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Protein structure-based property prediction has emerged as a promising approach for various biological tasks, such as protein function prediction and sub-cellular location estimation. The existing methods highly rely on experimental protein…

Machine Learning · Computer Science 2023-10-20 Yufei Huang , Siyuan Li , Jin Su , Lirong Wu , Odin Zhang , Haitao Lin , Jingqi Qi , Zihan Liu , Zhangyang Gao , Yuyang Liu , Jiangbin Zheng , Stan. ZQ. Li

This paper presents a deep learning approach for the classification of Engineering (CAD) models using Convolutional Neural Networks (CNNs). Owing to the availability of large annotated datasets and also enough computational power in the…

Computer Vision and Pattern Recognition · Computer Science 2021-07-15 Bharadwaj Manda , Pranjal Bhaskare , Ramanathan Muthuganapathy

Composed of amino acid chains that influence how they fold and thus dictating their function and features, proteins are a class of macromolecules that play a central role in major biological processes and are required for the structure,…

Quantitative Methods · Quantitative Biology 2022-07-15 Aaron Wang

Object recognition has seen significant progress in the image domain, with focus primarily on 2D perception. We propose to leverage existing large-scale datasets of 3D models to understand the underlying 3D structure of objects seen in an…

Computer Vision and Pattern Recognition · Computer Science 2020-07-28 Weicheng Kuo , Anelia Angelova , Tsung-Yi Lin , Angela Dai

We propose a novel 3D face recognition algorithm using a deep convolutional neural network (DCNN) and a 3D augmentation technique. The performance of 2D face recognition algorithms has significantly increased by leveraging the…

Computer Vision and Pattern Recognition · Computer Science 2017-04-03 Donghyun Kim , Matthias Hernandez , Jongmoo Choi , Gerard Medioni

3D data is a valuable asset the computer vision filed as it provides rich information about the full geometry of sensed objects and scenes. Recently, with the availability of both large 3D datasets and computational power, it is today…

Computer Vision and Pattern Recognition · Computer Science 2019-04-09 Eman Ahmed , Alexandre Saint , Abd El Rahman Shabayek , Kseniya Cherenkova , Rig Das , Gleb Gusev , Djamila Aouada , Bjorn Ottersten

Proteins are central to biological systems, participating as building blocks across all forms of life. Despite advancements in understanding protein functions through protein sequence analysis, there remains potential for further…

Machine Learning · Computer Science 2025-08-29 Yunqing Liu , Wenqi Fan , Xiaoyong Wei , Qing Li

Recent advancements in deep learning for predicting 3D protein structures have shown promise, particularly when leveraging inputs like protein sequences and Cryo-Electron microscopy (Cryo-EM) images. However, these techniques often fall…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Jaydeep Rade , Ethan Herron , Soumik Sarkar , Anwesha Sarkar , Adarsh Krishnamurthy

Understanding the dynamic nature of protein structures is essential for comprehending their biological functions. While significant progress has been made in predicting static folded structures, modeling protein motions on microsecond to…

We investigate the problem of learning to generate 3D parametric surface representations for novel object instances, as seen from one or more views. Previous work on learning shape reconstruction from multiple views uses discrete…

Computer Vision and Pattern Recognition · Computer Science 2020-08-19 Jiahui Lei , Srinath Sridhar , Paul Guerrero , Minhyuk Sung , Niloy Mitra , Leonidas J. Guibas

Motivation: Drug discovery demands rapid quantification of compound-protein interaction (CPI). However, there is a lack of methods that can predict compound-protein affinity from sequences alone with high applicability, accuracy, and…

Biomolecules · Quantitative Biology 2020-12-17 Mostafa Karimi , Di Wu , Zhangyang Wang , Yang Shen

The inapplicability of amino acid covariation methods to small protein families has limited their use for structural annotation of whole genomes. Recently, deep learning has shown promise in allowing accurate residue-residue contact…

Biomolecules · Quantitative Biology 2019-09-10 Joe G Greener , Shaun M Kandathil , David T Jones

Understanding protein structure-function relationships is a key challenge in computational biology, with applications across the biotechnology and pharmaceutical industries. While it is known that protein structure directly impacts protein…

Biomolecules · Quantitative Biology 2020-11-02 Nicolas Swenson , Aditi S. Krishnapriyan , Aydin Buluc , Dmitriy Morozov , Katherine Yelick

Proteins perform essential biological functions, and accurate classification of their sequences is critical for understanding structure-function relationships, enzyme mechanisms, and molecular interactions. This study presents a deep…

Quantitative Methods · Quantitative Biology 2025-11-19 Pratik Chakraborty , Aryan Bhargava

Achieving robust multi-person 2D body landmark localization and pose estimation is essential for human behavior and interaction understanding as encountered for instance in HRI settings. Accurate methods have been proposed recently, but…

Computer Vision and Pattern Recognition · Computer Science 2019-12-03 Angel Martínez-González , Michael Villamizar , Olivier Canévet , Jean-Marc Odobez

Recently, machine learning (ML) has established itself in various worldwide benchmarking competitions in computational biology, including Critical Assessment of Structure Prediction (CASP) and Drug Design Data Resource (D3R) Grand…

Biomolecules · Quantitative Biology 2020-04-22 Duc D Nguyen , Zixuan Cang , Guo-Wei Wei

Visual scenes are composed of visual concepts and have the property of combinatorial explosion. An important reason for humans to efficiently learn from diverse visual scenes is the ability of compositional perception, and it is desirable…

Machine Learning · Computer Science 2023-06-16 Jinyang Yuan , Tonglin Chen , Bin Li , Xiangyang Xue

Most 3D neural networks are trained from scratch owing to the lack of large-scale labeled 3D datasets. In this paper, we present a novel 3D pretraining method by leveraging 2D networks learned from rich 2D datasets. We propose the…

Computer Vision and Pattern Recognition · Computer Science 2021-12-28 Yueh-Cheng Liu , Yu-Kai Huang , Hung-Yueh Chiang , Hung-Ting Su , Zhe-Yu Liu , Chin-Tang Chen , Ching-Yu Tseng , Winston H. Hsu

High-resolution representations are essential for position-sensitive vision problems, such as human pose estimation, semantic segmentation, and object detection. Existing state-of-the-art frameworks first encode the input image as a…

Computer Vision and Pattern Recognition · Computer Science 2020-03-16 Jingdong Wang , Ke Sun , Tianheng Cheng , Borui Jiang , Chaorui Deng , Yang Zhao , Dong Liu , Yadong Mu , Mingkui Tan , Xinggang Wang , Wenyu Liu , Bin Xiao

When interacting in a three dimensional world, humans must estimate 3D structure from visual inputs projected down to two dimensional retinal images. It has been shown that humans use the persistence of object shape over motion-induced…

Neurons and Cognition · Quantitative Biology 2023-04-03 Marissa Connor , Bruno Olshausen , Christopher Rozell