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Related papers: Simulated Epidemics in 3D Protein Structures to De…

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Generating molecules that bind to specific proteins is an important but challenging task in drug discovery. Previous works usually generate atoms in an auto-regressive way, where element types and 3D coordinates of atoms are generated one…

Biomolecules · Quantitative Biology 2024-07-16 Haitao Lin , Yufei Huang , Odin Zhang , Siqi Ma , Meng Liu , Xuanjing Li , Lirong Wu , Jishui Wang , Tingjun Hou , Stan Z. Li

We present a sequence-based probabilistic formalism that directly addresses co-operative effects in networks of interacting positions in proteins, providing significantly improved contact prediction, as well as accurate quantitative…

Quantitative Methods · Quantitative Biology 2012-07-12 Alan Lapedes , Bertrand Giraud , Christopher Jarzynski

Capturing the structured mixing within a population is key to the reliable projection of infectious disease dynamics and hence informed control. Both heterogeneity in the number of contacts and age-structured mixing have been repeatedly…

Social and Information Networks · Computer Science 2026-03-17 Luke Murray Kearney , Emma L Davis , Matt J Keeling

We study the impact of contact heterogeneity on epidemic dynamics. A system characterized by multiple susceptible populations is considered. The description of the spread of an infectious disease is obtained through the study of a system of…

Physics and Society · Physics 2021-11-11 Andrea Medaglia , Mattia Zanella

This paper introduces a new approach to describe the spread of research topics across disciplines using epidemic models. The approach is based on applying individual-based models from mathematical epidemiology to the diffusion of a research…

Physics and Society · Physics 2009-05-25 Istvan Z. Kiss , Mark Broom , Paul Craze , Ismael Rafols

Disease spread in most biological populations requires the proximity of agents. In populations where the individuals have spatial mobility, the contact graph is generated by the "collision dynamics" of the agents, and thus the evolution of…

Physics and Society · Physics 2007-06-07 Z. Toroczkai , H. Guclu

The abrupt outbreak and transmission of biological diseases has always been a long-time concern of humankind. For long, mathematical modeling has served as a simple and yet efficient tool to investigate, predict, and control spread of…

Populations and Evolution · Quantitative Biology 2020-04-10 Aresh Dadlani , Richard O. Afolabi , Hyoyoung Jung , Khosrow Sohraby , Kiseon Kim

A common theme among the proposed models for network epidemics is the assumption that the propagating object, i.e., a virus or a piece of information, is transferred across the nodes without going through any modification or evolution.…

Physics and Society · Physics 2019-11-05 Rashad Eletreby , Yong Zhuang , Kathleen M. Carley , Osman Yağan , H. Vincent Poor

can evolve simultaneously. For the information-driven adaptive process, susceptible (infected) individuals who have abilities to recognize the disease would break the links of their infected (susceptible) neighbors to prevent the epidemic…

Physics and Society · Physics 2015-05-20 Xiu-Xiu Zhan , Chuang Liu , Gui-Quan Sun , Zi-Ke Zhang

The spread of an infectious disease depends on intrinsic properties of the disease as well as the connectivity and actions of the population. This study investigates the dynamics of an SIR type model which accounts for human tendency to…

Dynamical Systems · Mathematics 2021-07-26 Hannah Scanlon , John Gemmer

Compartmental models of epidemics are widely used to forecast the effects of communicable diseases such as COVID-19 and to guide policy. Although it has long been known that such processes take place on social networks, the assumption of…

Physics and Society · Physics 2024-03-14 Samuel Johnson

Recently, motivated by the pioneer works that reveal the small-world effect and scale-free property of various real-life networks, many scientists devote themselves into studying complex networks. One of the ultimate goals is to understand…

Physics and Society · Physics 2007-05-23 Tao Zhou , Zhong-Qian Fu , Bing-Hong Wang

The science of networks has revolutionised research into the dynamics of interacting elements. It could be argued that epidemiology in particular has embraced the potential of network theory more than any other discipline. Here we review…

The evolutionary trajectory of a protein through sequence space is constrained by function and three-dimensional (3D) structure. Residues in spatial proximity tend to co-evolve, yet attempts to invert the evolutionary record to identify…

Biomolecules · Quantitative Biology 2015-03-13 Debora S. Marks , Lucy J. Colwell , Robert Sheridan , Thomas A. Hopf , Andrea Pagnani , Riccardo Zecchina , Chris Sander

The spontaneous behavioral changes of the agents during an epidemic can have significant effects on the delay and the prevalence of its spread. In this work, we study a social distancing game among the agents of a population, who determine…

Physics and Society · Physics 2020-07-13 A. -R. Lagos , I. Kordonis , G. P. Papavassilopoulos

Most previous studies of epidemic dynamics on complex networks suppose that the disease will eventually stabilize at either a disease-free state or an endemic one. In reality, however, some epidemics always exhibit sporadic and recurrent…

Physics and Society · Physics 2013-11-19 Xiao-Long Peng , Michael Small , Xin-Jian Xu , Xinchu Fu

Diffusion processes in networks are increasingly used to model the spread of information and social influence. In several applications in computational sustainability such as the spread of wildlife, infectious diseases and traffic mobility…

Social and Information Networks · Computer Science 2013-09-27 Akshat Kumar , Daniel Sheldon , Biplav Srivastava

The importance of modeling the spread of epidemics through a population has led to the development of mathematical models for infectious disease propagation. A number of empirical studies have collected and analyzed data on contacts between…

Social and Information Networks · Computer Science 2017-07-28 Rehan Ahmad , Kevin S. Xu

Consider stochastic models for the spread of an infection in a structured community, where this structured community is itself described by a random network model. Some common network models and transmission models are defined and large…

Populations and Evolution · Quantitative Biology 2019-08-16 Tom Britton

We investigate a model for spatial epidemics explicitly taking into account bi-directional movements between base and destination locations on individual mobility networks. We provide a systematic analysis of generic dynamical features of…

Physics and Society · Physics 2012-03-07 Vitaly Belik , Theo Geisel , Dirk Brockmann
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