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Water diffusion through membrane proteins is a key aspect of cellular function. Essential processes of cellular metabolism are driven by osmotic pressure, which depends on water channels. Membrane proteins such as aquaporins (AQPs) are…

Soft Condensed Matter · Physics 2021-11-03 Miguel A. Gonzalez , Alberto Zaragoza , Charlotte I. Lynch , Mark S. P. Sansom , Chantal Valeriani

The study of liquid-liquid phase transition has attracted considerable attention. One interesting example of such phenomenon is phosphorus for which the existence a first-order phase transition between a low density insulating molecular…

Soft Condensed Matter · Physics 2021-08-25 Manyi Yang , Tarak Karmakar , Michele Parrinello

A novel liquid-liquid phase transition has been proposed and investigated in a wide variety of pure substances recently, including water, silica and silicon. From computer simulations using the Stillinger-Weber classical empirical…

Statistical Mechanics · Physics 2015-05-27 Vishwas V Vasisht , Shibu Saw , Srikanth Sastry

For a deeply supercooled liquid just above its glass transition temperature, we present a simple thermodynamic model, where the deeply supercooled liquid is assumed to be a mixture of solid-like and liquid-like micro regions. The mole…

Statistical Mechanics · Physics 2012-10-17 Hiroshi Matsuoka

Specialized Monte Carlo simulations and the moment free energy (MFE) method are employed to study liquid-gas phase equilibria in size-disperse fluids. The investigation is made subject to the constraint of fixed polydispersity, i.e. the…

Soft Condensed Matter · Physics 2009-11-10 Nigel B. Wilding , Moreno Fasolo , Peter Sollich

We find that a system of particles interacting through a simple isotropic potential with a softened core is able to exhibit a rich phase behavior including: a liquid-liquid phase transition in the supercooled phase, as has been suggested…

Soft Condensed Matter · Physics 2009-10-31 G. Malescio , G. Pellicane

The existence of a 'crossover region' in glass-forming liquids has long been considered as a general phenomenon that is as important as the glass transition. One potential origin for the crossover behavior is a liquid-to-liquid phase…

Materials Science · Physics 2015-09-14 S. Lan , M. Blodgett , K. F. Kelton , X. -L. Wang

Simulating liquid water to an accuracy that matches its wealth of available experimental data requires both precise electronic structure methods and reliable sampling of nuclear (quantum) motion. This is challenging because applying the…

Simplified, classical models of water are an integral part of atomistic molecular simulations, especially in biology and chemistry where hydration effects are critical. Yet, despite several decades of effort, these models are still far from…

Chemical Physics · Physics 2015-01-13 Saeed Izadi , Ramu Anandakrishnan , Alexey V. Onufriev

We study the behavior of ambient temperature water under the combined effects of nanoscale confinement and applied electric field. Using molecular simulations we analyze the thermodynamic causes of field-induced expansion at some, and…

Soft Condensed Matter · Physics 2019-03-27 Dusan Bratko , Christopher D. Daub , Alenka Luzar

Poly(N-isopropylacrylamide) (PNIPAM) is a synthetic polymer that is widely studied for its thermoresponsive character. However, recent works also reported evidence of a low temperature (protein-like) dynamical transition around 225 K in…

We use molecular dynamics simulations in two dimensions to investigate the possibility that a core-softened potential can reproduce static and dynamic anomalies found experimentally in liquid water: (i) the increase in specific volume upon…

Soft Condensed Matter · Physics 2009-10-31 A. Scala , M. Reza Sadr-Lahijany , N. Giovambattista , S. V. Buldyrev , H. E. Stanley

Complex fluids such as water exhibits many anomalous phenomena, and research suggests these properties are closely tied to critical fluctuations near the liquid-liquid phase transition critical point (LLCP). However, whether a similar LLCP…

Soft Condensed Matter · Physics 2026-05-06 Lin Ma , Xiaodong Yang , Xinjia Zhou , Gang Sun , Zhen Wei Wu

Previous studies have suggested a conundrum in the relaxation dynamics of polydisperse supercooled liquids. It has been shown that in two dimensions, the relative relaxation times of particles of different sizes become more similar as the…

Soft Condensed Matter · Physics 2025-03-06 Ilian Pihlajamaa , Lotte van Gessel , Corentin Laudicina , Luc van Burik , Liesbeth Janssen

We report a Monte Carlo simulation study of the properties of highly asymmetric binary hard sphere mixtures. This system is treated within an effective fluid approximation in which the large particles interact through a depletion potential…

Statistical Mechanics · Physics 2009-11-11 Julio Largo , Nigel B. Wilding

In this work, a two dimensional system of polymer grafted nanoparticles is analyzed using large-scale Langevin Dymanics simulations. Effective core-softened potentials were obtained for two cases: one where the polymers are free to rotate…

Soft Condensed Matter · Physics 2021-06-25 Murilo S. Marques , Thiago P. Nogueira , Marcia C. Barbosa , José Rafael Bordin

The liquid-liquid phase transition in high-pressure Hydrogen is a problem of longstanding and controversy. The recent Nature paper by Cheng et al. [vol. 585, p. 217] makes a set of strong claims to the effect that all the previous density…

Other Condensed Matter · Physics 2020-12-29 Valentin V. Karasiev , Joshua Hinz , S. X. Hu , S. B. Trickey

For a wide range of modern soft functional materials the selective transport of sub-nanometer-sized molecules (`penetrants') through a stimuli-responsive polymeric membrane is key to the desired function. In this study, we investigate the…

Soft Condensed Matter · Physics 2018-08-28 Matej Kanduc , Won Kyu Kim , Rafael Roa , Joachim Dzubiella

The stability-limit conjecture (SLC) proposes that the liquid spinodal of water returns to positive pressure in the supercooled region, and that the apparent divergence of water's thermodynamic response functions as temperature decreases…

Statistical Mechanics · Physics 2019-07-24 Pheerawich Chitnelawong , Francesco Sciortino , Peter H. Poole

Recently it was shown that the WAC model for liquid silica [L. V. Woodcock, C. A. Angell, and P. Cheeseman, J. Chem. Phys. 65, 1565 (1976)] is remarkably close to having a liquid-liquid critical point (LLCP). We demonstrate that increasing…

Soft Condensed Matter · Physics 2016-03-30 Erik Lascaris