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Clinical decisions are high-stakes and require explicit justification, making model interpretability essential for auditing deep clinical models prior to deployment. As the ecosystem of model architectures and explainability methods…

Machine Learning · Computer Science 2026-03-27 Yongda Fan , John Wu , Andrea Fitzpatrick , Naveen Baskaran , Jimeng Sun , Adam Cross

Methods for interpreting machine learning black-box models increase the outcomes' transparency and in turn generates insight into the reliability and fairness of the algorithms. However, the interpretations themselves could contain…

Machine Learning · Computer Science 2019-06-05 Yujia Zhang , Kuangyan Song , Yiming Sun , Sarah Tan , Madeleine Udell

Building generalizable AI models is one of the primary challenges in the healthcare domain. While radiologists rely on generalizable descriptive rules of abnormality, Neural Network (NN) models suffer even with a slight shift in input…

Computer Vision and Pattern Recognition · Computer Science 2023-07-12 Shantanu Ghosh , Ke Yu , Kayhan Batmanghelich

The impressive capabilities of deep learning models are often counterbalanced by their inherent opacity, commonly termed the "black box" problem, which impedes their widespread acceptance in high-trust domains. In response, the intersecting…

Machine Learning · Computer Science 2025-09-16 Mitali Raj

As machine learning becomes an important part of many real world applications affecting human lives, new requirements, besides high predictive accuracy, become important. One important requirement is transparency, which has been associated…

Machine Learning · Computer Science 2019-08-01 Tiago Botari , Rafael Izbicki , Andre C. P. L. F. de Carvalho

Trustworthy machine learning is driving a large number of ML community works in order to improve ML acceptance and adoption. The main aspect of trustworthy machine learning are the followings: fairness, uncertainty, robustness,…

Machine Learning · Computer Science 2022-07-08 Gregory Scafarto , Nicolas Posocco , Antoine Bonnefoy

The ubiquity of machine learning based predictive models in modern society naturally leads people to ask how trustworthy those models are? In predictive modeling, it is quite common to induce a trade-off between accuracy and…

Machine Learning · Computer Science 2019-04-05 John Mitros , Brian Mac Namee

For optimization models to be used in practice, it is crucial that users trust the results. A key factor in this aspect is the interpretability of the solution process. A previous framework for inherently interpretable optimization models…

Optimization and Control · Mathematics 2026-02-13 Marc Goerigk , Michael Hartisch , Sebastian Merten , Kartikey Sharma

Machine learning is permeating every conceivable domain to promote data-driven decision support. The focus is often on advanced black-box models due to their assumed performance advantages, whereas interpretable models are often associated…

Machine Learning · Computer Science 2024-09-24 Sven Kruschel , Nico Hambauer , Sven Weinzierl , Sandra Zilker , Mathias Kraus , Patrick Zschech

The interpretability of model has become one of the obstacles to its wide application in the high-stake fields. The usual way to obtain interpretability is to build a black-box first and then explain it using the post-hoc methods. However,…

Machine Learning · Computer Science 2023-04-04 Zihao Chen , Xiaomeng Wang , Yuanjiang Huang , Tao Jia

There is a need of ensuring machine learning models that are interpretable. Higher interpretability of the model means easier comprehension and explanation of future predictions for end-users. Further, interpretable machine learning models…

Machine Learning · Computer Science 2020-08-17 Gregor Stiglic , Primoz Kocbek , Nino Fijacko , Marinka Zitnik , Katrien Verbert , Leona Cilar

As machine learning systems are increasingly used in high-stakes domains, there is a growing emphasis placed on making them interpretable to improve trust in these systems. In response, a range of interpretable machine learning (IML)…

Machine Learning · Statistics 2025-05-22 Luqin Gan , Tarek M. Zikry , Genevera I. Allen

Explainability for Large Language Models (LLMs) is a critical yet challenging aspect of natural language processing. As LLMs are increasingly integral to diverse applications, their "black-box" nature sparks significant concerns regarding…

Computation and Language · Computer Science 2024-02-23 Haoyan Luo , Lucia Specia

The challenge of creating interpretable models has been taken up by two main research communities: ML researchers primarily focused on lower-level explainability methods that suit the needs of engineers, and HCI researchers who have more…

Machine Learning · Computer Science 2024-07-16 Juan D. Pinto , Luc Paquette

This paper provides empirical concerns about post-hoc explanations of black-box ML models, one of the major trends in AI explainability (XAI), by showing its lack of interpretability and societal consequences. Using a representative…

Human-Computer Interaction · Computer Science 2021-10-01 Jean-Marie John-Mathews

This work addresses the situation where a black-box model with good predictive performance is chosen over its interpretable competitors, and we show interpretability is still achievable in this case. Our solution is to find an interpretable…

Machine Learning · Computer Science 2019-05-13 Tong Wang

Although a recent shift has been made in the field of predictive process monitoring to use models from the explainable artificial intelligence field, the evaluation still occurs mainly through performance-based metrics, thus not accounting…

Machine Learning · Computer Science 2023-08-01 Alexander Stevens , Johannes De Smedt

Several explainable AI methods allow a Machine Learning user to get insights on the classification process of a black-box model in the form of local linear explanations. With such information, the user can judge which features are locally…

Machine Learning · Computer Science 2023-02-16 Francesco Lomuscio , Paolo Bajardi , Alan Perotti , Elvio G. Amparore

In recent years, machine learning researchers have focused on methods to construct flexible and interpretable prediction models. However, an interpretability evaluation, a relationship between generalization performance and an…

Machine Learning · Computer Science 2019-10-08 Jinwei Zhao , Qizhou Wang , Yufei Wang , Yu Liu , Zhenghao Shi , Xinhong Hei

Machine learning is currently undergoing an explosion in capability, popularity, and sophistication. However, one of the major barriers to widespread acceptance of machine learning (ML) is trustworthiness: most ML models operate as black…