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To address the computational challenges of ab initio molecular dynamics and the accuracy limitations of empirical force fields, the introduction of machine learning force fields has proven effective in various systems including metals and…

Soft Condensed Matter · Physics 2023-12-18 Junbao Hu , Liyang Zhou , Jian Jiang

Isothermal-isobaric molecular dynamics simulations are used to examine the microscopic structure and some properties of water-methanol liquid mixture. The TIP4P/2005 and SPC/E water models are combined with the united atom TraPPE and the…

Soft Condensed Matter · Physics 2019-03-28 M. Cruz Sanchez , H. Dominguez , O. Pizio

In this paper, we propose a novel, thermodynamically consistent phase field model to simulate the deformation and breakup of a ferrodroplet that is immersed in a viscous medium and subject to an applied uniform magnetic field. Instead of…

Fluid Dynamics · Physics 2017-10-31 Feng Bai , Rui Li , Xiaofeng Yang , Xiaoming He , Cheng Wang

Simplified, classical models of water are an integral part of atomistic molecular simulations, especially in biology and chemistry where hydration effects are critical. Yet, despite several decades of effort, these models are still far from…

Chemical Physics · Physics 2015-01-13 Saeed Izadi , Ramu Anandakrishnan , Alexey V. Onufriev

Aerodynamic loads play a central role in many fluid dynamics applications, and we present a method for identifying the structures (or modes) in a flow that make dominant contributions to the time-varying aerodynamic loads in a flow. The…

Fluid Dynamics · Physics 2025-03-05 Suryansh Prakhar , Jung-Hee Seo , Rajat Mittal

New experiments for water at the surface of proteins at very low temperature display intriguing dynamic behaviors. The extreme conditions of these experiments make it difficult to explore the wide range of thermodynamic state points needed…

Force-matched water models provide a practical route from first-principles reference data to long classical and path-integral molecular simulations. Previous flexible four-site potentials in the spirit of q-TIP4P/F showed that fitting…

Chemical Physics · Physics 2026-05-26 Jan Kessler , Thomas Spura , Kristof Karhan , Thomas D. Kühne

Accurate, yet computationally efficient energy functions are essential for state-of-the art molecular dynamics (MD) studies of condensed phase systems. Here, a generic workflow based on a combination of machine learning-based and empirical…

Chemical Physics · Physics 2025-07-01 Eric D. Boittier , Silvan Käser , Markus Meuwly

Traditional force fields commonly use a combination of bonded torsional terms and empirically scaled non-bonded interactions to capture 1-4 energies and forces of atoms separated by three bonds in a molecule. While this approach can yield…

An adaptive modeling method (AMM) that couples a deep neural network potential and a classical force field is introduced to address the accuracy-efficiency dilemma faced by the molecular simulation community. The AMM simulated system is…

Chemical Physics · Physics 2018-11-14 Linfeng Zhang , Han Wang , Weinan E

The Many-Body Expansion (MBE) is a useful tool to simulate condensed phase chemical systems, often avoiding the steep computational cost of usual electronic structure methods. However, it often requires higher than 2-body terms to achieve…

Chemical Physics · Physics 2019-11-21 Srimukh Prasad Veccham , Joonho Lee , Martin Head-Gordon

A new molecular dynamics model in which the point charges on atomic sites are allowed to fluctuate in response to the environment is developed and applied to water. The idea for treating charges as variables is based on the concept of…

chem-ph · Physics 2009-10-22 Steven W. Rick , Steven J. Stuart , B. J. Berne

Dynamic structuring of water is a key player in a large class of processes underlying biochemical and technological developments today, the latter often involving electric fields. However, the anisotropic coupling between the water…

Soft Condensed Matter · Physics 2019-05-29 Andreas Baer , Zoran Miličević , David M. Smith , Ana-Sunčana Smith

To understand the performance of popular density-functional theory (DFT) exchange-correlation (xc) functionals in simulations of liquid water, water monomers and dimers were extracted from a PBE simulation of liquid water and examined with…

Materials Science · Physics 2009-10-21 Biswajit Santra , Angelos Michaelides , Matthias Scheffler

Mechanistic understanding and rational design of complex chemical systems depend on fast and accurate predictions of electronic structures beyond individual building blocks. However, if the system exceeds hundreds of atoms, first-principles…

Chemical Physics · Physics 2026-04-13 Siqi Chen , Zhiqiang Wang , Yili Shen , Xianqi Deng , Xi Cheng , Cheng-Wei Ju , Jun Yi , Guo Ling , Dieaa Alhmoud , Hui Guan , Zhou Lin

We show how machine learning techniques based on Bayesian inference can be used to reach new levels of realism in the computer simulation of molecular materials, focusing here on water. We train our machine-learning algorithm using…

Materials Science · Physics 2013-02-25 Albert P. Bartok , Michael J. Gillan , Frederick R. Manby , Gabor Csanyi

Spherical truncations of Coulomb interactions in standard models for water permit efficient molecular simulations and can give remarkably accurate results for the structure of the uniform liquid. However truncations are known to produce…

Statistical Mechanics · Physics 2009-11-13 Jocelyn M. Rodgers , John D. Weeks

Electrochemical interfaces are of fundamental importance in electrocatalysis, batteries, and metal corrosion. Finite-field methods are one of most reliable approaches for modeling electrochemical interfaces in complete cells under realistic…

Chemical Physics · Physics 2025-06-13 Chaoqiang Feng , Bin Jiang

In this work we present the dielectric behavior of water with a novel flexible model that improved all three sites water models Different concentrations of the ionic liquid 1- butyl-3-methylimidazolium [bmim]…

Machine learning force fields show great promise in enabling more accurate molecular dynamics simulations compared to manually derived ones. Much of the progress in recent years was driven by exploiting prior knowledge about physical…

Machine Learning · Computer Science 2025-09-11 Andreas Burger , Luca Thiede , Alán Aspuru-Guzik , Nandita Vijaykumar