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Optical-resolution fluorescence imaging through and within complex samples presents a significant challenge due to random light scattering, with substantial implications across multiple fields. While significant advancements in coherent…

Optics · Physics 2023-12-27 Gil Weinberg , Elad Sunray , Ori Katz

Optical imaging through scattering media is a long-standing challenge. Although many approaches have been developed to focus light or image objects through scattering media, they are either invasive, restricted to stationary or…

Optics · Physics 2022-10-11 Xingchen Zhao , Xiaoyu Nie , Zhenhuan Yi , Tao Peng , Marlan O. Scully

Random scattering of light in disordered media is an intriguing phenomenon of fundamental relevance to various applications. While techniques such as wavefront shaping and transmission matrix measurements have enabled remarkable progress…

Imaging through scattering is a pervasive and difficult problem in many biological applications. The high background and the exponentially attenuated target signals due to scattering fundamentally limits the imaging depth of fluorescence…

Signal Processing · Electrical Eng. & Systems 2023-12-11 Jeffrey Alido , Joseph Greene , Yujia Xue , Guorong Hu , Yunzhe Li , Mitchell Gilmore , Kevin J. Monk , Brett T. DiBenedictis , Ian G. Davison , Lei Tian

Full-field imaging through scattering media is fraught with many challenges. Despite many achievements in recent years, current imaging methods are too slow to deal with fast dynamics that occur for example in biomedical imaging. Here we…

Angular speckle correlations known as the 'memory-effect' have recently been exploited for non-invasive imaging through scattering layers. Here, we show how the imaging information obtained from speckle correlations can be used as a…

Optics · Physics 2019-01-30 Galya Stern , Ori Katz

We study active array imaging of small but strong scatterers in homogeneous media when multiple scattering between them is important. We use the Foldy-Lax equations to model wave propagation with multiple scattering when the scatterers are…

Mathematical Physics · Physics 2015-12-15 Anwei Chai , Miguel Moscoso , George Papanicolaou

Optical approaches to fluorescent, spectroscopic, and morphological imaging have made exceptional advances in the last decade. Super-resolution imaging and wide-field multiphoton imaging are now underpinning major advances across the…

Optimization approaches are ubiquitous in physics. In optics, they are key to manipulating light through complex media, enabling applications ranging from imaging to photonic simulators. In most demonstrations, however, the optimization…

Quantum Physics · Physics 2025-08-28 Baptiste Courme , Chloé Vernière , Malo Joly , Daniele Faccio , Sylvain Gigan , Hugo Defienne

Light passing through scattering media will be strongly scattered and diffused into complex speckle pattern, which contains almost all the spatial information and spectral information of the objects. Although various methods have been…

Optics · Physics 2019-02-04 Lei Zhu , Jietao Liu , Lei Feng , Chengfei Guo , Tengfei Wu , Xiaopeng Shao

Scattering, especially multiple scattering, is a well known problem in imaging, ranging from astronomy to medicine. In particular it is often desirable to be able to perform non-invasive imaging through turbid and/or opaque media. Many…

Optics · Physics 2024-04-23 Harry Penketh , Jacopo Bertolotti

This work is concerned with optical imaging in strongly diffusive environments. We consider a typical setting in optical coherence tomography where a sample is probed by a collection of wavefields produced by a laser and propagating through…

Optics · Physics 2024-12-10 Randy Bartels , Olivier Pinaud , Maxine Varughese

As light travels through a disordered medium such as biological tissues, it undergoes multiple scattering events. This phenomenon is detrimental to in-depth optical microscopy, as it causes a drastic degradation of contrast, resolution and…

There are several methods to focus light behind a scattering medium, but very few use fluorescence light as feedback or can be used without access to the distal side of the scatterer. Among all the wave-front shaping techniques, retrieving…

Optics · Physics 2020-03-18 Evolene Premillieu , Rafael Piestun

The purpose of this paper is to investigate the scattering by a nonlinear crystal whose depth is about the wavelength of the impinging field. More precisely, an infinite nonlinear slab is illuminated by an incident field which is the sum of…

Optics · Physics 2010-11-22 Pierre Godard , Frederic Zolla , Andre Nicolet

Light propagation in materials with microscopic inhomogeneities is affected by scattering. In scattering materials, such as powders, disordered metamaterials or biological tissue, multiple scattering on sub-wavelength particles makes light…

Disordered Systems and Neural Networks · Physics 2009-11-13 I. M. Vellekoop , A. P. Mosk

Light scattering in inhomogeneous media induces wavefront distortions which pose an inherent limitation in many optical applications. Examples range from microscopy and nanosurgery to astronomy. In recent years, ongoing efforts have made…

Optics · Physics 2015-05-20 Ori Katz , Yaron Bromberg , Eran Small , Yaron Silberberg

Imaging through scattering is an important, yet challenging problem. Tremendous progress has been made by exploiting the deterministic input-output "transmission matrix" for a fixed medium. However, this "one-to-one" mapping is highly…

Image and Video Processing · Electrical Eng. & Systems 2018-09-27 Yunzhe Li , Yujia Xue , Lei Tian

In turbid media, scattering of light scrambles information of the incident beam and represents an obstacle to optical imaging. Noninvasive imaging through opaque layers is challenging for dynamic and wide-field objects due to unreliable…

Optics · Physics 2018-10-17 Yuan Yuan , Hui Chen

This thesis describes experimental work on the use of wavefront shaping to steer light through strongly scattering materials. We find that scattering does not irreversibly scramble the incident wave. By shaping the incident wavefront, we…

Optics · Physics 2008-07-08 I. M. Vellekoop