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Molecular dynamics (MD) simulations provide detailed insight into atomic-scale mechanisms but are inherently restricted to small spatio-temporal scales. Coarse-grained molecular dynamics (CGMD) techniques allow simulations of much larger…

Computational Physics · Physics 2025-02-10 Yangshuai Wang , Gabor Csanyi , Christoph Ortner

Coarse-grained (CG) models can provide computationally efficient and conceptually simple characterizations of soft matter systems. While generic models probe the underlying physics governing an entire family of free-energy landscapes,…

Soft Condensed Matter · Physics 2019-08-15 Joseph F. Rudzinski

A generalized understanding of protein dynamics is an unsolved scientific problem, the solution of which is critical to the interpretation of the structure-function relationships that govern essential biological processes. Here, we approach…

We present a multiscale simulation of liquid water where a spatially adaptive molecular resolution procedure allows for changing on-the-fly from a coarse-grained to an all-atom representation. We show that this approach leads to the correct…

Soft Condensed Matter · Physics 2007-07-09 Matej Praprotnik , Luigi Delle Site , Kurt Kremer , Silvina Matysiak , Cecilia Clementi

This study presents a coarse-grained molecular dynamics simulation model to investigate the process of oxidative aging in polymers. The chemical aging effect is attributed to the auto-oxidation mechanism, which is initiated by radicals,…

Soft Condensed Matter · Physics 2023-11-28 Takato Ishida , Yuya Doi , Takashi Uneyama , Yuichi Masubuchi

We consider a coarse-grained (CG) model with pairwise interactions, suitable to describe low-density solutions of star-branched polymers of functionality $f$. Each macromolecule is represented by a CG molecule with $(f+1)$ interaction…

Soft Condensed Matter · Physics 2017-08-02 Roberto Menichetti , Andrea Pelissetto , Ferdinando Randisi

The fully atomistic modeling of real-size plasmonic nanostructures is computationally demanding, therefore most calculations are limited to small-to-medium sized systems. However, plasmonic properties strongly depend on the actual shape and…

Computational Physics · Physics 2022-09-13 Piero Lafiosca , Tommaso Giovannini , Michele Benzi , Chiara Cappelli

For the study of complex synthetic and biological molecular systems by computer simulations one is still restricted to simple model systems or to by far too small time scales. To overcome this problem multiscale techniques are being…

Statistical Mechanics · Physics 2007-05-23 Matej Praprotnik , Kurt Kremer , Luigi Delle Site

Polymer-grafted nanoparticles are versatile building blocks that self-assemble into a rich diversity of mesostructures. Coarse-grained molecular simulations have commonly accompanied experiments by resolving structure formation pathways and…

Soft Condensed Matter · Physics 2025-09-30 Federico Tomazic , Aswathy Muttathukattil , Afshin Nabiyan , Felix Schacher , Michael Engel

Molecular dynamics simulations provide theoretical insight into the microscopic behavior of materials in condensed phase and, as a predictive tool, enable computational design of new compounds. However, because of the large temporal and…

Chemical Physics · Physics 2020-06-18 Wujie Wang , Rafael Gómez-Bombarelli

We present a general approach to isolate chemical reaction mechanism as an independently controllable variable across chemically distinct systems. Modern approaches to reduce the computational expense of molecular dynamics simulations often…

Simplified representations of macromolecules help in rationalising and understanding the outcome of atomistic simulations, and serve to the construction of effective, coarse-grained models. The number and distribution of coarse-grained…

Soft Condensed Matter · Physics 2021-10-27 Roberto Menichetti , Marco Giulini , Raffaello Potestio

A coupled hygro-thermo-mechanical computational model is proposed for fibre reinforced polymers, formulated within the framework of Computational Homogenisation (CH). At each macrostructure Gauss point, constitutive matrices for thermal,…

Computational Engineering, Finance, and Science · Computer Science 2016-10-14 Zahur Ullah , Lukasz Kaczmarczyk , Sotirios Grammatikos , Mark Evernden , Chris Pearce

Soft condensed matter structures often challenge us with complex many-body phenomena governed by collective modes spanning wide spatial and temporal domains. In order to successfully tackle such problems mesoscopic coarse-grained (CG)…

Soft Condensed Matter · Physics 2023-07-12 Vlad P Sokhan , Michael A Seaton , Ilian T Todorov

Mesogens, which are typically stiff rodlike or disklike molecules, are able to self-organize into liquid crystal (LC) phases in a certain temperature range. Such mesogens, or LC groups, can be attached to polymer chains in various…

Soft Condensed Matter · Physics 2023-06-21 Diego Becerra , Pranav R. Jois , Lisa M. Hall

A mixture of solvent particles with short-range, directional interactions and solute particles with short-range, isotropic interactions that can bond multiple times is of fundamental interest in understanding liquids and colloidal mixtures.…

Soft Condensed Matter · Physics 2016-09-21 Artee Bansal , D. Asthagiri , Kenneth R. Cox , Walter G. Chapman

The present research is dedicated to provide deeper understanding of the impact of complex architecture of branched polymers on their behaviour in solvents. The folding dynamics of macromolecules and hydrodynamics of polymer fluids are…

Soft Condensed Matter · Physics 2020-12-09 K. Haydukivska , V. Blavatska , J. Paturej

Dynamical polydispersity in single-particle properties, for example a fluctuating particle size, shape, charge density, etc., is intrinsic to responsive colloids (RCs), such as biomacromolecules or microgels, but is typically not resolved…

Soft Condensed Matter · Physics 2021-05-26 Upayan Baul , Joachim Dzubiella

During the melting transition of dimyristoyl phosphatidylglycerol (DMPG), the order of the lipid chains and the three-dimensional, vesicular structural arrangement change simultaneously. These changes result in peculiar heat capacity…

Biological Physics · Physics 2025-09-29 Thomas Heimburg , Holger Ebel , Peter Grabitz , Julia Preu , Yue Wang

We introduce a framework for model reduction of chain models for dissipative particle dynamics (DPD) simulations, where the characteristic size of the chain, pressure, density, and temperature are preserved. The proposed methodology reduces…

Soft Condensed Matter · Physics 2016-05-04 Nicolas Moreno , Suzana P. Nunes , Victor M. Calo
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