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Can we understand and predict the evolutionary pathways by which bacteria acquire multi-drug resistance (MDR)? These questions have substantial potential impact in basic biology and in applied approaches to address the global health…

Populations and Evolution · Quantitative Biology 2024-11-05 Jessica Renz , Kazeem A. Dauda , Olav N. L. Aga , Ramon Diaz-Uriarte , Iren H. Löhr , Bjørn Blomberg , Iain G. Johnston

Active learning has shown to reduce the number of experiments needed to obtain high-confidence drug-target predictions. However, in order to actually save experiments using active learning, it is crucial to have a method to evaluate the…

Quantitative Methods · Quantitative Biology 2015-04-10 Maja Temerinac-Ott , Armaghan W. Naik , Robert F. Murphy

A huge amount of medical data is generated every day, which presents a challenge in analysing these data. The obvious solution to this challenge is to reduce the amount of data without information loss. Dimension reduction is considered the…

Computers and Society · Computer Science 2015-11-24 Noura AlNuaimi , Mohammad M Masud , Farhan Mohammed

This work discloses an epidemiological mathematical model to predict an empirical treatment for dogs infected by Pseudomonas aeruginosa. This dangerous pathogen is one of the leading causes of multi-resistant infections and can be…

Populations and Evolution · Quantitative Biology 2024-01-17 Javier López-de-la-Cruz , María Pérez-Aranda , Ana Alcudia , Belén Begines , Tomás Caraballo , Eloísa Pajuelo , Pedro J. Ginel

While kidney transplants are seen as the best treatment option for patients with end-stage renal disease and kidney failure, the organ's health depends on the dosage of immunosuppressant drugs post-transplantation. Due to the dosage…

Quantitative Methods · Quantitative Biology 2023-09-19 Kapil Panda , Anirudh Mazumder

Motivation: Many researchers with domain expertise are unable to easily apply machine learning to their bioinformatics data due to a lack of machine learning and/or coding expertise. Methods that have been proposed thus far to automate…

Machine Learning · Computer Science 2020-04-29 William La Cava , Heather Williams , Weixuan Fu , Steve Vitale , Durga Srivatsan , Jason H. Moore

In many machine learning applications, there are multiple decision-makers involved, both automated and human. The interaction between these agents often goes unaddressed in algorithmic development. In this work, we explore a simple version…

Machine Learning · Statistics 2018-09-10 David Madras , Toniann Pitassi , Richard Zemel

Algorithms are increasingly common components of high-impact decision-making, and a growing body of literature on adversarial examples in laboratory settings indicates that standard machine learning models are not robust. This suggests that…

Machine Learning · Statistics 2018-11-28 Suproteem K. Sarkar , Kojin Oshiba , Daniel Giebisch , Yaron Singer

Machine learning is a powerful tool for predicting human-related outcomes, from credit scores to heart attack risks. But when deployed, learned models also affect how users act in order to improve outcomes, whether predicted or real. The…

Machine Learning · Computer Science 2020-06-24 Nir Rosenfeld , Sophie Hilgard , Sai Srivatsa Ravindranath , David C. Parkes

The development of an intelligent agricultural decision-supporting system for crop selection and disease forecasting in Bangladesh is the main objective of this work. The economy of the nation depends heavily on agriculture. However,…

Machine Learning · Computer Science 2024-03-29 Forkan Uddin Ahmed , Annesha Das , Md Zubair

Digital systems find it challenging to keep up with cybersecurity threats. The daily emergence of more than 560,000 new malware strains poses significant hazards to the digital ecosystem. The traditional malware detection methods fail to…

Cryptography and Security · Computer Science 2025-04-28 Abrar Fahim , Shamik Dey , Md. Nurul Absur , Md Kamrul Siam , Md. Tahmidul Huque , Jafreen Jafor Godhuli

Purpose: Subarachnoid haemorrhage is a potentially fatal consequence of intracranial aneurysm rupture, however, it is difficult to predict if aneurysms will rupture. Prophylactic treatment of an intracranial aneurysm also involves risk,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-09 Karan Daga , Siddharth Agarwal , Zaeem Moti , Matthew BK Lee , Munaib Din , David Wood , Marc Modat , Thomas C Booth

Motivation: HIV is difficult to treat because its virus mutates at a high rate and mutated viruses easily develop resistance to existing drugs. If the relationships between mutations and drug resistances can be determined from historical…

Quantitative Methods · Quantitative Biology 2019-07-08 Li Xing , Mary Lesperance , Xuekui Zhang

Progression to dialysis or end-stage renal disease is a rare but clinically important outcome. Clinicians need evidence on how medication exposures influence downstream risk. We constructed a fixed-window EHR cohort (90-day observation,…

Machine Learning · Computer Science 2026-04-28 Kalyani P. Pande , Evan Yang , Bryan Zhu , Sandeep K. Mallipattu , Alisa Yurovsky , Tengfei Ma

Understanding performance and prioritizing resources for the maintenance of the drinking-water pipe network throughout its life-cycle is a key part of water asset management. Renovation of this vital network is generally hindered by the…

Signal Processing · Electrical Eng. & Systems 2020-07-09 Maryam Rahbaralam , David Modesto , Jaume Cardús , Amir Abdollahi , Fernando M Cucchietti

The global need for effective disease diagnosis remains substantial, given the complexities of various disease mechanisms and diverse patient symptoms. To tackle these challenges, researchers, physicians, and patients are turning to machine…

Machine Learning · Computer Science 2023-10-27 S M Atikur Rahman , Sifat Ibtisum , Ehsan Bazgir , Tumpa Barai

ICU readmission is associated with longer hospitalization, mortality and adverse outcomes. An early recognition of ICU re-admission can help prevent patients from worse situation and lower treatment cost. As the abundance of Electronics…

Machine Learning · Computer Science 2019-10-08 Zhiheng Li , Xinyue Xing , Bingzhang Lu , Zhixiang Li

Drug resistance is a major threat to the global health and a significant concern throughout the clinical treatment of diseases and drug development. The mutation in proteins that is related to drug binding is a common cause for adaptive…

Quantitative Methods · Quantitative Biology 2022-05-18 Ziyi Yang , Zhaofeng Ye , Yijia Xiao , Changyu Hsieh , Shengyu Zhang

This paper shows how data science can contribute to improving empirical research in economics by leveraging on large datasets and extracting information otherwise unsuitable for a traditional econometric approach. As a test-bed for our…

General Economics · Economics 2019-11-05 Marco Guerzoni , Consuelo R. Nava , Massimiliano Nuccio

Machine learning has become one of the main components for task automation in many application domains. Despite the advancements and impressive achievements of machine learning, it has been shown that learning algorithms can be compromised…

Cryptography and Security · Computer Science 2018-08-20 Ziyi Bao , Luis Muñoz-González , Emil C. Lupu
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