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Motivation: Modelling methods that find structure in data are necessary with the current large volumes of genomic data, and there have been various efforts to find subsets of genes exhibiting consistent patterns over subsets of treatments.…

Machine Learning · Computer Science 2016-09-15 Kerstin Bunte , Eemeli Leppäaho , Inka Saarinen , Samuel Kaski

Matrix factorization is a key tool in data analysis; its applications include recommender systems, correlation analysis, signal processing, among others. Binary matrices are a particular case which has received significant attention for…

Machine Learning · Statistics 2019-01-30 Ignacio Ramirez

Unsupervised integrative analysis of multiple data sources has become common place and scalable algorithms are necessary to accommodate ever increasing availability of data. Only few currently methods have estimation speed as their focus,…

Methodology · Statistics 2024-05-17 Felix Held

Boolean matrix factorization (BMF) has many applications in data mining, bioinformatics, and network analysis. The goal of BMF is to decompose a given binary matrix as the Boolean product of two smaller binary matrices, revealing underlying…

Commutative Algebra · Mathematics 2025-09-12 Juliann Geraci , Alexander B. Kunin , Alexandra Seceleanu

Identifying altered pathways that are associated with specific cancer types can potentially bring a significant impact on cancer patient treatment. Accurate identification of such key altered pathways information can be used to develop…

Machine Learning · Statistics 2017-12-05 Sunho Park , Tae Hyun Hwang

With the increasing availability of various sensor technologies, we now have access to large amounts of multi-block (also called multi-set, multi-relational, or multi-view) data that need to be jointly analyzed to explore their latent…

Computational Engineering, Finance, and Science · Computer Science 2015-09-01 Guoxu Zhou , Qibin Zhao , Yu Zhang , Tülay Adalı , Shengli Xie , Andrzej Cichocki

Rapid technological advances have allowed for molecular profiling across multiple omics domains from a single sample for clinical decision making in many diseases, especially cancer. As tumor development and progression are dynamic…

Methodology · Statistics 2022-02-11 Dongyan Yan , Subharup Guha

Boolean matrix factorisation aims to decompose a binary data matrix into an approximate Boolean product of two low rank, binary matrices: one containing meaningful patterns, the other quantifying how the observations can be expressed as a…

Machine Learning · Statistics 2017-02-28 Tammo Rukat , Chris C. Holmes , Michalis K. Titsias , Christopher Yau

Factorization Machines (FM), a general predictor that can efficiently model feature interactions in linear time, was primarily proposed for collaborative recommendation and have been broadly used for regression, classification and ranking…

Machine Learning · Computer Science 2021-08-18 Yu Geng , Liang Lan

Matrix factorization is a very common machine learning technique in recommender systems. Bayesian Matrix Factorization (BMF) algorithms would be attractive because of their ability to quantify uncertainty in their predictions and avoid…

Machine Learning · Computer Science 2020-04-15 Tom Vander Aa , Xiangju Qin , Paul Blomstedt , Roel Wuyts , Wilfried Verachtert , Samuel Kaski

Matrix factorization is a fundamental method in statistics and machine learning for inferring and summarizing structure in multivariate data. Modern data sets often come with "side information" of various forms (images, text, graphs) that…

Pan-omics, pan-cancer analysis has advanced our understanding of the molecular heterogeneity of cancer, expanding what was known from single-cancer or single-omics studies. However, pan-cancer, pan-omics analyses have been limited in their…

Applications · Statistics 2021-03-02 Sarah Samorodnitsky , Katherine A. Hoadley , Eric F. Lock

Identifying discrete patterns in binary data is an important dimensionality reduction tool in machine learning and data mining. In this paper, we consider the problem of low-rank binary matrix factorisation (BMF) under Boolean arithmetic.…

Optimization and Control · Mathematics 2021-08-05 Reka A. Kovacs , Oktay Gunluk , Raphael A. Hauser

Rapid advancements in collection and dissemination of multi-platform molecular and genomics data has resulted in enormous opportunities to aggregate such data in order to understand, prevent, and treat human diseases. While significant…

In this paper, we propose a distributed framework for reducing the dimensionality of high-dimensional, large-scale, heterogeneous matrix-variate time series data using a factor model. The data are first partitioned column-wise (or row-wise)…

Machine Learning · Statistics 2026-01-19 Hangjin Jiang , Yuzhou Li , Zhaoxing Gao

Over the past few years, there has been a considerable spread of microarray technology in many biological patterns, particularly in those pertaining to cancer diseases like leukemia, prostate, colon cancer, etc. The primary bottleneck that…

Quantitative Methods · Quantitative Biology 2020-07-20 Parth Patel , Kalpdrum Passi , Chakresh Kumar Jain

Factor Analysis based on multivariate $t$ distribution ($t$fa) is a useful robust tool for extracting common factors on heavy-tailed or contaminated data. However, $t$fa is only applicable to vector data. When $t$fa is applied to matrix…

Machine Learning · Statistics 2024-01-05 Xuan Ma , Jianhua Zhao , Changchun Shang , Fen Jiang , Philip L. H. Yu

We extend kernelized matrix factorization with a fully Bayesian treatment and with an ability to work with multiple side information sources expressed as different kernels. Kernel functions have been introduced to matrix factorization to…

Machine Learning · Statistics 2013-05-10 Mehmet Gönen , Suleiman A. Khan , Samuel Kaski

Data integration methods that analyze multiple sources of data simultaneously can often provide more holistic insights than can separate inquiries of each data source. Motivated by the advantages of data integration in the era of "big…

Methodology · Statistics 2020-01-13 Yulia Baker , Tiffany M. Tang , Genevera I. Allen

Low-dimensional embeddings for data from disparate sources play critical roles in multi-modal machine learning, multimedia information retrieval, and bioinformatics. In this paper, we propose a supervised dimensionality reduction method…

Machine Learning · Computer Science 2021-01-15 Yanjun Li , Bihan Wen , Hao Cheng , Yoram Bresler