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Cancers are complex adaptive diseases regulated by the nonlinear feedback systems between genetic instabilities, environmental signals, cellular protein flows, and gene regulatory networks. Understanding the cybernetics of cancer requires…

Other Quantitative Biology · Quantitative Biology 2022-08-30 Abicumaran Uthamacumaran , Hector Zenil

Over the Eight decades, computing paradigms have shifted from large, centralized systems to compact, distributed architectures, leading to the rise of the Distributed Computing Continuum (DCC). In this model, multiple layers such as cloud,…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-10 Praveen Kumar Donta , Qiyang Zhang , Schahram Dustdar

A robust Learning Model Predictive Controller (LMPC) for uncertain systems performing iterative tasks is presented. At each iteration of the control task the closed-loop state, input and cost are stored and used in the controller design.…

Systems and Control · Electrical Eng. & Systems 2021-07-06 Ugo Rosolia , Xiaojing Zhang , Francesco Borrelli

Interactive Markov chains (IMC) are compositional behavioural models extending labelled transition systems and continuous-time Markov chains. We provide a framework and algorithms for compositional verification and optimization of IMC with…

Logic in Computer Science · Computer Science 2013-12-05 Holger Hermanns , Jan Krčál , Jan Křetínský

Hybrid interpretable models combine a transparent component with a black-box model by assigning some examples to the former and deferring the rest to the latter. While this design enables flexible tradeoffs between accuracy and…

Machine Learning · Computer Science 2026-05-28 Ziba Jabbar Zare , Ulrich Aïvodji , Julien Ferry , Thibaut Vidal

The growing gap between processor and memory speeds results in complex memory hierarchies as processors evolve to mitigate such divergence by taking advantage of the locality of reference. In this direction, the BSC performance analysis…

Performance · Computer Science 2020-06-01 Harald Servat , Jesús Labarta , Hans-Christian Hoppe , Judit Giménez , Antonio J. Peña

A general framework is presented for analyzing the stability and performance of nonlinear and linear parameter varying (LPV) time delayed systems. First, the input/output behavior of the time delay operator is bounded in the frequency…

Systems and Control · Computer Science 2015-04-13 Harald Pfifer , Peter Seiler

We provide a comprehensive review and practical implementation of a recently developed model predictive control (MPC) framework for controlling unknown systems using only measured data and no explicit model knowledge. Our approach relies on…

Systems and Control · Electrical Eng. & Systems 2022-01-03 Julian Berberich , Johannes Köhler , Matthias A. Müller , Frank Allgöwer

Predictive coding networks are neuroscience-inspired models with roots in both Bayesian statistics and neuroscience. Training such models, however, is quite inefficient and unstable. In this work, we show how by simply changing the temporal…

Neural and Evolutionary Computing · Computer Science 2024-02-08 Tommaso Salvatori , Yuhang Song , Yordan Yordanov , Beren Millidge , Zhenghua Xu , Lei Sha , Cornelius Emde , Rafal Bogacz , Thomas Lukasiewicz

We adapt tools from information theory to analyze how an observer comes to synchronize with the hidden states of a finitary, stationary stochastic process. We show that synchronization is determined by both the process's internal…

Statistical Mechanics · Physics 2015-05-19 James P. Crutchfield , Christopher J. Ellison , Ryan G. James , John R. Mahoney

Recent High-Performance Computing (HPC) systems are facing important challenges, such as massive power consumption, while at the same time significantly under-utilized system resources. Given the power consumption trends, future systems…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-05-08 Eishi Arima , Isaías A. Comprés , Martin Schulz

The computability power of a distributed computing model is determined by the communication media available to the processes, the timing assumptions about processes and communication, and the nature of failures that processes can suffer. In…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-04-27 Eric Goubault , Sergio Rajsbaum

We obtain generalizations of the Kelvin-Planck, Clausius, and Carnot statements of the second law of thermodynamics, for situations involving information processing. To this end, we consider an information reservoir (representing, e.g. a…

Statistical Mechanics · Physics 2013-10-21 Sebastian Deffner , Christopher Jarzynski

Inverse Optimal Control (IOC) seeks to recover an unknown cost from expert demonstrations, and it provides a systematic way of modeling experts' decision mechanisms while considering the prior information of the cost functions.…

Optimization and Control · Mathematics 2025-12-01 Ziliang Wang , Han Zhang , Axel Ringh

Black-box optimization is often encountered for decision-making in complex systems management, where the knowledge of system is limited. Under these circumstances, it is essential to balance the utilization of new information with…

Computation · Statistics 2025-01-15 Teng Lian , Jian-Qiang Hu , Yuhang Wu , Zeyu Zheng

This study presents a scalable data-driven algorithm designed to efficiently address the challenging problem of reachability analysis. Analysis of cyber-physical systems (CPS) relies typically on parametric physical models of dynamical…

Robotics · Computer Science 2025-05-22 Navid Hashemi , Lars Lindemann , Jyotirmoy Deshmukh

Generalized Polynomial Chaos (gPC) theory has been widely used for representing parametric uncertainty in a system, thanks to its ability to propagate uncertainty evolution. In an optimal control context, gPC can be combined with several…

Optimization and Control · Mathematics 2021-10-05 Yuichiro Aoyama , Augustinos D. Saravanos , Evangelos A. Theodorou

Information flow or information transfer is an important concept in dynamical systems which has applications in a wide variety of scientific disciplines. In this study, we show that a rigorous formalism can be established in the context of…

Chaotic Dynamics · Physics 2007-10-05 X. San Liang

Nonlinear model predictive control (MPC) is a flexible and increasingly popular framework used to synthesize feedback control strategies that can satisfy both state and control input constraints. In this framework, an optimization problem,…

Systems and Control · Electrical Eng. & Systems 2023-05-17 Kong Yao Chee , M. Ani Hsieh , Nikolai Matni

This paper proposes a form of MPC in which the control variables are moved asynchronously. This contrasts with most MIMO control schemes, which assume that all variables are updated simultaneously. MPC outperforms other control strategies…

Systems and Control · Computer Science 2015-03-17 K. V. Ling , J. M. Maciejowski , A. G. Richards , B-F. Wu
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