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Lung tumors, especially those located close to or surrounded by soft tissues like the mediastinum, are difficult to segment due to the low soft tissue contrast on computed tomography images. Magnetic resonance images contain superior…

Image and Video Processing · Electrical Eng. & Systems 2019-09-11 Jue Jiang , Jason Hu , Neelam Tyagi , Andreas Rimner , Sean L. Berry , Joseph O. Deasy , Harini Veeraraghavan

Cancer is one of the leading causes of death globally, and early diagnosis is crucial for patient survival. Deep learning algorithms have great potential for automatic cancer analysis. Artificial intelligence has achieved high performance…

Image and Video Processing · Electrical Eng. & Systems 2024-04-16 Monika Górka , Daniel Jaworek , Marek Wodzinski

Manual or automatic delineation of the esophageal tumor in CT images is known to be very challenging. This is due to the low contrast between the tumor and adjacent tissues, the anatomical variation of the esophagus, as well as the…

Breast CT provides image volumes with isotropic resolution in high contrast, enabling detection of small calcification (down to a few hundred microns in size) and subtle density differences. Since breast is sensitive to x-ray radiation,…

Image and Video Processing · Electrical Eng. & Systems 2020-11-05 Huidong Xie , Hongming Shan , Wenxiang Cong , Chi Liu , Xiaohua Zhang , Shaohua Liu , Ruola Ning , Ge Wang

This study proposes a novel imaging and reconstruction framework for dual-energy cone-beam CT (DECBCT) using only two orthogonal X-ray projections at different energy levels (2V-DECBCT). The goal is to enable fast and low-dose DE volumetric…

Medical Physics · Physics 2025-04-18 Junbo Peng , Tonghe Wang , Shaoyan Pan , Xiaofeng Yang

Dual spectral computed tomography (DSCT) can achieve energy- and material-selective images, and has a superior distinguishability of some materials than conventional single spectral computed tomography (SSCT). However, the decomposition…

Optimization and Control · Mathematics 2017-11-22 Qian Wang

Defect engineering has been profoundly employed to confer desirable functionality to materials that pristine lattices inherently lack. Although single atomic-resolution scanning transmission electron microscopy (STEM) images are widely…

Accurate quantification in positron emission tomography (PET) is essential for accurate diagnostic results and effective treatment tracking. A major issue encountered in PET imaging is attenuation. Attenuation refers to the diminution of…

Contrast-enhanced computed tomography angiograms (CTAs) are widely used in cardiovascular imaging to obtain a non-invasive view of arterial structures. However, contrast agents are associated with complications at the injection site as well…

Image and Video Processing · Electrical Eng. & Systems 2020-03-04 Anirudh Chandrashekar , Ashok Handa , Natesh Shivakumar , Pierfrancesco Lapolla , Vicente Grau , Regent Lee

The use of dual-energy CT (DECT) potentially decreases range uncertainties in proton and ion therapy treatment planning via determination of the involved physical target quantities. For eventual clinical application, the correct treatment…

Medical Physics · Physics 2016-05-19 Christian Möhler , Patrick Wohlfahrt , Christian Richter , Steffen Greilich

Computed tomography (CT) is increasingly being used for cancer screening, such as early detection of lung cancer. However, CT studies have varying pixel spacing due to differences in acquisition parameters. Thick slice CTs have lower…

Computer Vision and Pattern Recognition · Computer Science 2018-07-19 Meng Li , Shiwen Shen , Wen Gao , William Hsu , Jason Cong

Background: Dual-energy (DE) imaging techniques in cone-beam computed tomography (CBCT) have potential clinical applications, including material quantification and improved tissue visualization. However, the performance of DE CBCT is…

Medical Physics · Physics 2023-06-26 Cem Altunbas

In dual-energy computed tomography (DECT), low- and high- kVp data are collected often over a full-angular range (FAR) of $360^\circ$. While there exists strong interest in DECT with low- and high-kVp data acquired over limited-angular…

Medical Physics · Physics 2021-08-17 Buxin Chen , Zheng Zhang , Dan Xia , Emil Y. Sidky , Xiaochuan Pan

Early detection of lung cancer is essential in reducing mortality. Recent studies have demonstrated the clinical utility of low-dose computed tomography (CT) to detect lung cancer among individuals selected based on very limited clinical…

Computer Vision and Pattern Recognition · Computer Science 2019-02-25 Jiachen Wang , Riqiang Gao , Yuankai Huo , Shunxing Bao , Yunxi Xiong , Sanja L. Antic , Travis J. Osterman , Pierre P. Massion , Bennett A. Landman

Quantitative estimation of contrast agent concentration is made possible by spectral CT and material decomposition. There are several approaches to modulate the sensitivity of the imaging system to obtain the different spectral channels…

Medical Physics · Physics 2020-10-16 Matthew Tivnan , Wenying Wang , Grace Gang , Eleni Liapi , Peter Noel , J. Webster Stayman

Low-dose CT denoising is a challenging task that has been studied by many researchers. Some studies have used deep neural networks to improve the quality of low-dose CT images and achieved fruitful results. In this paper, we propose a deep…

Image and Video Processing · Electrical Eng. & Systems 2019-02-28 Maryam Gholizadeh-Ansari , Javad Alirezaie , Paul Babyn

Dual-energy computed tomography (DECT) utilizes separate X-ray energy spectra to improve multi-material decomposition (MMD) for various diagnostic applications. However accurate decomposing more than two types of material remains…

Image and Video Processing · Electrical Eng. & Systems 2023-11-02 Di Xu , Qihui Lyu , Dan Ruan , Ke Sheng

Most of the Deep Neural Networks (DNNs) based CT image denoising literature shows that DNNs outperform traditional iterative methods in terms of metrics such as the RMSE, the PSNR and the SSIM. In many instances, using the same metrics, the…

Computer Vision and Pattern Recognition · Computer Science 2021-11-19 Prabhat KC , Rongping Zeng , M. Mehdi Farhangi , Kyle J. Myers

Computer-aided diagnosis (CAD) based on histopathological imaging has progressed rapidly in recent years with the rise of machine learning based methodologies. Traditional approaches consist of training a classification model using features…

Computer Vision and Pattern Recognition · Computer Science 2019-03-29 Junaid Malik , Serkan Kiranyaz , Suchitra Kunhoth , Turker Ince , Somaya Al-Maadeed , Ridha Hamila , Moncef Gabbouj

Deep learning has emerged as a powerful artificial intelligence tool to interpret medical images for a growing variety of applications. However, the paucity of medical imaging data with high-quality annotations that is necessary for…

Computer Vision and Pattern Recognition · Computer Science 2018-10-02 Faisal Mahmood , Richard Chen , Sandra Sudarsky , Daphne Yu , Nicholas J. Durr