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We study the problem of estimating causal effects under hidden confounding in the following unpaired data setting: we observe some covariates $X$ and an outcome $Y$ under different experimental conditions (environments) but do not observe…

Machine Learning · Statistics 2026-01-22 Felix Schur , Niklas Pfister , Peng Ding , Sach Mukherjee , Jonas Peters

Cross-site generalizability in medical AI is fundamentally compromised by selection bias, a structural mechanism where patient demographics (e.g., age, severity) non-randomly dictate hospital assignment. Conventional Domain Generalization…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Shaojin Bai , Yuting Su , Weizhi Nie

We develop a method to perform model averaging in two-stage linear regression systems subject to endogeneity. Our method extends an existing Gibbs sampler for instrumental variables to incorporate a component of model uncertainty. Direct…

Methodology · Statistics 2012-03-20 Anna Karl , Alex Lenkoski

Sound and complete algorithms have been proposed to compute identifiable causal queries using the causal structure and data. However, most of these algorithms assume accurate estimation of the data distribution, which is impractical for…

Machine Learning · Computer Science 2024-10-29 Md Musfiqur Rahman , Murat Kocaoglu

Unmeasured or latent variables are often the cause of correlations between multivariate measurements, which are studied in a variety of fields such as psychology, ecology, and medicine. For Gaussian measurements, there are classical tools…

Machine Learning · Computer Science 2022-01-28 Łukasz Kidziński , Francis K. C. Hui , David I. Warton , Trevor Hastie

Mixture models are a fundamental tool in applied statistics and machine learning for treating data taken from multiple subpopulations. The current practice for estimating the parameters of such models relies on local search heuristics…

Machine Learning · Computer Science 2012-09-07 Animashree Anandkumar , Daniel Hsu , Sham M. Kakade

Instrumental variables (IVs) provide a powerful strategy for identifying causal effects in the presence of unobservable confounders. Within the nonparametric setting (NPIV), recent methods have been based on nonlinear generalizations of…

Machine Learning · Statistics 2024-12-24 Yuri Fonseca , Caio Peixoto , Yuri Saporito

In the estimation of causal effects, one common method for removing the influence of confounders is to adjust the variables that satisfy the back-door criterion. However, it is not always possible to uniquely determine sets of such…

Machine Learning · Computer Science 2025-02-06 Atsushi Noda , Takashi Isozaki

Condition and structural health monitoring (CM/SHM) is a pivotal component of predictive maintenance (PdM) strategies across diverse industrial sectors, including mechanical rotating machinery, aircraft structures, wind turbines, and civil…

Computational Engineering, Finance, and Science · Computer Science 2026-02-17 Xin Yang , Chen Fang , Yunlai Liao , Jian Yang , Konstantinos Gryllias , Dimitrios Chronopoulos

Instrumental variable methods provide useful tools for inferring causal effects in the presence of unmeasured confounding. To apply these methods with large-scale data sets, a major challenge is to find valid instruments from a possibly…

Methodology · Statistics 2024-09-24 Xinyi Zhang , Linbo Wang , Stanislav Volgushev , Dehan Kong

The ability to learn disentangled representations that split underlying sources of variation in high dimensional, unstructured data is important for data efficient and robust use of neural networks. While various approaches aiming towards…

Machine Learning · Statistics 2019-05-15 Raphael Suter , Đorđe Miladinović , Bernhard Schölkopf , Stefan Bauer

Deep neural networks (DNN) have been used successfully in many scientific problems for their high prediction accuracy, but their application to genetic studies remains challenging due to their poor interpretability. In this paper, we…

Machine Learning · Computer Science 2021-10-01 Peyman H. Kassani , Fred Lu , Yann Le Guen , Zihuai He

In this conceptual work, we present Deep Convolutional Gaussian Mixture Models (DCGMMs): a new formulation of deep hierarchical Gaussian Mixture Models (GMMs) that is particularly suitable for describing and generating images. Vanilla…

Computer Vision and Pattern Recognition · Computer Science 2021-04-27 Alexander Gepperth , Benedikt Pfülb

Instrumental variable (IV) and proximal causal learning (Proxy) methods are central frameworks for causal inference in the presence of unobserved confounding. Despite substantial methodological advances, existing approaches rarely provide…

Machine Learning · Statistics 2026-03-03 Yuqi Zhang , Krikamol Muandet , Dino Sejdinovic , Edwin Fong , Siu Lun Chau

Many weak instrumental variables (IVs) are routinely used in the health and social sciences to improve identification and inference of the treatment effect of interest, along with a broad collection of data on potential confounding factors…

Methodology · Statistics 2026-04-16 Di Zhang , Xuanyu Li , Baoluo Sun

Deep feedforward neural networks (DFNNs) are a powerful tool for functional approximation. We describe flexible versions of generalized linear and generalized linear mixed models incorporating basis functions formed by a DFNN. The…

Computation · Statistics 2018-05-28 Minh-Ngoc Tran , Nghia Nguyen , David Nott , Robert Kohn

Instrumental variable methods are widely used for inferring the causal effect in the presence of unmeasured confounders. Existing instrumental variable methods for nonlinear outcome models require stringent identifiability conditions. This…

Methodology · Statistics 2022-07-01 Sai Li , Zijian Guo

Debiased machine learning (DML) offers an attractive way to estimate treatment effects in observational settings, where identification of causal parameters requires a conditional independence or unconfoundedness assumption, since it allows…

Econometrics · Economics 2022-06-16 Victor Quintas-Martinez

The variance-based method of Sobol sensitivity indices is very popular among practitioners due to its efficiency and easiness of interpretation. However, for high-dimensional models the direct application of this method can be very time…

Statistics Theory · Mathematics 2016-05-26 S. Kucherenko , S. Song

While synthetic data hold great promise for privacy protection, their statistical analysis poses significant challenges that necessitate innovative solutions. The use of deep generative models (DGMs) for synthetic data generation is known…

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