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The Bayesian evidence, crucial ingredient for model selection, is arguably the most important quantity in Bayesian data analysis: at the same time, however, it is also one of the most difficult to compute. In this paper we present a…

Methodology · Statistics 2024-05-14 Stefano Rinaldi , Gabriele Demasi , Walter Del Pozzo , Otto A. Hannuksela

Myocardial perfusion imaging using SPECT is widely utilized to diagnose coronary artery diseases, but image quality can be negatively affected in low-dose and few-view acquisition settings. Although various deep learning methods have been…

Bayesian inference is an effective approach for solving statistical learning problems especially with uncertainty and incompleteness. However, inference efficiencies are physically limited by the bottlenecks of conventional computing…

Emerging Technologies · Computer Science 2017-11-06 Xiaotao Jia , Jianlei Yang , Zhaohao Wang , Yiran Chen , Hai , Li , Weisheng Zhao

Spatial functional data arise in many settings, such as particulate matter curves observed at monitoring stations and age population curves at each areal unit. Most existing functional regression models have limited applicability because…

Methodology · Statistics 2025-04-25 Heesang Lee , Dagun Oh , Sunhwa Choi , Jaewoo Park

In recent years, disease mapping studies have become a routine application within geographical epidemiology and are typically analysed within a Bayesian hierarchical model formulation. A variety of model formulations for the latent level…

Methodology · Statistics 2016-01-07 Andrea Riebler , Sigrunn H. Sørbye , Daniel Simpson , Håvard Rue

Variational inference provides approximations to the computationally intractable posterior distribution in Bayesian networks. A prominent medical application of noisy-or Bayesian network is to infer potential diseases given observed…

Machine Learning · Computer Science 2016-05-23 Yusheng Xie , Nan Du , Wei Fan , Jing Zhai , Weicheng Zhu

Usually one compares the accuracy of two competing classifiers via null hypothesis significance tests (nhst). Yet the nhst tests suffer from important shortcomings, which can be overcome by switching to Bayesian hypothesis testing. We…

Machine Learning · Computer Science 2016-11-23 Giorgio Corani , Alessio Benavoli , Janez Demšar , Francesca Mangili , Marco Zaffalon

Bayesian inference typically requires the computation of an approximation to the posterior distribution. An important requirement for an approximate Bayesian inference algorithm is to output high-accuracy posterior mean and uncertainty…

Statistics Theory · Mathematics 2018-10-03 Jonathan H. Huggins , Trevor Campbell , Mikołaj Kasprzak , Tamara Broderick

The validity of two-step or plug-in inference methods is questioned in the Bayesian framework. We study semi-parametric models where the plug-in of a non-parametrically modelled nuisance component is used. We show that when the nuisance and…

Statistics Theory · Mathematics 2026-02-25 Magid Sabbagh , David A. Stephens

The performance of error correction in the surface code can be enhanced by leveraging the knowledge of the noise model for physical qubits. To provide accurate noise information to the decoder in parallel with quantum computation, an…

Quantum Physics · Physics 2025-12-04 Takumi Kobori , Synge Todo

Microstructural models of soft tissue deformation are important in applications including artificial tissue design and surgical planning. The basis of these models, and their advantage over their phenomenological counterparts, is that they…

Biological Physics · Physics 2022-05-06 James Haughton , Simon L. Cotter , William J. Parnell , Tom Shearer

Myocardial perfusion imaging (MPI) with single-photon emission computed tomography (SPECT) is a widely used and cost-effective diagnostic tool for coronary artery disease. However, the lengthy scanning time in this imaging procedure can…

Computer Vision and Pattern Recognition · Computer Science 2025-04-24 Zezhang Yang , Zitong Yu , Nuri Choi , Abhinav K. Jha

Mathematical models support inference and forecasting in ecology and epidemiology, but results depend on the estimation framework. We compare Bayesian and Frequentist approaches across three biological models using four datasets:…

Quantitative Methods · Quantitative Biology 2026-03-31 Mohammed A. Y. Mohammed , Hamed Karami , Gerardo Chowell

Structural equation models are commonly used to capture the relationship between sets of observed and unobservable variables. Traditionally these models are fitted using frequentist approaches but recently researchers and practitioners have…

Methodology · Statistics 2023-02-22 Khue-Dung Dang , Luca Maestrini

Bayesian inference, while foundational to probabilistic reasoning, is often hampered by the computational intractability of posterior distributions, particularly through the challenging evidence integral. Conventional approaches like Markov…

Machine Learning · Computer Science 2025-11-11 Di Zhang

The advances of next-generation sequencing technology have accelerated study of the microbiome and stimulated the high throughput profiling of metagenomes. The large volume of sequenced data has encouraged the rise of various studies for…

Methodology · Statistics 2019-04-30 Qiwei Li , Shuang Jiang , Andrew Y. Koh , Guanghua Xiao , Xiaowei Zhan

High-dimensional vector autoregression with measurement error is frequently encountered in a large variety of scientific and business applications. In this article, we study statistical inference of the transition matrix under this model.…

Methodology · Statistics 2020-09-18 Xiang Lyu , Jian Kang , Lexin Li

We develop a computational framework to quantify uncertainty in shear elastography imaging of anomalies in tissues. We adopt a Bayesian inference formulation. Given the observed data, a forward model and their uncertainties, we find the…

Numerical Analysis · Mathematics 2023-06-07 Ana Carpio , Elena Cebrian , Andrea Gutierrez

Positron emission tomography (PET) enables quantification of dynamic physiological processes through time-resolved imaging. In Rb-82 myocardial perfusion PET, kinetic compartment modeling is used to estimate physiological parameters and…

Medical Physics · Physics 2026-04-09 Myungheon Chin , Sarah J Zou , Garry Chinn , Craig S. Levin

A fast and general Bayesian inference framework to infer the physical properties of dichroic polarization using mid-infrared imaging- and spectro-polarimetric observations is presented. The Bayesian approach is based on a hierarchical…

Instrumentation and Methods for Astrophysics · Physics 2015-12-02 E. Lopez-Rodriguez
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