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Gene expression data represents a unique challenge in predictive model building, because of the small number of samples $(n)$ compared to the huge amount of features $(p)$. This "$n<<p$" property has hampered application of deep learning…

Machine Learning · Statistics 2018-02-13 Yunchuan Kong , Tianwei Yu

Omics data, such as transcriptomics, proteomics, and metabolomics, provide critical insights into disease mechanisms and clinical outcomes. However, their high dimensionality, small sample sizes, and intricate biological networks pose major…

Machine Learning · Computer Science 2026-01-22 Tiantian Yang , Yuxuan Wang , Zhenwei Zhou , Ching-Ti Liu

There are two fundamental problems in applying deep learning/machine learning methods to disease classification tasks, one is the insufficient number and poor quality of training samples; another one is how to effectively fuse multiple…

Machine Learning · Computer Science 2023-07-25 Menglin Kong , Shaojie Zhao , Juan Cheng , Xingquan Li , Ri Su , Muzhou Hou , Cong Cao

Automatic building extraction from optical imagery remains a challenge due to, for example, the complexity of building shapes. Semantic segmentation is an efficient approach for this task. The latest development in deep convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2019-11-11 Yilei Shi , Qingyu Li , Xiao Xiang Zhu

Spectral graph convolutional neural networks (GCNNs) have been producing encouraging results in graph classification tasks. However, most spectral GCNNs utilize fixed graphs when aggregating node features, while omitting edge feature…

Computer Vision and Pattern Recognition · Computer Science 2022-10-06 Yang Yi , Xuequan Lu , Shang Gao , Antonio Robles-Kelly , Yuejie Zhang

Building predictive models for tabular data presents fundamental challenges, notably in scaling consistently, i.e., more resources translating to better performance, and generalizing systematically beyond the training data distribution.…

Despite the popularity of deep learning, structure learning for deep models remains a relatively under-explored area. In contrast, structure learning has been studied extensively for probabilistic graphical models (PGMs). In particular, an…

Machine Learning · Computer Science 2018-03-19 Zhourong Chen , Xiaopeng Li , Nevin L. Zhang

Deep Learning is considered to be a quite young in the area of machine learning research, found its effectiveness in dealing complex yet high dimensional dataset that includes but limited to images, text and speech etc. with multiple levels…

Computer Vision and Pattern Recognition · Computer Science 2016-10-19 Mrutyunjaya Panda

General graphs are difficult for learning due to their irregular structures. Existing works employ message passing along graph edges to extract local patterns using customized graph kernels, but few of them are effective for the integration…

Computer Vision and Pattern Recognition · Computer Science 2020-07-23 Yecheng Lyu , Ming Li , Xinming Huang , Ulkuhan Guler , Patrick Schaumont , Ziming Zhang

This work presents a novel resolution-invariant model order reduction strategy for multifidelity applications. We base our architecture on a novel neural network layer developed in this work, the graph feedforward network, which extends the…

Numerical Analysis · Mathematics 2024-06-07 Oisín M. Morrison , Federico Pichi , Jan S. Hesthaven

We target open-world feature extrapolation problem where the feature space of input data goes through expansion and a model trained on partially observed features needs to handle new features in test data without further retraining. The…

Machine Learning · Computer Science 2023-06-14 Qitian Wu , Chenxiao Yang , Junchi Yan

Integration and analysis of multi-omics data provide valuable insights for improving cancer subtype classification. However, such data are inherently heterogeneous, high-dimensional, and exhibit complex intra- and inter-modality…

Quantitative Methods · Quantitative Biology 2026-02-13 Tiantian Yang , Zhiqian Chen

We consider the problem of learning efficient and inductive graph convolutional networks for text classification with a large number of examples and features. Existing state-of-the-art graph embedding based methods such as predictive text…

Computation and Language · Computer Science 2020-09-01 Rahul Ragesh , Sundararajan Sellamanickam , Arun Iyer , Ram Bairi , Vijay Lingam

Graph, as an important data representation, is ubiquitous in many real world applications ranging from social network analysis to biology. How to correctly and effectively learn and extract information from graph is essential for a large…

Machine Learning · Computer Science 2020-10-27 Xiaodong Jiang , Ronghang Zhu , Pengsheng Ji , Sheng Li

Various Graph Neural Networks (GNNs) have been successful in analyzing data in non-Euclidean spaces, however, they have limitations such as oversmoothing, i.e., information becomes excessively averaged as the number of hidden layers…

Machine Learning · Computer Science 2024-01-23 Jaeyoon Sim , Sooyeon Jeon , InJun Choi , Guorong Wu , Won Hwa Kim

Federated Graph Learning (FGL) is an emerging technology that enables clients to collaboratively train powerful Graph Neural Networks (GNNs) in a distributed manner without exposing their private data. Nevertheless, FGL still faces the…

Machine Learning · Computer Science 2024-08-22 Longwen Wang , Jianchun Liu , Zhi Liu , Jinyang Huang

Networks are ubiquitous structure that describes complex relationships between different entities in the real world. As a critical component of prediction task over nodes in networks, learning the feature representation of nodes has become…

Machine Learning · Computer Science 2018-09-10 Hansheng Xue , Jiajie Peng , Xuequn Shang

Graph Convolutional Neural Networks (GCNs) are widely used for graph analysis. Specifically, in medical applications, GCNs can be used for disease prediction on a population graph, where graph nodes represent individuals and edges represent…

Machine Learning · Computer Science 2022-07-19 Liang Peng , Nan Wang , Nicha Dvornek , Xiaofeng Zhu , Xiaoxiao Li

Identifying influential nodes in complex networks is of great importance, and has many applications in practice. For example, finding influential nodes in e-commerce network can provide merchants with customers with strong purchase intent;…

Social and Information Networks · Computer Science 2025-08-05 Yanmei Hu , Siyuan Yin , Yihang Wu , Xue Yue , Yue Liu

We propose a novel approach to enhance the discriminability of Convolutional Neural Networks (CNN). The key idea is to build a tree structure that could progressively learn fine-grained features to distinguish a subset of classes, by…

Computer Vision and Pattern Recognition · Computer Science 2017-09-25 Zhenhua Wang , Xingxing Wang , Gang Wang
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