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Underpinning the past decades of work on the design, initialization, and optimization of neural networks is a seemingly innocuous assumption: that the network is trained on a \textit{stationary} data distribution. In settings where this…

Machine Learning · Computer Science 2024-03-01 Clare Lyle , Zeyu Zheng , Khimya Khetarpal , Hado van Hasselt , Razvan Pascanu , James Martens , Will Dabney

Rapidly learning from ongoing experiences and remembering past events with a flexible memory system are two core capacities of biological intelligence. While the underlying neural mechanisms are not fully understood, various evidence…

Neural and Evolutionary Computing · Computer Science 2023-02-08 Yu Duan , Zhongfan Jia , Qian Li , Yi Zhong , Kaisheng Ma

Understanding how long-term stimulation reshapes neural circuits requires uncovering the rules of brain plasticity. While short-term synaptic modifications have been extensively characterized, the principles that drive circuit-level…

Neurons and Cognition · Quantitative Biology 2026-03-03 Zhichao Liang , Jingzhe Lin , Xinyi Li , Guanyi Zhao , Quanying Liu

Biological neurons and their in-silico emulations for neuromorphic artificial intelligence (AI) use extraordinarily energy-efficient mechanisms, such as spike-based communication and local synaptic plasticity. It remains unclear whether…

Neural and Evolutionary Computing · Computer Science 2021-06-17 Timoleon Moraitis , Abu Sebastian , Evangelos Eleftheriou

Continuous adaptation allows survival in an ever-changing world. Adjustments in the synaptic coupling strength between neurons are essential for this capability, setting us apart from simpler, hard-wired organisms. How these changes can be…

Neurons and Cognition · Quantitative Biology 2021-01-06 Jakob Jordan , Maximilian Schmidt , Walter Senn , Mihai A. Petrovici

Animal behaviour depends on learning to associate sensory stimuli with the desired motor command. Understanding how the brain orchestrates the necessary synaptic modifications across different brain areas has remained a longstanding puzzle.…

Neurons and Cognition · Quantitative Biology 2018-01-03 João Sacramento , Rui Ponte Costa , Yoshua Bengio , Walter Senn

Despite the striking successes of deep neural networks trained with gradient-based optimization, these methods differ fundamentally from their biological counterparts. This gap raises key questions about how nature achieves robust,…

Machine Learning · Computer Science 2025-10-15 Mattia Scardecchia

Spiking activity of neurons engaged in learning and performing a task show complex spatiotemporal dynamics. While the output of recurrent network models can learn to perform various tasks, the possible range of recurrent dynamics that…

Neurons and Cognition · Quantitative Biology 2018-08-21 Christopher Kim , Carson Chow

Brain-inspired machine intelligence research seeks to develop computational models that emulate the information processing and adaptability that distinguishes biological systems of neurons. This has led to the development of spiking neural…

Neural and Evolutionary Computing · Computer Science 2024-10-28 Alexander Ororbia

Biological neural networks are characterized by their high degree of plasticity, a core property that enables the remarkable adaptability of natural organisms. Importantly, this ability affects both the synaptic strength and the topology of…

Neural and Evolutionary Computing · Computer Science 2024-06-17 Erwan Plantec , Joachin W. Pedersen , Milton L. Montero , Eleni Nisioti , Sebastian Risi

The dynamics of local cortical networks are irregular, but correlated. Dynamic excitatory--inhibitory balance is a plausible mechanism that generates such irregular activity, but it remains unclear how balance is achieved and maintained in…

Neurons and Cognition · Quantitative Biology 2020-04-28 Alan Eric Akil , Robert Rosenbaum , Krešimir Josić

Neural plasticity is an important functionality of human brain, in which number of neurons and synapses can shrink or expand in response to stimuli throughout the span of life. We model this dynamic learning process as an $L_0$-norm…

Neural and Evolutionary Computing · Computer Science 2021-05-04 Yang Li , Shihao Ji

Deep neural networks have achieved impressive performance through carefully engineered training strategies. Nonetheless, such methods lack parallels in biological neural circuits, relying heavily on non-local credit assignment, precise…

Neurons and Cognition · Quantitative Biology 2025-04-08 Navid Shervani-Tabar , Marzieh Alireza Mirhoseini , Robert Rosenbaum

How neuronal circuits achieve credit assignment remains a central unsolved question in systems neuroscience. Various studies have suggested plausible solutions for back-propagating error signals through multi-layer networks. These purely…

Neurons and Cognition · Quantitative Biology 2023-12-12 Julian Rossbroich , Friedemann Zenke

Deep learning has seen remarkable developments over the last years, many of them inspired by neuroscience. However, the main learning mechanism behind these advances - error backpropagation - appears to be at odds with neurobiology. Here,…

Neurons and Cognition · Quantitative Biology 2018-10-29 João Sacramento , Rui Ponte Costa , Yoshua Bengio , Walter Senn

Deep artificial neural networks famously struggle to learn from non-stationary streams of data. Without dedicated mitigation strategies, continual learning is associated with continuous forgetting of previous tasks and a progressive loss of…

Neurons and Cognition · Quantitative Biology 2025-12-29 Suzanne van der Veldt , Gido M. van de Ven , Sanne Moorman , Guillaume Etter

A fundamental aspect of learning in biological neural networks is the plasticity property which allows them to modify their configurations during their lifetime. Hebbian learning is a biologically plausible mechanism for modeling the…

Neural and Evolutionary Computing · Computer Science 2021-03-16 Anil Yaman , Giovanni Iacca , Decebal Constantin Mocanu , Matt Coler , George Fletcher , Mykola Pechenizkiy

Spike Timing Dependent Plasticity is form of learning that has been demonstrated in real cortical tissue, but attempts to use it for artificial systems have not produced good results. This paper seeks to remedy this with two significant…

Neural and Evolutionary Computing · Computer Science 2020-07-01 Simon Davidson , Stephen B. Furber , Oliver Rhodes

Thought to be responsible for memory, synaptic plasticity has been widely studied in the past few decades. One example of plasticity models is the popular Spike Timing Dependent Plasticity (STDP). The huge litterature of STDP models are…

Probability · Mathematics 2018-03-02 Pascal Helson

There is a concerted effort to build domain-general artificial intelligence in the form of universal neural network models with sufficient computational flexibility to solve a wide variety of cognitive tasks but without requiring…

Neural and Evolutionary Computing · Computer Science 2023-03-27 Jascha Achterberg , Danyal Akarca , Moataz Assem , Moritz Heimbach , Duncan E. Astle , John Duncan