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Medical imaging systems are commonly assessed and optimized by use of objective measures of image quality (IQ). The Ideal Observer (IO) performance has been advocated to provide a figure-of-merit for use in assessing and optimizing imaging…

Signal Processing · Electrical Eng. & Systems 2020-07-16 Weimin Zhou , Hua Li , Mark A. Anastasio

The ideal observer (IO) sets an upper performance limit among all observers and has been advocated for assessing and optimizing imaging systems. For general joint detection and estimation (detection-estimation) tasks, estimation ROC (EROC)…

Signal Processing · Electrical Eng. & Systems 2021-12-03 Kaiyan Li , Weimin Zhou , Hua Li , Mark A. Anastasio

Medical imaging systems are commonly assessed and optimized by the use of objective measures of image quality (IQ). The performance of the ideal observer (IO) acting on imaging measurements has long been advocated as a figure-of-merit to…

Medical Physics · Physics 2025-01-17 Kaiyan Li , Prabhat Kc , Hua Li , Kyle J. Myers , Mark A. Anastasio , Rongping Zeng

The objective assessment of image quality (IQ) has been advocated for the analysis and optimization of medical imaging systems. One method of obtaining such IQ metrics is through a mathematical observer. The Bayesian ideal observer is…

Signal Processing · Electrical Eng. & Systems 2025-08-19 Jason L. Granstedt , Weimin Zhou , Mark A. Anastasio

The Ideal Observer (IO) performance has been advocated when optimizing medical imaging systems for signal detection tasks. However, analytical computation of the IO test statistic is generally intractable. To approximate the IO test…

Signal Processing · Electrical Eng. & Systems 2020-01-28 Weimin Zhou , Mark A. Anastasio

Medical imaging systems are often evaluated and optimized via objective, or task-specific, measures of image quality (IQ) that quantify the performance of an observer on a specific clinically-relevant task. The performance of the Bayesian…

Signal Processing · Electrical Eng. & Systems 2023-04-04 Weimin Zhou , Umberto Villa , Mark A. Anastasio

It is widely accepted that the Bayesian ideal observer (IO) should be used to guide the objective assessment and optimization of medical imaging systems. The IO employs complete task-specific information to compute test statistics for…

Signal Processing · Electrical Eng. & Systems 2025-02-03 Weimin Zhou

Task-based assessment of image quality (IQ) is critically important for the design and optimization of medical imaging systems. Ideal observers, including the Bayesian Ideal Observer (IO) and the ideal linear observer, i.e., the Hotelling…

Image and Video Processing · Electrical Eng. & Systems 2026-05-29 Weimin Zhou

In medical imaging, it is widely recognized that image quality should be objectively evaluated based on performance in clinical tasks. To evaluate performance in signal-detection tasks, the ideal observer (IO) is optimal but also…

Medical Physics · Physics 2022-03-09 Md Ashequr Rahman , Zitong Yu , Abhinav K. Jha

Objective, task-based measures of image quality (IQ) have been widely advocated for assessing and optimizing medical imaging technologies. Besides signal detection theory-based measures, information-theoretic quantities have been proposed…

Image and Video Processing · Electrical Eng. & Systems 2026-03-25 Changjie Lu , Sourya Sengupta , Hua Li , Mark A. Anastasio

A variety of deep neural network (DNN)-based image denoising methods have been proposed for use with medical images. Traditional measures of image quality (IQ) have been employed to optimize and evaluate these methods. However, the…

Image and Video Processing · Electrical Eng. & Systems 2021-04-30 Kaiyan Li , Weimin Zhou , Hua Li , Mark A. Anastasio

It is widely accepted that optimization of imaging system performance should be guided by task-based measures of image quality (IQ). It has been advocated that imaging hardware or data-acquisition designs should be optimized by use of an…

Computer Vision and Pattern Recognition · Computer Science 2019-05-16 Yujia Chen , Yang Lou , Kun Wang , Matthew A. Kupinski , Mark A. Anastasio

Deep learning-based image super-resolution (DL-SR) has shown great promise in medical imaging applications. To date, most of the proposed methods for DL-SR have only been assessed by use of traditional measures of image quality (IQ) that…

Image and Video Processing · Electrical Eng. & Systems 2021-07-07 Xiaohui Zhang , Varun A. Kelkar , Jason Granstedt , Hua Li , Mark A. Anastasio

The smooth operation of largely deployed Internet of Things (IoT) applications will depend on, among other things, effective infrastructure failure detection. Access failures in wireless network Base Stations (BSs) produce a phenomenon…

Signal Processing · Electrical Eng. & Systems 2020-02-05 Orestes Manzanilla-Salazar , Filippo Malandra , Hakim Mellah , Constant Wette , Brunilde Sanso

We develop a new statistical ideal observer model that performs holistic visual search (or gist) processing in part by placing thresholds on minimum extractable image features. In this model, the ideal observer reduces the number of free…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Howard C. Gifford

The goal of this thesis is to provide a framework for the use of task-based metrics of image quality to aid in the design, implementation, and evaluation of CT image reconstruction algorithms and CT systems in general. We support the view…

Medical Physics · Physics 2015-05-18 Adrian A. Sanchez

Inverse optimization (IO) aims to determine optimization model parameters from observed decisions. However, IO is not part of a data scientist's toolkit in practice, especially as many general-purpose machine learning packages are widely…

Optimization and Control · Mathematics 2021-02-23 Elaheh H. Iraj , Daria Terekhov

Spectral imaging is a method in medical x-ray imaging to extract information about the object constituents by the material-specific energy dependence of x-ray attenuation. Contrast-enhanced spectral imaging has been thoroughly investigated,…

Medical Physics · Physics 2021-01-26 Erik Fredenberg , Magnus Aslund , Bjorn Cederstrom , Mats Lundqvist , Mats Danielsson

Bayesian Optimization (BO) is a common solution to search optimal hyperparameters based on sample observations of a machine learning model. Existing BO algorithms could converge slowly even collapse when the potential observation noise…

Computer Vision and Pattern Recognition · Computer Science 2022-10-10 Lei Cui , Yangguang Li , Xin Lu , Dong An , Fenggang Liu

The optimal receiver operating characteristic (ROC) curve, giving the maximum probability of detection as a function of the probability of false alarm, is a key information-theoretic indicator of the difficulty of a binary hypothesis…

Information Theory · Computer Science 2025-06-10 Bruce Hajek , Xiaohan Kang
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