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Generative adversarial networks have gained a lot of attention in the computer vision community due to their capability of data generation without explicitly modelling the probability density function. The adversarial loss brought by the…

Computer Vision and Pattern Recognition · Computer Science 2019-09-05 Xin Yi , Ekta Walia , Paul Babyn

Generative Adversarial Network (GAN) can be viewed as an implicit estimator of a data distribution, and this perspective motivates using the adversarial concept in the true input parameter estimation of black-box generators. While previous…

Machine Learning · Computer Science 2020-06-12 Dongjun Kim , Weonyoung Joo , Seungjae Shin , Kyungwoo Song , Il-Chul Moon

Designing new molecules with a set of predefined properties is a core problem in modern drug discovery and development. There is a growing need for de-novo design methods that would address this problem. We present MolecularRNN, the graph…

Machine Learning · Computer Science 2019-06-03 Mariya Popova , Mykhailo Shvets , Junier Oliva , Olexandr Isayev

Graph Neural Networks (GNNs) have been widely employed for feature representation learning in molecular graphs. Therefore, it is crucial to enhance the expressiveness of feature representation to ensure the effectiveness of GNNs. However, a…

Machine Learning · Computer Science 2024-09-16 Chengyu Yao , Hong Huang , Hang Gao , Fengge Wu , Haiming Chen , Junsuo Zhao

The rational design of molecules with desired properties is a long-standing challenge in chemistry. Generative neural networks have emerged as a powerful approach to sample novel molecules from a learned distribution. Here, we propose a…

Adversarial attacks from generative models often produce low-quality images and require substantial computational resources. Diffusion models, though capable of high-quality generation, typically need hundreds of sampling steps for…

Computer Vision and Pattern Recognition · Computer Science 2025-08-22 Susim Roy , Anubhooti Jain , Mayank Vatsa , Richa Singh

It is well known that Drug Design is often a costly process both in terms of time and economic effort. While good Quantitative Structure-Activity Relationship models (QSAR) can help predicting molecular properties without the need to…

Biomolecules · Quantitative Biology 2022-02-14 Dylan Savoia , Alessio Ragno , Roberto Capobianco

Node representation learning for directed graphs is critically important to facilitate many graph mining tasks. To capture the directed edges between nodes, existing methods mostly learn two embedding vectors for each node, source vector…

Social and Information Networks · Computer Science 2021-05-25 Shijie Zhu , Jianxin Li , Hao Peng , Senzhang Wang , Lifang He

The utility of machine learning (ML) techniques in materials science has accelerated materials design and discovery. However, the accuracy of ML models - particularly deep neural networks - heavily relies on the quality and quantity of the…

Materials Science · Physics 2023-10-25 Marzie Ghorbani , Zhipeng Li , Nick Birbilis

View missing remains a significant challenge in graph-based multi-view semi-supervised learning, hindering their real-world applications. To address this issue, traditional methods introduce a missing indicator matrix and focus on mining…

Machine Learning · Computer Science 2025-10-22 Zhangqi Jiang , Tingjin Luo , Xu Yang , Xinyan Liang

Learning a faithful directed acyclic graph (DAG) from samples of a joint distribution is a challenging combinatorial problem, owing to the intractable search space superexponential in the number of graph nodes. A recent breakthrough…

Machine Learning · Computer Science 2019-04-24 Yue Yu , Jie Chen , Tian Gao , Mo Yu

Generative Adversarial Networks (GANs), as a framework for estimating generative models via an adversarial process, have attracted huge attention and have proven to be powerful in a variety of tasks. However, training GANs is well known for…

Machine Learning · Computer Science 2017-11-09 Zi-Yi Dou

The goal of graph representation learning is to embed each vertex in a graph into a low-dimensional vector space. Existing graph representation learning methods can be classified into two categories: generative models that learn the…

Machine Learning · Computer Science 2017-11-23 Hongwei Wang , Jia Wang , Jialin Wang , Miao Zhao , Weinan Zhang , Fuzheng Zhang , Xing Xie , Minyi Guo

Molecular representation learning is a crucial task in predicting molecular properties. Molecules are often modeled as graphs where atoms and chemical bonds are represented as nodes and edges, respectively, and Graph Neural Networks (GNNs)…

Machine Learning · Computer Science 2023-05-23 Jiahao Chen , Yurou Liu , Jiangmeng Li , Bing Su , Jirong Wen

This paper studies the rates of convergence for learning distributions implicitly with the adversarial framework and Generative Adversarial Networks (GANs), which subsume Wasserstein, Sobolev, MMD GAN, and Generalized/Simulated Method of…

Statistics Theory · Mathematics 2021-10-12 Tengyuan Liang

Machine learning techniques have recently been adopted in various applications in medicine, biology, chemistry, and material engineering. An important task is to predict the properties of molecules, which serves as the main subroutine in…

Machine Learning · Computer Science 2019-11-12 Shengchao Liu , Mehmet Furkan Demirel , Yingyu Liang

Imbalanced classification on graphs is ubiquitous yet challenging in many real-world applications, such as fraudulent node detection. Recently, graph neural networks (GNNs) have shown promising performance on many network analysis tasks.…

Machine Learning · Computer Science 2021-06-08 Liang Qu , Huaisheng Zhu , Ruiqi Zheng , Yuhui Shi , Hongzhi Yin

We study how to generate molecule conformations (i.e., 3D structures) from a molecular graph. Traditional methods, such as molecular dynamics, sample conformations via computationally expensive simulations. Recently, machine learning…

Machine Learning · Computer Science 2021-04-01 Minkai Xu , Shitong Luo , Yoshua Bengio , Jian Peng , Jian Tang

Adversarial examples pose many security threats to convolutional neural networks (CNNs). Most defense algorithms prevent these threats by finding differences between the original images and adversarial examples. However, the found…

Computer Vision and Pattern Recognition · Computer Science 2022-01-27 Li Chen , Qi Li , Weiye Chen , Zeyu Wang , Haifeng Li

This paper studies how well generative adversarial networks (GANs) learn probability distributions from finite samples. Our main results establish the convergence rates of GANs under a collection of integral probability metrics defined…

Machine Learning · Computer Science 2022-06-10 Jian Huang , Yuling Jiao , Zhen Li , Shiao Liu , Yang Wang , Yunfei Yang