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Functional connectivity is a fundamental property of neural networks that quantifies the segregation and integration of information between cortical areas. Due to mathematical complexity, a theory that could explain how the parameters of…

Neurons and Cognition · Quantitative Biology 2016-05-27 Diego Fasoli , Anna Cattani , Stefano Panzeri

Starting from the morphological-functional assumption of the fractal brain, a mathematical model is given by activating brain non-differentiable dynamics through the determinism-nondeterminism inference of the responsible mechanisms. The…

Neurons and Cognition · Quantitative Biology 2015-11-18 Maricel Agop , Alina Gavrilut , Gabriel Crumpei , Mitica Craus , Vlad Birlescu

The human brain exhibits a relatively stable spatiotemporal organization that supports brain function and can be manipulated via local brain stimulation. Such perturbations to local cortical dynamics are globally integrated by distinct…

Neurons and Cognition · Quantitative Biology 2018-01-19 Leonardo L. Gollo , James A. Roberts , Luca Cocchi

Dynamical wiring and rewiring in neural networks are carried out by activity-dependent growth and retraction of axons and dendrites, guided by gudance molecules, released by target cells. Experience-dependent structural changes in cortical…

Neurons and Cognition · Quantitative Biology 2007-05-23 Fail M. Gafarov

Large bundles of myelinated axons, called white matter, anatomically connect disparate brain regions together and compose the structural core of the human connectome. We recently proposed a method of measuring the local integrity along the…

Applications · Statistics 2018-09-18 Yo Joong Choe , Sivaraman Balakrishnan , Aarti Singh , Jean M. Vettel , Timothy Verstynen

Structural connectivity in the brain is typically studied by reducing its observation to a single spatial resolution. However, the brain possesses a rich architecture organized over multiple scales linked to one another. We explored the…

Physics and Society · Physics 2020-09-07 Muhua Zheng , Antoine Allard , Patric Hagmann , Yasser Alemán-Gómez , M. Ángeles Serrano

The concept of optimal communication channels shapes our understanding of wave-based communication. Its analysis, however, always pertains to specific communication-domain geometries, without a general theory of scaling laws or fundamental…

Information Theory · Computer Science 2022-05-12 Zeyu Kuang , David A. B. Miller , Owen D. Miller

Understanding the relation between cortical neuronal network structure and neuronal activity is a fundamental unresolved question in neuroscience, with implications to our understanding of the mechanism by which neuronal networks evolve…

Computational models of cortical activity provide insight into the mechanisms of higher-order processing in the human brain including planning, perception and the control of movement. Activity in the cortex is ongoing even in the absence of…

Neurons and Cognition · Quantitative Biology 2023-07-07 Lysea Haggie , Thor Besier , Angus McMorland

We apply an information theoretic treatment of action potential time series measured with microelectrode arrays to estimate the connectivity of mammalian neuronal cell assemblies grown {\it in vitro}. We infer connectivity between two…

Neurons and Cognition · Quantitative Biology 2007-05-23 Luis M. A. Bettencourt , Greg J. Stephens , Michael I. Ham , Guenter W. Gross

Cognition refers to the function of information perception and processing, which is the fundamental psychological essence of human beings. It is responsible for reasoning and decision-making, while its evaluation is significant for the…

Human-Computer Interaction · Computer Science 2024-08-28 Jun Chen , Anqi Chen , Bingkun Jiang , Mohammad S. Obaidat , Ni Li , Xinyu Zhang

In this work we challenge the main conclusions of Gu et al work (Controllability of structural brain networks. Nature communications 6, 8414, doi:10.1038/ncomms9414, 2015) on brain controllability. Using the same methods and analyses on…

Neurons and Cognition · Quantitative Biology 2018-07-10 Chengyi Tu , Rodrigo P. Rocha , Maurizio Corbetta , Sandro Zampieri , Marzo Zorzi , Samir Suweis

Already two decades passed since the first applications of graph theory to brain neuroimaging. Since that early description, the characterization of the brain as a very large interacting complex network has evolved in several directions. In…

Neurons and Cognition · Quantitative Biology 2021-12-21 Dante R. Chialvo , Ignacio Cifre , Jeremi K. Ochab

Recent studies have demonstrated the existence of community structure and rich club nodes, (i.e., highly interconnected, high degree hub nodes), in human brain functional networks. The cognitive relevance of the detected modules and hubs…

Social and Information Networks · Computer Science 2014-07-08 S. Sarkar , S. Chawla , H. Weng

The human connectome at the level of fiber tracts between brain regions has been shown to differ in patients with brain disorders compared to healthy control groups. Nonetheless, there is a potentially large number of different network…

Neurons and Cognition · Quantitative Biology 2013-10-16 Marcus Kaiser

Large-scale white matter pathways crisscrossing the cortex create a complex pattern of connectivity that underlies human cognitive function. Generative mechanisms for this architecture have been difficult to identify in part because little…

Neurons and Cognition · Quantitative Biology 2015-06-16 Florian Klimm , Danielle S. Bassett , Jean M. Carlson , Peter J. Mucha

Brain activity is intrinsically a neural dynamic process constrained by anatomical space. This leads to significant variations in spatial distribution patterns and correlation patterns of neural activity across variable and heterogeneous…

Machine Learning · Computer Science 2026-03-10 Hongjie Jiang , Yifei Tang , Shuqiang Wang

The behavior of many complex systems is determined by a core of densely interconnected units. While many methods are available to identify the core of a network when connections between nodes are all of the same type, a principled approach…

Neurons and Cognition · Quantitative Biology 2018-09-14 Federico Battiston , Jeremy Guillon , Mario Chavez , Vito Latora , Fabrizio De Vico Fallani

Brain metabolism is controlled by complex regulation mechanisms. As part of their nature many complex systems show scaling behavior in their timeseries data. Corresponding scaling exponents can sometimes be used to characterize these…

Condensed Matter · Physics 2007-05-23 Stefan Thurner , Christian Windischberger , Ewald Moser , Markus Barth

The network architecture of the human brain has become a feature of increasing interest to the neuroscientific community, largely because of its potential to illuminate human cognition, its variation over development and aging, and its…

Neurons and Cognition · Quantitative Biology 2016-11-07 Richard F. Betzel , Danielle S. Bassett