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In conventional tomographic reconstruction, the pre-processing step includes flat-field correction, where each sample projection on the detector is divided by a reference image taken without the sample. When using coherent X-rays as probe,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Viktor Nikitin , Marcus Carlsson , Doga Gursoy , Rajmund Mokso , Peter Cloetens

Modern technology for producing extremely bright and coherent X-ray laser pulses provides the possibility to acquire a large number of diffraction patterns from individual biological nanoparticles, including proteins, viruses, and DNA.…

Methodology · Statistics 2018-07-11 Stefan Engblom , Carl Nettelblad , Jing Liu

A solution to the inversion problem of scattering would offer aberration-free diffraction-limited 3D images without the resolution and depth-of-field limitations of lens-based tomographic systems. Powerful algorithms are increasingly being…

Scanning X-ray nanodiffraction microscopy is a powerful technique for spatially resolving nanoscale structural morphologies by diffraction contrast. One of the critical challenges in experimental nanodiffraction data analysis is posed by…

Applied Physics · Physics 2024-06-26 Aileen Luo , Tao Zhou , Martin V. Holt , Andrej Singer , Mathew J. Cherukara

Fourier ptychography is a recently developed imaging approach for large field-of-view and high-resolution microscopy. Here we model the Fourier ptychographic forward imaging process using a convolution neural network (CNN) and recover the…

Computer Vision and Pattern Recognition · Computer Science 2018-03-12 Shaowei Jiang , Kaikai Guo , Jun Liao , Guoan Zheng

We demonstrate a motion-free intensity diffraction tomography technique that enables direct inversion of 3D phase and absorption from intensity-only measurements for weakly scattering samples. We derive a novel linear forward model,…

Image and Video Processing · Electrical Eng. & Systems 2018-06-26 Ruilong Ling , Waleed Tahir , Hsing-Ying Lin , Hakho Lee , Lei Tian

X-ray ptychography is one of the versatile techniques for nanometer resolution imaging. The magnitude of the diffraction patterns is recorded on a detector and the phase of the diffraction patterns is estimated using phase retrieval…

Image and Video Processing · Electrical Eng. & Systems 2021-05-21 Prasan Shedligeri , Florian Schiffers , Semih Barutcu , Pablo Ruiz , Aggelos K Katsaggelos , Oliver Cossairt

Single-shot X-ray imaging of short-lived nanostructures such as clusters and nanoparticles near a phase transition or non-crystalizing objects such as large proteins and viruses is currently the most elegant method for characterizing their…

Atomic and Molecular Clusters · Physics 2020-10-14 Thomas Stielow , Robin Schmidt , Christian Peltz , Thomas Fennel , Stefan Scheel

Ptychography is a lensless imaging method that allows for wavefront sensing and phase-sensitive microscopy from a set of diffraction patterns. Recently, it has been shown that the optimization task in ptychography can be achieved via…

Image and Video Processing · Electrical Eng. & Systems 2021-01-13 Jacob Seifert , Dorian Bouchet , Lars Loetgering , Allard P. Mosk

A unified method for three-dimensional reconstruction of objects from transmission images collected at multiple illumination directions is described. The method may be applicable to experimental conditions relevant to absorption-based,…

Medical Physics · Physics 2022-12-07 Timur E. Gureyev , Hamish G. Brown , Harry M. Quiney , Leslie J. Allen

This article presents a method to perform diffraction tomography in a standard microscope that includes an LED array for illumination. After acquiring a sequence of intensity-only images of a thick sample, a ptychography-based…

Optics · Physics 2015-10-30 Roarke Horstmeyer , Changhuei Yang

Density reconstruction from X-ray projections is an important problem in radiography with key applications in scientific and industrial X-ray computed tomography (CT). Often, such projections are corrupted by unknown sources of noise and…

Image and Video Processing · Electrical Eng. & Systems 2026-02-26 Siddhant Gautam , Marc L. Klasky , Balasubramanya T. Nadiga , Trevor Wilcox , Gary Salazar , Saiprasad Ravishankar

Coherent imaging techniques such as ptychography offer powerful capabilities for 3D resolution of nanoscale structures. By application in grazing incidence, such techniques may achieve exceptional surface sensitivity as demonstrated by…

Three-dimensional inspection of nanostructures such as integrated circuits is important for security and reliability assurance. Two scanning operations are required: ptychographic to recover the complex transmissivity of the specimen; and…

Image and Video Processing · Electrical Eng. & Systems 2024-08-15 Iksung Kang , Yi Jiang , Mirko Holler , Manuel Guizar-Sicairos , A. F. J. Levi , Jeffrey Klug , Stefan Vogt , George Barbastathis

Tomography is the three-dimensional reconstruction of an object from images taken at different angles. The term classical tomography is used, when the imaging beam travels in straight lines through the object. This assumption is valid for…

Quantitative Methods · Quantitative Biology 2016-10-10 Paul Müller , Mirjam Schürmann , Jochen Guck

Deep learning methods for accelerated MRI achieve state-of-the-art results but largely ignore additional speedups possible with noncartesian sampling trajectories. To address this gap, we created a generative diffusion model-based…

Artificial Intelligence · Computer Science 2024-10-02 Trevor J. Chan , Chamith S. Rajapakse

To date, high-resolution (< 1 nm) imaging of extended objects in three-dimensions (3D) has not been possible. A restriction known as the Crowther criterion forces a tradeoff between object size and resolution for 3D reconstructions by…

Materials Science · Physics 2014-11-20 Robert Hovden , Peter Ercius , Yi Jiang , Deli Wang , Yingchao Yu , Hector D. Abruna , Veit Elser , David A. Muller

Image reconstruction under multiple light scattering is crucial in a number of applications such as diffraction tomography. The reconstruction problem is often formulated as a nonconvex optimization, where a nonlinear measurement model is…

Computer Vision and Pattern Recognition · Computer Science 2018-07-04 Yu Sun , Zhihao Xia , Ulugbek S. Kamilov

Ptychography, a coherent diffraction imaging technique, has become an indispensable tool in materials characterization, biological imaging, and nanostructure analysis due to its capability for high-resolution, lensless reconstruction of…

In this work, we develop a novel technique for reconstructing images from projection-based nano- and microtomography. Our contribution focuses on enhancing reconstruction quality, particularly for specimen composed of homogeneous material…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Anuraag Mishra , Andrea Gilch , Benjamin Apeleo Zubiri , Jan Rolfes , Frauke Liers
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