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This document is an abbreviated version of the law review, led by Alexander Q. Gilbert, entitled: "Major Federal Actions Significantly Affecting the Quality of the Space Environment: Applying NEPA to Federal and Federally Authorized Outer…

Extended Reality (XR) technologies are increasingly tested outside the lab, in homes, schools, and public spaces. While this shift enables more realistic user insights, it also introduces safety challenges that are often overlooked.…

The rapid cost growth of flagship space missions has created a crisis for astronomy and planetary science. We have hit the funding wall. For the past 3 decades scientists have not had to think much about how space technology would change…

In this work, we virtually study the intra-arterial targeted drug delivery. Specifically, this work models and quantifies the uncertainties associated with catheter steerability limitations. We classify catheter's limited steerability into…

As miniaturized spacecraft (e.g., cubesats and smallsats) and instrumentation become an increasingly indispensable part of space exploration and scientific investigations, it is important to understand their potential susceptibility to…

In contrast to manned missions, the application of autonomous robots for space exploration missions decreases the safety concerns of the exploration missions while extending the exploration distance since returning transportation is not…

Thanks to post-flight analyses of several artificial satellites carried out during last years, the meteoroids hazard for space navigation and in-orbit satellites permanence is now clear. Even if catastrophic impact is a rare event, high…

Safety is one of the key issues preventing the deployment of reinforcement learning techniques in real-world robots. While most approaches in the Safe Reinforcement Learning area do not require prior knowledge of constraints and robot…

Galactic cosmic rays and solar energetic particles (SEPs) affect the performance of instruments carried on board space missions and are the source of the absorbed dose to astronauts. Particles above 100 MeV are the most penetrating. The…

In recent decades, traditional drug research and development have been facing challenges such as high cost, long timelines, and high risks. To address these issues, many computational approaches have been suggested for predicting the…

Beam-beam interactions and space-charge effects belong to the category of the most long-standing issues in beam physics, and even today, after several decades of very active exploration and development of counter-measures, they still pose…

Spacecraft potential has often been used to infer electron density with much higher time resolution than is typically possible with plasma instruments. However, recently two studies by Torkar et al. 2017 and Graham et al. 2018 have shown…

The possibility that the magnetic field is strongly correlated with the large-scale structure of the universe has been recently considered in the literature. In this scenario the intergalactic magnetic field has a strong ($\mu$G) regular…

As wearable health technologies have grown more sophisticated, the distinction between "wellness" and "medical" devices has become increasingly blurred. While some features undergo formal U.S. Food and Drug Administration (FDA) review, many…

Radiopharmaceutical therapies are expanding rapidly, but clinical evidence generation is limited by operational constraints and biological heterogeneity in radiopharmaceutical delivery and radiation risk. Virtual theranostic trials can run…

To study stellar populations, it is common to combine chemical abundances from different spectroscopic surveys/studies where different setups were used. These inhomogeneities can lead us to inaccurate scientific conclusions. In this work,…

Is the complexity of medical product (medicines and medical devices) regulation impacting innovation in the US? If so, how? Here, this question is investigated as follows: Various novel proxy metrics of regulation (FDA-issued guidelines)…

This paper addresses: Evolution of the space systems environment, including space system proliferation and space systems as critical infrastructure Cyber threats to, and vulnerabilities of, space systems Alternative approaches to meeting…

Mars is the next frontier for the space explorers to demonstrate the extent of human presence in space beyond low-earth orbit. Both government and private space industries have been fascinated by Mars quest to attempt a crewed expedition to…

We derive general constraints on the relic abundances of a long-lived particle which mainly decays into a neutrino (and something else) at cosmological time scales. Such an exotic particle may show up in various particle-physics models…