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One of the main challenges in drug discovery is to find molecules that bind specifically and strongly to their target protein while having minimal binding to other proteins. By predicting binding affinity, it is possible to identify the…

Quantum Physics · Physics 2023-01-19 L. Domingo , M. Djukic , C. Johnson , F. Borondo

Quantum machine learning provides a fundamentally different approach to analyzing data. However, many interesting datasets are too complex for currently available quantum computers. Present quantum machine learning applications usually…

Experimental demonstration of the quantum advantage over classical simulations with Boson Sampling is currently under intensive investigation. There seems to be a scalability issue to the necessary number of bosons on the linear optical…

Quantum Physics · Physics 2021-09-07 Valery Shchesnovich

Traditional quantum system control methods often face different constraints, and are easy to cause both leakage and stochastic control errors under the condition of limited resources. Reinforcement learning has been proved as an efficient…

Emerging Technologies · Computer Science 2024-05-14 Wenjie Liu , Bosi Wang , Jihao Fan , Yebo Ge , Mohammed Zidan

We develop and implement two realizations of quantum graph neural networks (QGNN), applied to the task of particle interaction simulation. The first QGNN is a speculative quantum-classical hybrid learning model that relies on the ability to…

We propose a scheme leveraging reinforcement learning to engineer control fields for generating non-classical states. It is exemplified by the application to prepare spin-squeezed states for an open collective spin model where a linear…

Quantum Physics · Physics 2024-06-17 X. L. Zhao , Y. M. Zhao , M. Li , T. T. Li , Q. Liu , S. Guo , X. X. Yi

The topic of generative learning has gained traction within the field of quantum machine learning, in particular with the advent of train-on-classical, deploy-on-quantum methods. This approach exploits the properties of…

Quantum Physics · Physics 2026-03-11 Felix Gottlieb , Rawad Mezher , Brian Ventura , Shane Mansfield , Alexia Salavrakos

Current experimental quantum computing devices are limited by noise, mainly originating from entangling gates. If an efficient gate sequence for an operation is unknown, one often employs layered parameterized quantum circuits, especially…

Quantum Physics · Physics 2025-11-12 Tom R. Rieckmann , Stefan Scheel , A. Douglas K. Plato

Can near-term gate model based quantum processors offer quantum advantage for practical applications in the pre-fault tolerance noise regime? A class of algorithms which have shown some promise in this regard are the so-called…

Quantum Physics · Physics 2019-08-13 Guillaume Verdon , Michael Broughton , Jacob Biamonte

An application of quantum cloning to optimally interface a quantum system with a classical observer is presented, in particular we describe a procedure to perform a minimal disturbance measurement on a single qubit by adopting a 1->2…

Quantum Physics · Physics 2009-11-11 M. Ricci , F. Sciarrino , N. J. Cerf , R. Filip , J. Fiurasek , F. De Martini

Reinforcement learning has emerged as a promising methodology for training robot controllers. However, most results have been limited to simulation due to the need for a large number of samples and the lack of automated-yet-safe data…

Robotics · Computer Science 2018-03-29 Kendall Lowrey , Svetoslav Kolev , Jeremy Dao , Aravind Rajeswaran , Emanuel Todorov

Quantum computers promise tremendous impact across applications -- and have shown great strides in hardware engineering -- but remain notoriously error prone. Careful design of low-level controls has been shown to compensate for the…

Quantum annealing (QA) has attracted research interest as a sampler and combinatorial optimization problem (COP) solver. A recently proposed sampling-based solver for QA significantly reduces the required number of qubits, being capable of…

Quantum Physics · Physics 2025-07-31 Ryo Hagiwara , Shunta Arai , Satoshi Takabe

The search for an application of near-term quantum devices is widespread. Quantum Machine Learning is touted as a potential utilisation of such devices, particularly those which are out of the reach of the simulation capabilities of…

Quantum Physics · Physics 2021-04-28 Brian Coyle , Daniel Mills , Vincent Danos , Elham Kashefi

In this work, we give a hybrid quantum-classical algorithm for solving electronic structure problems of molecules using only linear quantum optical systems. The variational ansatz we proposed is a hybrid of non-interacting Boson dynamics…

The standard quantum annealing algorithm tries to approach the ground state of a classical system by slowly decreasing the hopping rates of a quantum random walk in the configuration space of the problem, where the on-site energies are…

Disordered Systems and Neural Networks · Physics 2018-12-26 A. Ramezanpour

Quantum computers have the opportunity to be transformative for a variety of computational tasks. Recently, there have been proposals to use the unsimulatably of large quantum devices to perform regression, classification, and other machine…

Boson sampling, a computational problem conjectured to be hard to simulate on a classical machine, is a promising candidate for an experimental demonstration of quantum advantage using bosons. However, inevitable experimental noise and…

Quantum Physics · Physics 2022-10-12 Gabriele Bressanini , Hyukjoon Kwon , M. S. Kim

We combine classical and quantum Machine Learning (ML) techniques to effectively analyze long time-series data acquired during experiments. Specifically, we demonstrate that replacing a deep classical neural network with a thoughtfully…

Quantum Physics · Physics 2025-04-10 G. Maragkopoulos , N. Stefanakos , A. Mandilara , D. Syvridis

Recently, increased computational power and data availability, as well as algorithmic advances, have led machine learning techniques to impressive results in regression, classification, data-generation and reinforcement learning tasks.…