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A molecule's geometry, also known as conformation, is one of a molecule's most important properties, determining the reactions it participates in, the bonds it forms, and the interactions it has with other molecules. Conventional…

Machine Learning · Computer Science 2020-01-01 Elman Mansimov , Omar Mahmood , Seokho Kang , Kyunghyun Cho

Graph learning plays a central role in many data mining and machine learning tasks, such as manifold learning, data representation and analysis, dimensionality reduction, clustering, and visualization. In this work, we propose a highly…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Yongyu Wang

We present a novel approach to image manipulation and understanding by simultaneously learning to segment object masks, paste objects to another background image, and remove them from original images. For this purpose, we develop a novel…

Computer Vision and Pattern Recognition · Computer Science 2019-01-17 Pavel Ostyakov , Roman Suvorov , Elizaveta Logacheva , Oleg Khomenko , Sergey I. Nikolenko

Learning expressive molecular representations is crucial to facilitate the accurate prediction of molecular properties. Despite the significant advancement of graph neural networks (GNNs) in molecular representation learning, they generally…

Machine Learning · Computer Science 2023-05-19 Hossein Hajiabolhassan , Zahra Taheri , Ali Hojatnia , Yavar Taheri Yeganeh

Despite the rapid development of adversarial machine learning, most adversarial attack and defense researches mainly focus on the perturbation-based adversarial examples, which is constrained by the input images. In comparison with existing…

Computer Vision and Pattern Recognition · Computer Science 2020-02-10 Xiaosen Wang , Kun He , Chuanbiao Song , Liwei Wang , John E. Hopcroft

Deep learning has emerged as a key tool for designing nanophotonic structures that manipulate light at sub-wavelength scales. We investigate how to inversely design plasmonic nanostructures using conditional generative adversarial networks.…

Optics · Physics 2026-05-21 Petter Persson , Nils Henriksson , Nicolò Maccaferri

Neural networks are known to be susceptible to adversarial samples: small variations of natural examples crafted to deliberately mislead the models. While they can be easily generated using gradient-based techniques in digital and physical…

Computer Vision and Pattern Recognition · Computer Science 2024-01-18 Haotian Xue , Alexandre Araujo , Bin Hu , Yongxin Chen

In the past decades, intensive efforts have been put to design various loss functions and metric forms for metric learning problem. These improvements have shown promising results when the test data is similar to the training data. However,…

Machine Learning · Computer Science 2018-02-12 Shuo Chen , Chen Gong , Jian Yang , Xiang Li , Yang Wei , Jun Li

Deep generative models learned through adversarial training have become increasingly popular for their ability to generate naturalistic image textures. However, aside from their texture, the visual appearance of objects is significantly…

Computer Vision and Pattern Recognition · Computer Science 2018-03-29 Jean Kossaifi , Linh Tran , Yannis Panagakis , Maja Pantic

Adversarial examples are a hot topic due to their abilities to fool a classifier's prediction. There are two strategies to create such examples, one uses the attacked classifier's gradients, while the other only requires access to the…

Machine Learning · Computer Science 2020-01-29 Jean-Christophe Burnel , Kilian Fatras , Nicolas Courty

Data-driven prediction of molecular properties presents unique challenges to the design of machine learning methods concerning data structure/dimensionality, symmetry adaption, and confidence management. In this paper, we present a…

Machine Learning · Computer Science 2019-01-31 Yu-Hang Tang , Wibe A. de Jong

Combination therapy has shown to improve therapeutic efficacy while reducing side effects. Importantly, it has become an indispensable strategy to overcome resistance in antibiotics, anti-microbials, and anti-cancer drugs. Facing enormous…

Molecular Networks · Quantitative Biology 2020-04-24 Mostafa Karimi , Arman Hasanzadeh , Yang shen

One significant challenge of exploiting Graph neural networks (GNNs) in real-life scenarios is that they are always treated as black boxes, therefore leading to the requirement of interpretability. To address this, model-level…

Machine Learning · Computer Science 2025-09-22 Xiao Yue , Guangzhi Qu , Lige Gan

Data-free Knowledge Distillation (DFKD) is a method that constructs pseudo-samples using a generator without real data, and transfers knowledge from a teacher model to a student by enforcing the student to overcome dimensional differences…

Machine Learning · Computer Science 2025-04-03 Yuang Jia , Xiaojuan Shan , Jun Xia , Guancheng Wan , Yuchen Zhang , Wenke Huang , Mang Ye , Stan Z. Li

Adversarial attacks on Graph Neural Networks aim to perturb the performance of the learner by carefully modifying the graph topology and node attributes. Existing methods achieve attack stealthiness by constraining the modification budget…

Machine Learning · Computer Science 2025-06-10 Kai Yuan , Jiahao Zhang , Yidi Wang , Xiaobing Pei

Deep learning based approaches have been utilized to model and generate graphs subjected to different distributions recently. However, they are typically unsupervised learning based and unconditioned generative models or simply conditioned…

Machine Learning · Computer Science 2023-08-29 Shanchao Yang , Jing Liu , Kai Wu , Mingming Li

Molecule generation is a very important practical problem, with uses in drug discovery and material design, and AI methods promise to provide useful solutions. However, existing methods for molecule generation focus either on 2D graph…

Machine Learning · Computer Science 2024-02-07 Chenqing Hua , Sitao Luan , Minkai Xu , Rex Ying , Jie Fu , Stefano Ermon , Doina Precup

Machine Learning has been applied in a wide range of tasks throughout the last years, ranging from image classification to autonomous driving and natural language processing. Restricted Boltzmann Machine (RBM) has received recent attention…

Machine Learning · Computer Science 2021-01-05 Gustavo H. de Rosa , Mateus Roder , João P. Papa

Leveraging domain knowledge including fingerprints and functional groups in molecular representation learning is crucial for chemical property prediction and drug discovery. When modeling the relation between graph structure and molecular…

Machine Learning · Computer Science 2021-03-25 Yin Fang , Haihong Yang , Xiang Zhuang , Xin Shao , Xiaohui Fan , Huajun Chen

Generating molecules with desired chemical properties presents a critical challenge in fields such as chemical synthesis and drug discovery. Recent advancements in artificial intelligence (AI) and deep learning have significantly…

Machine Learning · Computer Science 2025-09-25 Chen Li , Huidong Tang , Ye Zhu , Yoshihiro Yamanishi