show promise as a useful monitoring technology…

Applications · Statistics 2018-09-18 Ying Guo , Yikai Wang , Terri Marin , Easley Kirk , Ravi M. Patel , Cassandra D. Josephson

Superparamagnetic iron oxide nanoparticles (SPIONs) such as ferumoxytol are promising theranostic agents detectable with MRI. Relaxation time mapping offers reproducible, quantitative biomarkers of SPION distribution, but conventional…

Premature births can lead to complications, with fetal lung immaturity being a primary concern. Currently, fetal lung maturity (FLM) requires an invasive surfactant extraction procedure between the 32nd and 39th weeks of pregnancy.…

Medical Physics · Physics 2023-07-21 Márton Á. Goda , Ron Beloosesky , Chen Ben David , Zeev Weiner , Joachim A. Behar

4D flow magnetic resonance imaging (MRI) is a reliable, non-invasive approach for estimating blood flow velocities, vital for cardiovascular diagnostics. Unlike conventional MRI focused on anatomical structures, 4D flow MRI requires high…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Sun Jo , Seok Young Hong , JinHyun Kim , Seungmin Kang , Ahjin Choi , Don-Gwan An , Simon Song , Je Hyeong Hong

Perfusion imaging is crucial in acute ischemic stroke for quantifying the salvageable penumbra and irreversibly damaged core lesions. As such, it helps clinicians to decide on the optimal reperfusion treatment. In perfusion CT imaging,…

Image and Video Processing · Electrical Eng. & Systems 2022-04-27 Ezequiel de la Rosa , Diana M. Sima , Bjoern Menze , Jan S. Kirschke , David Robben

Ultrashort laser pulses enable attosecond-scale measurements and drive breakthroughs across science and technology, but their routine use hinges on reliable pulse characterization. Frequency-Resolved Optical Gating (FROG) is a leading…

Optics · Physics 2026-04-29 Abhimanyu Borthakur , Jack Eden Hirschman , Sergio Carbajo

Recent development of quantitative myocardial blood flow (MBF) mapping allows direct evaluation of absolute myocardial perfusion, by computing pixel-wise flow maps. Clinical studies suggest quantitative evaluation would be more desirable…

Quantitative Methods · Quantitative Biology 2020-06-01 Hui Xue , Rhodri Davies , Louis AE Brown , Kristopher D Knott , Tushar Kotecha , Marianna Fontana , Sven Plein , James C Moon , Peter Kellman

Trajectory forecasting in healthcare data has been an important area of research in precision care and clinical integration for computational methods. In recent years, generative AI models have demonstrated promising results in capturing…

Signal Processing · Electrical Eng. & Systems 2024-12-09 Rosemary Y. He , Jeffrey N. Chiang

Deep generative models provide a promising approach to de novo 3D peptide design. Most of them jointly model the distributions of peptide's position, orientation, and conformation, attempting to simultaneously converge to the target pocket.…

Quantitative Methods · Quantitative Biology 2025-11-04 Dengdeng Huang , Shikui Tu

Arterial spin labeling (ASL) magnetic resonance imaging (MRI) enables cerebral perfusion measurement, which is crucial in detecting and managing neurological issues in infants born prematurely or after perinatal complications. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Christoforos Galazis , Ching-En Chiu , Tomoki Arichi , Anil A. Bharath , Marta Varela

High-fidelity numerical simulations of chaotic, high dimensional nonlinear dynamical systems are computationally expensive, necessitating the development of efficient surrogate models. Most surrogate models for such systems are…

Machine Learning · Computer Science 2026-03-16 Dibyajyoti Chakraborty , Hojin Kim , Romit Maulik

The placenta plays a crucial role in fetal development. Automated 3D placenta segmentation from fetal EPI MRI holds promise for advancing prenatal care. This paper proposes an effective semi-supervised learning method for improving placenta…

Computer Vision and Pattern Recognition · Computer Science 2023-10-17 Yingcheng Liu , Neerav Karani , Neel Dey , S. Mazdak Abulnaga , Junshen Xu , P. Ellen Grant , Esra Abaci Turk , Polina Golland

Background: Pleural Effusions (PE) is a common finding in many different clinical conditions, but accurately measuring their volume from CT scans is challenging. Purpose: To improve PE segmentation and quantification for enhanced clinical…

Image and Video Processing · Electrical Eng. & Systems 2025-10-07 Sanhita Basu , Tomas Fröding , Ali Teymur Kahraman , Dimitris Toumpanakis , Tobias Sjöblom

The fully automated and relatively accurate method of brain tissues segmentation on T2-weighted magnetic resonance perfusion images is proposed. Segmentation with this method provides a possibility to obtain perfusion region of interest on…

Image and Video Processing · Electrical Eng. & Systems 2024-05-15 S. M. Alkhimova , A. P. Krenevych

In utero diffusion MRI provides unique opportunities to non-invasively study the microstructure of tissue during fetal development. A wide range of developmental processes, such as the growth of white matter tracts in the brain, the…