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We propose DeepMiner, a framework to discover interpretable representations in deep neural networks and to build explanations for medical predictions. By probing convolutional neural networks (CNNs) trained to classify cancer in mammograms,…

Computer Vision and Pattern Recognition · Computer Science 2021-11-02 Jimmy Wu , Bolei Zhou , Diondra Peck , Scott Hsieh , Vandana Dialani , Lester Mackey , Genevieve Patterson

While deep neural networks (DNN) have become an effective computational tool, the prediction results are often criticized by the lack of interpretability, which is essential in many real-world applications such as health informatics.…

Computer Vision and Pattern Recognition · Computer Science 2018-05-29 Mengnan Du , Ninghao Liu , Qingquan Song , Xia Hu

In machine learning, exploring data correlations to predict outcomes is a fundamental task. Recognizing causal relationships embedded within data is pivotal for a comprehensive understanding of system dynamics, the significance of which is…

Machine Learning · Computer Science 2023-11-28 Simi Job , Xiaohui Tao , Taotao Cai , Haoran Xie , Lin Li , Jianming Yong , Qing Li

We report a flexible language-model based deep learning strategy, applied here to solve complex forward and inverse problems in protein modeling, based on an attention neural network that integrates transformer and graph convolutional…

Biomolecules · Quantitative Biology 2023-10-20 Markus J. Buehler

Deep neural networks (DNNs) with high expressiveness have achieved state-of-the-art performance in many tasks. However, their distributed feature representations are difficult to interpret semantically. In this work, human-interpretable…

Computer Vision and Pattern Recognition · Computer Science 2019-10-22 Jindong Gu , Volker Tresp

Deep learning models have achieved state-of-the-art performance in many classification tasks. However, most of them cannot provide an interpretation for their classification results. Machine learning models that are interpretable are…

Machine Learning · Computer Science 2021-11-04 Miles Q. Li , Benjamin C. M. Fung , Adel Abusitta

Knowledge graphs represent real-world entities and their relations in a semantically-rich structure supported by ontologies. Exploring this data with machine learning methods often relies on knowledge graph embeddings, which produce latent…

Machine Learning · Computer Science 2023-06-23 Rita T. Sousa , Sara Silva , Catia Pesquita

A variety of methods have been proposed for interpreting nodes in deep neural networks, which typically involve scoring nodes at lower layers with respect to their effects on the output of higher-layer nodes (where lower and higher layers…

Machine Learning · Computer Science 2018-12-04 Jonathan Warrell , Hussein Mohsen , Mark Gerstein

The objective of knowledge graph embedding is to encode both entities and relations of knowledge graphs into continuous low-dimensional vector spaces. Previously, most works focused on symbolic representation of knowledge graph with…

Computation and Language · Computer Science 2016-12-14 Jiacheng Xu , Kan Chen , Xipeng Qiu , Xuanjing Huang

Applying machine learning to molecules is challenging because of their natural representation as graphs rather than vectors.Several architectures have been recently proposed for deep learning from molecular graphs, but they suffer from…

Machine Learning · Statistics 2020-09-15 Jaak Simm , Adam Arany , Edward De Brouwer , Yves Moreau

The widespread use of deep neural networks has achieved substantial success in many tasks. However, there still exists a huge gap between the operating mechanism of deep learning models and human-understandable decision making, so that…

Artificial Intelligence · Computer Science 2021-03-08 Xiaowei Zhou , Jie Yin , Ivor Tsang , Chen Wang

The field of health informatics has been profoundly influenced by the development of random forest models, which have led to significant advances in the interpretability of feature interactions. These models are characterized by their…

Machine Learning · Computer Science 2025-06-04 Akshat Dubey , Aleksandar Anžel , Georges Hattab

Image classification is widely used to build predictive models for breast cancer diagnosis. Most existing approaches overwhelmingly rely on deep convolutional networks to build such diagnosis pipelines. These model architectures, although…

Image and Video Processing · Electrical Eng. & Systems 2022-01-20 Alireza Rezazadeh , Yasamin Jafarian , Ali Kord

Discovery gene-disease links is important in biology and medicine areas, enabling disease identification and drug repurposing. Machine learning approaches accelerate this process by leveraging biological knowledge represented in ontologies…

Machine Learning · Computer Science 2025-04-14 Catarina Canastra , Cátia Pesquita

We developed a tool for visualizing and analyzing large pre-trained vision models by mapping them onto the brain, thus exposing their hidden inside. Our innovation arises from a surprising usage of brain encoding: predicting brain fMRI…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Huzheng Yang , James Gee , Jianbo Shi

Along with the great success of deep neural networks, there is also growing concern about their black-box nature. The interpretability issue affects people's trust on deep learning systems. It is also related to many ethical problems, e.g.,…

Machine Learning · Computer Science 2022-02-01 Yu Zhang , Peter Tiňo , Aleš Leonardis , Ke Tang

To address the challenge of the ``black-box" nature of deep learning in medical settings, we combine GCExplainer - an automated concept discovery solution - along with Logic Explained Networks to provide global explanations for Graph Neural…

The lack of interpretability and transparency are preventing economists from using advanced tools like neural networks in their empirical research. In this paper, we propose a class of interpretable neural network models that can achieve…

Econometrics · Economics 2020-12-01 Yucheng Yang , Zhong Zheng , Weinan E

Interpretability in Graph Convolutional Networks (GCNs) has been explored to some extent in computer vision in general, yet, in the medical domain, it requires further examination. Moreover, most of the interpretability approaches for GCNs,…

Computer Vision and Pattern Recognition · Computer Science 2021-03-30 Anees Kazi , Soroush Farghadani , Nassir Navab

We present Supervised Deep Multimodal Matrix Factorization (SD3MF), an interpretable framework for integrative brain network analysis that generalizes Symmetric Nonnegative Matrix Tri-Factorization (SNMTF) from unsupervised single-graph…

Machine Learning · Computer Science 2026-05-14 Amjad Seyedi , Lifang He , Songlin Zhao , Akwum Onwunta , Nicolas Gillis