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4D-STEM, in which the 2D diffraction plane is captured for each 2D scan position in the scanning transmission electron microscope (STEM) using a pixelated detector, is complementing and increasingly replacing existing imaging approaches.…

Instrumentation and Detectors · Physics 2022-07-27 Colum M. O'Leary , Benedikt Haas , Christoph T. Koch , Peter D. Nellist , Lewys Jones

We present StableMotion, a novel framework leverages knowledge (geometry and content priors) from pretrained large-scale image diffusion models to perform motion estimation, solving single-image-based image rectification tasks such as…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Ziyi Wang , Haipeng Li , Lin Sui , Tianhao Zhou , Hai Jiang , Lang Nie , Shuaicheng Liu

We present STARRED, a Point Spread Function (PSF) reconstruction, two-channel deconvolution, and light curve extraction method designed for high-precision photometric measurements in imaging time series. An improved resolution of the data…

Instrumentation and Methods for Astrophysics · Physics 2024-07-25 Martin Millon , Kevin Michalewicz , Frédéric Dux , Frédéric Courbin , Philip J. Marshall

Here we apply hyperspectral bright field imaging to collect computed tomographic images with excellent energy resolution (800 eV), applying it for the first time to map the distribution of stain in a fixed biological sample through its…

Precession of a converged beam during acquisition of a 4D-STEM dataset improves strain, orientation, and phase mapping accuracy by averaging over continuous angles of illumination. Precession experiments usually rely on integrated systems,…

Instrumentation and Detectors · Physics 2025-10-20 Stephanie M. Ribet , Rohan Dhall , Colin Ophus , Karen C. Bustillo

Fluorescence microscopy and derived techniques are continuously looking for photodetectors able to guarantee increased sensitivity, high spatial and temporal resolution and ease of integration into modern microscopy architectures. Recent…

In multi-photon microscopy (MPM), a recent in-vivo fluorescence microscopy system, the task of image restoration can be decomposed into two interlinked inverse problems: firstly, the characterization of the Point Spread Function (PSF) and…

Image and Video Processing · Electrical Eng. & Systems 2024-11-08 Julien Ajdenbaum , Emilie Chouzenoux , Claire Lefort , Ségolène Martin , Jean-Christophe Pesquet

We introduce a denoising method for four-dimensional scanning transmission electron microscopy (4D-STEM) that relies on processing local, scan position-independent electron event-sparse data stacks, called event-sparse stack denoising. This…

Medical Physics · Physics 2025-12-12 Gregory Nordahl , Rebekka Klemmt , Espen Drath Bøjesen

Event cameras are novel bio-inspired vision sensors that output pixel-level intensity changes in microsecond accuracy with a high dynamic range and low power consumption. Despite these advantages, event cameras cannot be directly applied to…

Computer Vision and Pattern Recognition · Computer Science 2022-11-02 Jinjin Gu , Jinan Zhou , Ringo Sai Wo Chu , Yan Chen , Jiawei Zhang , Xuanye Cheng , Song Zhang , Jimmy S. Ren

Spatial Transcriptomics (ST) allows a high-resolution measurement of RNA sequence abundance by systematically connecting cell morphology depicted in Hematoxylin and Eosin (H&E) stained histology images to spatially resolved gene…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Sichen Zhu , Yuchen Zhu , Molei Tao , Peng Qiu

Quantifying the number of molecules from fluorescence microscopy measurements is an important topic in cell biology and medical research. In this work, we present a consecutive algorithm for super-resolution (STED) scanning microscopy that…

Applications · Statistics 2023-10-03 Katharina Proksch , Frank Werner , Jan Keller-Findeisen , Haisen Ta , Axel Munk

The spectral energy distribution (SED) of observed stars in wide-field images is crucial for chromatic point spread function (PSF) modelling methods, which use unresolved stars as integrated spectral samples of the PSF across the field of…

Instrumentation and Methods for Astrophysics · Physics 2025-02-19 Ezequiel Centofanti , Samuel Farrens , Jean-Luc Starck , Tobias Liaudat , Alex Szapiro , Jennifer Pollack

Diffuse optical imaging (DOI) offers valuable insights into scattering mediums, but the quest for high-resolution imaging often requires dense sampling strategies, leading to higher imaging errors and lengthy acquisition times. This work…

Optics · Physics 2025-04-07 Ben Wiesel , Shlomi Arnon

Advances in 3D reconstruction using neural rendering have enabled high-quality 3D capture. However, they often fail when the input imagery is corrupted by motion blur, due to fast motion of the camera or the objects in the scene. This work…

Image and Video Processing · Electrical Eng. & Systems 2025-06-30 Sai Sri Teja , Sreevidya Chintalapati , Vinayak Gupta , Mukund Varma T , Haejoon Lee , Aswin Sankaranarayanan , Kaushik Mitra

Event cameras are bio-inspired sensors that offer several advantages, such as low latency, high-speed and high dynamic range, to tackle challenging scenarios in computer vision. This paper presents a solution to the problem of 3D…

Computer Vision and Pattern Recognition · Computer Science 2019-01-21 Yi Zhou , Guillermo Gallego , Henri Rebecq , Laurent Kneip , Hongdong Li , Davide Scaramuzza

Nowadays, modern electron microscopes deliver images at atomic scale. The precise atomic structure encodes information about material properties. Thus, an important ingredient in the image analysis is to locate the centers of the atoms…

Computer Vision and Pattern Recognition · Computer Science 2017-09-13 Benjamin Berkels , Benedikt Wirth

Diffusion models have demonstrated remarkable generative capabilities in image processing tasks. We propose a Sparse condition Temporal Rewighted Integrated Distribution Estimation guided diffusion model (STRIDE) for sparse-view CT…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Zekun Zhou , Yanru Gong , Liu Shi , Qiegen Liu

We introduce Seed-to-Seed Translation (StS), a novel approach for Image-to-Image Translation using diffusion models (DMs), aimed at translations that require close adherence to the structure of the source image. In contrast to existing…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Or Greenberg , Eran Kishon , Dani Lischinski

Tokenizers are a key component of state-of-the-art generative image models, extracting the most important features from the signal while reducing data dimension and redundancy. Most current tokenizers are based on KL-regularized variational…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Théophane Vallaeys , Jakob Verbeek , Matthieu Cord

In this work, we propose a structured illumination (SI) method based on a two-photon excitation (TPE) scanning laser beam. Advantages of TPE methods include optical sectioning, low photo-toxicity, and robustness in the face of sample…

Biological Physics · Physics 2016-09-16 Alex Bardales , Qinggele Li , Bingzhao Zhu , Xiaodong Tao , Marc Reinig , Joel Kubby